Dose Response Curve Flashcards
1
Q
Dose response curve allows us to determine what?
A
affinity/potency, efficacy, variability, and slope
2
Q
Efficacy
A
ability of a drug to produce a desired effect or maximum response; magnitude of response with respect to the given dose
3
Q
Affinity/Potency
A
the strength of the drug; how many mg does it take to reach desired effect?
4
Q
Variability
A
individual differences between person taking the drug
5
Q
Slope
A
looks at the margin of safety; steeper slope = smaller TI = little changes in dose will produce a big change in response/effect
6
Q
Bioavailability
A
the percentage of a drug contained in a drug product that enters the systemic circulation in an unchanged form after administration of the product
IV by definition has 100% bioavailability
