Urethritis and Cervicitis MR Flashcards
1
Q
Causes of vaginal discharge (5)
A
- physiological
- cervicitis
- genital candidiasis
- bacterial vaginosis
- other ie vaginitis and foreign body (tampon)
2
Q
Chlamydia
A
- intracellular bacteria
2. biphasic lifecycle about 24-48 hours
3
Q
Life cycle
A
- attachment and entry of elementary body into cell (6 hrs)
- Formation of reticulate body (8 hrs)
- Binary fission of reticulate body (24 hrs)
- reorganization of reticulate bodies into elementary bodies (30 hrs)
- release of elementary bodies (48 hrs)
4
Q
Types of diagnosis
A
- NAAT (nucleic acid amplification testing)
2. CT diagnosis
5
Q
Specimen collection
A
Males: FVU
Females:
1. vulvovaginal swab for NAAT
2. speculum examination
6
Q
Treatment
A
- Azithromycin 1gm stat
- Doxycycline 100mg bid 7 days
(pregnant woman)
- Azithromycin 1g stat
- Amoxycillin 500mg tid for 7 days
7
Q
Neisseria gonorrhoea
A
- gram negative diplococcus
- humans are the only natural host
- infect non-cornified epithelium via intracellular replication
- oxidase positive
- fastidious growth
- chromosomal or plasmid mediated antibiotic resistance
8
Q
Pathogenic and defence mechanisms (5)
A
- Pilin for adherence and resistance to neutrophils
- Opa proteins for adherence
- lipooligosaccharide (LOS)
- Serum resistance
- IgA protease
9
Q
Gonorrhea treatment
A
(uncomplicated)
If sensitivities unknown,
1. ceftriaxone 500mg IMI stat
2. Azithromycin 1g po stat
If sensitives known,
- Ciprofloxacin
- Azithromycin
10
Q
PID treatment
A
- ceftriaxone 500mg IMI stat
2. doxycycline 100mg bid 14 day +/- metronidazole 400mg bid 14 day