Upper and Lower GI Disorders Flashcards
reflex of gastric contents into lower esophagus
gastroesophageal reflux disease (GERD)
What contributes to GERD sxs
- impaired esophageal motility
- defective mucosal defense
- LES dysfunction
- delayed gastric emptying
- reflux of gastric contents
- small intestine reflux of bile
Risk factors of GERD
- hiatal hernia
- incompetent LES (one of primary causes)
- decreased gastric emptying
- obesity
- pregnancy
- smoking, caffeine, and alcohol
clinical manifestations of GERD
- heartburn (most common sx)
- dyspepsia
- hyper salivation
- regurgitation
- coughing, wheezing, dyspnea
complications of GERD
- esophagitis
- Barrett’s esophagus (precancerous lesion)
diagnostic tests for GERD
- description of sxs
- reaction to GERD tx
- EGD (for complications)
collaborative care for GERD
- increased HOB 2-3 hours after eating
- high protein, low fat diet
- small frequent meals
- avoid chocolate, peppermint, caffeine, tomatoes, orange juice, and alcohol
- avoid late-night snacks or meals
- smoking cessation and weight reduction
- avoid tight clothing
- drug therapy
drugs used for GERD
- proton pump inhibits (PPI): esomeprazole (Nexium)
- H2 blockers: famotidine (Pepcid)
herniation of part of the stomach into esophagus through diaphragm
hiatal hernia
2 type of hiatal hernias
- sliding: esophagogastric junction above diaphragm when supine; most common
- paraesophageal or rolling: fundus and greater curvature of stomach pass through diaphragm on one side
which type of hiatal hernia is a medical emergency
paraesophageal or rolling hernia: section of stomach above diaphragm can become strangulated (low blood flow)
risk factors for hiatal hernia
- obesity
- pregnancy
- physical overexertion or heavy lifting
clinical manifestations of hiatal hernia
- asymptomatic or sxs similar to GERD
complications of hiatal hernia
- GERD
- ulcerations
- strangulation
diagnostic tests for hiatal hernia
EGD
collaborative care for hiatal hernia
- avoid lifting and straining (keep intraabdominal pressure low)
- similar to GERD (lift HOB, diet, avoid smoking/tight clothes)
- medication
- surgery (if medication not effective)
types of surgery for hiatal hernia
- herniorrhaphy (closure of defect)
- herniotomy (excision of the hernia sac
- Nissen fundoplication (upper part of stomach wrapped around LES to strengthen sphincter)
types of UGI bleeding
- hematemesis (bright red or coffee ground vomit)
- melena (black tarry stool)
- occult bleeding (bleeding somewhere but is undetectable to naked eye)
where is the bleeding for bright red vomit
in esophagus or acute upper GI tract
what causes melena and coffee ground vomit
blood has been digested
common causes of UGI bleeding
- esophagus (esophagitis, esophageal varices, Mallory Weiss tear)
- stomach and duodenum (PUD, gastric cancer, stress ulcers)
- drug-induced (ASA, NSAIDs, corticosteroids)
- systemic disease (liver disease, leukemia, thrombocytopenia)
assessment and management of UGI bleeding
- monitor BP and HR q 15-30 minutes
- assess signs of shock
- ABD exam
- stool guaiac, Gastroccult
- large bore IVs
- PRBCs, FFP, whole blood
- O2 per NC
- I&O
labs for UGI bleeding
- CBC (H&H)
- BUN and Cr (hypovolemia -> renal failure)
- PT/PTT/INR
- Type and cross match
diagnostic tests for UGI bleeding
EGD
collaborative care for UGI bleeding
- endoscopic hemostasis therapy
- surgical therapy
- antacids (H2 blockers; PPIs)
- avoid smoking and EtOH
- take meds w/ food
- NPO -> CL diet -> advanced as tolerated
where are ulcers located in PUD
- lower esophagus
- stomach
- duodenum (most common)
cause of PUD
gastric mucosa is damaged and unable to repair itself due to very acidic gastric acid
levels of gastric ulcers
- erosion of the mucosa
- acute ulcer into the submucosa
- chronic ulcer that gets down into the muscular and causes scarring