UREA CYCLE Flashcards

1
Q

fuel is formed from ammonium ion (from oxidative deamination), carbon dioxide (from the citric acid cycle), water, and two ATP molecules

A

Carbamoyl Phosphate

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2
Q

a cyclic biochemical pathway in which urea is produced, for excretion, using ammonium ions and aspartate molecules as nitrogen sources

A

urea cycle

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2
Q

first molecule of “fuel”
entering the cycle

A

Citrulline

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3
Q

transported in the blood to the kidneys and eliminated from the body in urine

A

urea

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4
Q

second molecule of “fuel” entering the cycle

A

Aspartate

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5
Q

Three amino acids are involved as intermediates in the operation of the urea cycle

A

arginine
ornithine
citrulline

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6
Q

Citrulline–aspartate condensation enzyme

A

argininosuccinate synthase

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7
Q

an adult excretes about __ g of urea daily in urine

A

30

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8
Q

Hydrolysis of arginine produces urea and regenerates ornithine, one of the cycle’s starting materials

A

Step 4: Urea from arginine hydrolysis.

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9
Q

“fuel” for the urea cycle

A

Carbamoyl Phosphate

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10
Q

amino acid that has a carbon-containing product that can be used to produce glucose via gluconeogenesis

A

Glucogenic amino acid

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11
Q

enzyme involved in Step 4: Urea from arginine hydrolysis

A

arginase

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12
Q

Amino acids that are degraded to acetyl CoA or acetoacetyl CoA can contribute to the formation of fatty acids or ketone
bodies

A

ketogenic

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12
Q

formed via the urea cycle is excreted in urine

A

urea

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13
Q

an amino acid that has a carbon-containing degradation
product that can be used to produce ketone bodies

A

ketogenic amino acid

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14
Q

one of several molecules eliminated from the body through urine

15
Q

TRUE / FALSE:
amino acids that are degraded to acetyl CoA (or acetoacetyl CoA) are glucogenic

A

FALSE , NOT GLUCOGENIC

16
Q

degradation requires a single step for these amino acids

A

Alanine
Serine

17
Q

two amino acids are purely ketogenic

A

leucine and lysine

17
Q

Amino acids that are degraded to citric acid cycle intermediates can serve as glucose precursors

A

glucogenic

18
Q

KETO / BOTH / GLUCO:
I - ISOLEUCINE

19
Q

how many amino acids are both glucogenic and ketogenic?

20
Q

KETO / BOTH / GLUCO:
A - ALANINE

21
Q

KETO / BOTH / GLUCO:
amino acid that can be
converted into glucose through
gluconeogenesis

22
KETO / BOTH / GLUCO: G - GLYCINE
BOTH
23
KETO / BOTH / GLUCO: L,K
KETOGENIC
24
KETO / BOTH / GLUCO: C - CYSTEIN
BOTH
25
KETO / BOTH / GLUCO: L - LEUCINE
KETOGENIC
26
KETO / BOTH / GLUCO: S - SERINE
BOTH
27
KETO / BOTH / GLUCO: T and W
BOTH
28
KETO / BOTH / GLUCO: K - LYSINE
KETOGENIC
29
KETO / BOTH / GLUCO: Amino acids that are degraded to pyruvate
BOTH
30
KETO / BOTH / GLUCO: are converted into ketone bodies
GLUCOGENESIS
31
KETO / BOTH / GLUCO: pyruvate coverted to oxaloacetate (glucogenic) or acetyl CoA (ketogenic
BOTH
32
KETO / BOTH / GLUCO: V, P, M, N, Q, E, D, H, R
GLUCO
33
KETO / BOTH / GLUCO: Y, F, I, A,G,C,S,TW
BOTH
34
KETO / BOTH / GLUCO: Y - THREONINE
BOTH
35
KETO / BOTH / GLUCO: F - PHENYLALAININE
BOTH