Upper motor control - Part I Flashcards
Why is yawning infectious?
mirror neurons
What is motor control?
process of initiating, directing and grading purposeful volitional movement
Muscle spindle and other sensory systems will feedback if performing motions as …
Planned or not, if you dont, readjust
Order from brain go to ________ ________ system, to fine motor control and limb movement
postural control
What is closed loop or bottom up model?
1,2,3,4
- sensory in, motor out
- ex. see ball, make decision to kick it
What is open loop or top down model?
a,b,c,d
- decision from CNS gets out as motor
- NO SENSORY
- ex. reach for water bottle without seeing it / looking up at it
What are reflexes?
sensory in, directly motion out
- ex. patellar reflex, DTRs
- withdrawal reflex when touching something hot, withdrawal hand without thinking about it
What are central patter generators?
- prewritten APPs in brain stem and spinal cord
- walking/gait pattern in written in spinal cord, can cut at medulla and still walk normally
What are the 4 levels of hierarchical motor control?
- spinal cord
- brainstem
- motor cortex
- association cortex
What is contained in level two of motor control?
brainstem
- red nucleus (rubtospinal tract)
- reticular formation
- vestibular nuclei
- tectum
- pontine nuclei
- inferior olive
What is contained in level 3 of motor control?
Motor Cortex
- Primary motor cortex
- premotor cortex
- supplementary motor area
- unimodal, Brodmann Area 6
Can lower levels of the hierarchical motor control control higher levels?
NO
- higher can control lower but not reverse
What is the LMN in the spinal cord medial to lateral orientation?
trunk to extremity
What is the LMN in the spinal cord anterior to posterior orientation?
extensors to flexors
What is the cerebral cortex (UMN in the brain) for?
extremity, skills/fine motor control
What is the brainstem (UMN in the brain) for?
trunk, gross motor control
What do level 3 and 4 of the motor control hierarchy mainly control?
extremities
most part of level 3 descend medially to _______
bilaterally, BOTH SIDES
What is within level 4 of motor control?
- Cingulate motor area in the limbic system
- posterior parietal cortex; Brodmann areas 5 and 7
- Frontal eye field: Brodmann area 8
- Language areas:
- Broca’s area 44 and 45
- Multimodal association cortex
What Brodmann area does hand-eye coordination?
5 and 7
- posterior parietal cortex
Where are the 1st, 2nd, and 3rd order neurons located in the lateral spinothalamic tract?
Which thalamic nuclei does the C-fiber mediated diffuse pain project to?
intralaminal and centromedian nuclei
What are the 3 structures in the cingulate motor area in level 4 motor control that have connected functions of reciprocal projections?
- L dorsolateral prefrontal cortex
- Orbitofrontal cortex
3, Cingulate motor area
What is the function of the Left dorsolateral prefrontal cortex?
motor planning and execution
What is the function of the orbitofrontal cortex?
collecting/summarizing motor results
What ist he function of the cingulate motor area?
- calculating the “reward” of a motion
- emotion-related behaviors: reward-seeking or aversion
seeking the most reward with the least investment decides if we continue that motion
What is the alternative motor control theory?
“investment and reward”
- most reward with least investment, basic principle for computer-brain interface
What are the functions of posterior parietal cortex?
- specialized area for hand reach/grasp: apraxia, L hemisphere
- Saccadic eye movements
What is the specialized area for hand reach/grasp also doing?
- processing object size
- orientation
- hand matching (need whole hand, two fingers, etc to pick up the object)
What do saccadic eye movements help with?
eye-hand coordination
What does V1 detect?
lines only
What does V2 detect?
shape of objects
What does V4 detect?
color
What detects the WHERE and HOW of visual pathways?
dorsal stream of visual pathways
- context and spatial representation of objects: WHERE
- Visuomotor transformations: HOW
What detects the WHAT of visual pathways?
Ventral stream
What are the functions of V1,2, and 4 and what are their pathways?
V1 only detects lines with different directions, integrated into V2, the unimodal association cortex where shapes are integrated, then projected to V4 for color. There are two pathways: ventral stream to the temporal lobe and dorsal stream to parietal lobe (posterior parietal cortex Bordmann area 5 and 7) to define where structures are in space
Where does the ventral stream project?
temporal lobe
Where does the dorsal stream project?
parietal lobe
- brodmanns 5 and 7
What brodmanns area is the unimodal association cortex?
6
What is within the unimodal association cortex?
- supplemental motor area (SMA)
- premotor cortex (PM)
> dorsal and ventral
What is the primary motor cortex?
M1 - Brodmann area 4
What are the functions of SMA in open loop top down?
Coordination of sequential tasks
- deciding to do something without external stimuli
- ex. play piano
Where is the supplementary motor area?
Medial Brodmann area 6
What are the major motor control functions for Brodmann areas 5 and 7?
Praxis
- ideational
- motor
- etc.
Hand-eye Coordination
What does a simple motion?
unilateral M1/S1
What if we do a simple motion with our left hand? What is activated?
Right M1 and S1 activated when left fingers touch or do a simple motion
What does a complex motion activate?
Unilateral M1/S1 and bilateral SMA
What if we do a complex motion with our left hand such as playing the piano, what is activated?
- Left SMA, right M1 and S1 and SMA
SMA on both sides, right M1/S1
What does iMAGERY of a complex motion activate?
bilateral SMA
Why do we get post stroke flaccidity?
- stroke compromises corticopontine tracts, which are connected to the cerebellum, which adjusts muscle tone; without control = muscles flaccid
Where is the PM?
dorsal to ventral along Brodmann area 6
What are the functions of PM in motor control?
- preparation for movement
- correct and incorrect actions
- most concentration of mirror neurons
What is context-dependent behavior ______ loop?
closed loop, bottom up
- breakfast, heavy coffee cup if full, PMA more activated, if less heavy, less activation of PMA
What kind of translator are mirror neurons?
sensory to motor
Where are mirror neurons NOT located?
occipital lobe
What is the sensorimotor pathway for somatic motor functions of mirror neurons for?
- understanding the intention of the movement: learning
What is the emotion pathway for visceral motor functions of mirror neurons?
self and social cognition
- why we cry during movies, infectious emotion but only with experience
What pathways do mirror neurons integrate?
sensorimotor pathway (Sm) and Emotion pathway (Vm)
When are you daydreaming of skiing in my boring neurobiology course, which level 3 motor control centers are active?
bilateral SMA
List out motor to sensory and sensory to motor translators in our bodies?
- motor to sensory: muscle spindle
- Sensory to motor: mirror neurons