Urethritis and Cervicitis MR Flashcards

1
Q

Causes of vaginal discharge (5)

A
  1. physiological
  2. cervicitis
  3. genital candidiasis
  4. bacterial vaginosis
  5. other ie vaginitis and foreign body (tampon)
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2
Q

Chlamydia

A
  1. intracellular bacteria

2. biphasic lifecycle about 24-48 hours

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3
Q

Life cycle

A
  1. attachment and entry of elementary body into cell (6 hrs)
  2. Formation of reticulate body (8 hrs)
  3. Binary fission of reticulate body (24 hrs)
  4. reorganization of reticulate bodies into elementary bodies (30 hrs)
  5. release of elementary bodies (48 hrs)
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4
Q

Types of diagnosis

A
  1. NAAT (nucleic acid amplification testing)

2. CT diagnosis

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5
Q

Specimen collection

A

Males: FVU
Females:
1. vulvovaginal swab for NAAT
2. speculum examination

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6
Q

Treatment

A
  1. Azithromycin 1gm stat
  2. Doxycycline 100mg bid 7 days

(pregnant woman)

  1. Azithromycin 1g stat
  2. Amoxycillin 500mg tid for 7 days
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7
Q

Neisseria gonorrhoea

A
  1. gram negative diplococcus
  2. humans are the only natural host
  3. infect non-cornified epithelium via intracellular replication
  4. oxidase positive
  5. fastidious growth
  6. chromosomal or plasmid mediated antibiotic resistance
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8
Q

Pathogenic and defence mechanisms (5)

A
  1. Pilin for adherence and resistance to neutrophils
  2. Opa proteins for adherence
  3. lipooligosaccharide (LOS)
  4. Serum resistance
  5. IgA protease
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9
Q

Gonorrhea treatment

A

(uncomplicated)
If sensitivities unknown,
1. ceftriaxone 500mg IMI stat
2. Azithromycin 1g po stat

If sensitives known,

  1. Ciprofloxacin
  2. Azithromycin
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10
Q

PID treatment

A
  1. ceftriaxone 500mg IMI stat

2. doxycycline 100mg bid 14 day +/- metronidazole 400mg bid 14 day

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