Urea Cycle Enzymes Flashcards

1
Q

PLP

A

Pyridoxal phosphate
Prosthetic group of all aminotransferases
Coenzyme form of pyridoxine (vitamin B6)
Metabolism of molecules with amino groups

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2
Q

Aminotransferase

A

L amino acid—>alpha keto acid
alpha-ketoglutarate–>glutamate
PLP is cofactor

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3
Q

Glutamate dehydrogenase

A

glutamate–>alpha-ketoglutarate

NADP is cofactor

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4
Q

glutaminase

A

Transport toxic ammonia out

glutamine–>glutamate

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5
Q

Alanine aminotransferase

A

alanine–>pyruvate in the liver
alpha-ketoglutarate–>glutamate
pyruvate–>alanine in the muscles
glutamate–>AKG

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