Urea Cycle Enzymes Flashcards
1
Q
PLP
A
Pyridoxal phosphate
Prosthetic group of all aminotransferases
Coenzyme form of pyridoxine (vitamin B6)
Metabolism of molecules with amino groups
2
Q
Aminotransferase
A
L amino acid—>alpha keto acid
alpha-ketoglutarate–>glutamate
PLP is cofactor
3
Q
Glutamate dehydrogenase
A
glutamate–>alpha-ketoglutarate
NADP is cofactor
4
Q
glutaminase
A
Transport toxic ammonia out
glutamine–>glutamate
5
Q
Alanine aminotransferase
A
alanine–>pyruvate in the liver
alpha-ketoglutarate–>glutamate
pyruvate–>alanine in the muscles
glutamate–>AKG