Metabolic bone disease

Question 1

what are metabolic bone diseases

Answer 1

these are conditions that result from deficiency, failure, defects in metabolism, deposition of minerals, hormones, deposition of osteocytes

Question 2

risk factors of metab bone disease

Answer 2

1) smoking
2) alcohol
3) excess intake of steroids

Question 3

osteoplastic activity

Answer 3

consistent layering of osteoid matters for bone development

Question 4

osteoclastic activity

Answer 4

a form of bone destruction

Question 5

_ is a major amino acid for collagen formation

Answer 5

hydroxyproline

Question 6

causes of bone metab dx

Answer 6

1) liver failure
2) kidney disease (stage 5)
3) GIT dx eg Chron’s disease
4) low Ca, low PTH, low Mg, low Vit B12

Question 7

classification of metab bone disease

Answer 7

1) formation of normal mineralization, but there is defect in accumulation. Occurs in osteoporosis
2) formation of abnormal mineralization especially in conditions like osteomalacia where there is Vit D deficiency
3) formation of abnormal mineralization in conditions of CKD where renal osteodystrophy is a major example
4) formation of abnormal mineralization due to hypo function of PTH gland