Uptake/Distribution Flashcards
1
Q
Four factors/steps of uptake and distribution?
A
anesthesia gas machine, lungs, blood, and tissues
2
Q
MAC
A
minimum alveolar concentration required to achieve surgical anesthesia (immobility) in 50% of patients exposed to a noxious stimulus
MAC = dose
3
Q
What agent has the lowest MAC %?
A
Iso
4
Q
What agent is the fastest?
What coefficient is this determined by?
A
Des, technically, due to its lowest Blood/gas coefficient
In reality, N2O would be quicker due to drastic concentration effect
5
Q
What drug has the highest oil/gas coefficient so is the most potent?
A
Iso
6
Q
Factors that increase anesthetic effect/speed?
A
Low solubility Low CO High FGF High RR High concentration of agent Use of second gas effect
7
Q
Factors that lead to a slower induction?
A
High blood/gas solubility (wants to stay in blood) High CO Low RR Low FGF Low concentrations of agent V/Q deficits (trauma, disease, etc. )
