Enzymes Flashcards
1
Q
Uncompetitive inhibitor
A
Only binds when substrate is not bound; when substrate binds, locks substrate in place and therefore, decreases amount of functional enzyme; effects vmax and km
2
Q
Competitive Inhibitor
A
No effect on vmax; increases km
3
Q
Non-competitive inhibitor
A
Decreases vmax; no effect on km
4
Q
Uncompetitive inhibitor
A
Decreases both km and vmax
5
Q
Metalloenzymes
A
Require metal cofactors; inhibited by chelating agents (i.e.: lead poisoning) Pb inhibits aminolevulinic acid DH (involved in synthesis of heme); use EDTA b/c Pb has higher affinity for EDTA
