Urea Cycle Flashcards
1
Q
Ammonia uptake in brain
A
Gln removes ammonia and exports to liver; Gln converted to Glu in liver, freeing NH4+ which goes to urea cycle
2
Q
Muscle/Liver Nitrogen transfer
A
In muscle, alpha KG takes up NH3 to form Glu; Glu transaminated by ALT to Ala; Ala transported to liver, which undergoes transamination by ALT to form pyruvate and Glu (Ala donates NH3)