Urea Cycle Flashcards

1
Q

Ammonia uptake in brain

A

Gln removes ammonia and exports to liver; Gln converted to Glu in liver, freeing NH4+ which goes to urea cycle

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2
Q

Muscle/Liver Nitrogen transfer

A

In muscle, alpha KG takes up NH3 to form Glu; Glu transaminated by ALT to Ala; Ala transported to liver, which undergoes transamination by ALT to form pyruvate and Glu (Ala donates NH3)

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