Pentose Phosphate Pathway

Question 1

Pentose Phosphate Pathway

Answer 1

Glucose 6 phosphate–>ribose-5 phosphate
Produce pentose phosphates for nucleic acid synthesis in rapidly dividing cells
Other cells (fatty acid/sterol/hormone synthesis–liver, gonads, etc) use it for the generation of electron donor NADPH for reductive biosynthesis
Erythrocytes and eyes use NADPH for fixing oxidative damage to eyes

Question 2

NADPH

Answer 2

Electron donor produced in PPP
Utilized by liver/gonads/etc for reductive biosyntehsis
Used by eyes and erythrocytes to undo oxidative damage

Question 3

Step 1

Answer 3

glucose 6-phosphate–> 6-phosphogluconate
Use G6P dehydrogenase
Inhibited by NADPH and fatty acid acetyl co-a
Yield NADPH

Question 4

Step 2

Answer 4

6 phospho-glucano-d-lactone–>6 phosphogluconate

enzyme: lactonase

Question 5

Step 3

Answer 5

6 phosphogluconate–>ribulose 5 phosphate
enzyme: 6 phosphogluconate dehydrogenase
make NADPH