Care of Patients w/ Specific Cancers Flashcards

1
Q

How to identify skin cancer

A

skin self-exams monthly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

ABCDE rule for skin cancer

A
  • asymmetry
  • border irregularity
  • color changes
  • diameter >6mm
  • evolving in appearance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

risk factors for skin cancer

A
  • fair skin type (blond or red hair; blue or green eyes)
  • chronic sun exposure (leading cause)
  • indoor tanning booths
  • family Hx
  • exposure to tar or arsenic
  • living close to equator, outdoor occupations, or frequent outdoor activities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

explain skin cancer w/ darker skin

A
  • less susceptible (more melanin serves as sunscreen)

- can still get skin cancer (most often palms of hands, soles of feet, and mucous membranes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

most common form of skin cancer

A

non-melanomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

characteristics of non-menalomas

A
  • develop in epidermis and not melanocytes

- develop in sun exposed areas (face, neck, hands, arms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

precancerous lesions on skin that may go away w/ reduced sun exposure

A

actinic keratosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

most common and least deadly for of skin cancer (rare metastasize beyond skin)

A

basal cell carcinoma (BCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what do basal cell carcinomas look like

A

enlarging papule w/ pearly border, erosion, or ulcer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does actinic keratosis look like

A

flat or elevated scaly papule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

less common and highly aggressive form of skin cancer (potential for metastasis and death if not treated)

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does squamous cell carcinoma look like

A

scaly erythematous plaque, nodules, lesions, or ulcerations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what can lead to SCC around the mouth and lips

A

pipes, cigars, and cigarette smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

describe malignant melanoma

A
  • occur anywhere on skin (cutaneous melanoma) -> lesions often dark brown or black
  • can also occur in eyes, GI tract, mucous membranes, or lymph nodes
  • can metastasize to any organ
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

epidemiology of malignant melanoma

A
  • incidence and death much higher among caucasians

- genetic predisposition plus all other risk factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

most common sites for malignant melanoma

A
  • males: back and chest

- females: back and legs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

collaborative care for skin cancer

A
  • biopsy (shows type and depth)
  • treatment depends on site of tumor, stage of cancer, and patient’s age and health
  • surgical excision
  • chemo, biological, radiation therapy (if spread)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

describe laryngeal cancer

A
  • occurs in the larynx
  • most commonly squamous cell in origin
  • more common in males 55-70
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

risk factors for laryngeal cancer

A
  • prolonged use of alcohol and tobacco (most common)
  • vocal straining
  • chronic laryngitis
  • family Hx
  • industrial exposure to carcinogens
  • nutritional deficiencies
  • HPV (common in men under 50)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

clinical manifestations of laryngeal cancer

A
  • earliest sign -> hoarseness or change in vocal quality lasting > 2 weeks
  • color changes of mouth/tongue
  • sore throat, neck pain radiating to ear
  • hemoptysis
  • swelling or lump in neck
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

late signs of laryngeal cancer

A
  • dysphagia
  • dyspnea
  • weight loss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

diagnostic tests for laryngeal cancer

A
  • indirect laryngoscopy
  • biopsy
  • CT/MRI
  • PET scan (check for metastasis)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

collaborative care for laryngeal cancer

A
  • chemo/radiation
  • hemilaryngectomy
  • supraglottic laryngectomy
  • supracricoid laryngectomy
  • total laryngectomy (will need permanent tracheostomy)
  • radical or modified neck dissection (if lymphatic spread): all tissues removed and will need reconstruction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

post op care after total laryngectomy

A
  • airway assessment and maintaining airway
  • tracheostomy care and suctioning (secretion may be blood-tinged at first)
  • tube (enteral) feedings
  • alternative communication methods
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

alternative communication methods after total laryngectomy

A
  • electrolarynx (external battery powered device)
  • transesophageal puncture: voice prosthesis placed through creation of fistula between esophagus and trachea (block stoma w/ finger to speak)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

how to care for tracheostomy

A
  • have suctioning, replacement trach tube and ambu bag at bedside
  • must stay secured
  • sterile procedure when suctioning
  • wear face shield and mask when suctioning
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

leading cause of cancer related deaths

A

lung cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

most important risk factor for lung cancer

A
  • cigarette smoking (80-90%)

- other causes: second hand smoke inhalation and other inhaled carcinogens (asbestos, radon, air pollution etc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

types of non-small cell lung cancer (NSCLC)

A
  • squamous cell (slow growing)
  • adenocarcinoma (moderate)
  • large cell (rapid; highly metastatic)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

most aggressive type of lung cancer

A

small cell lung cancer (SCLC) -> very rapid growing w/ worst prognosis;

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

characteristics of squamous cell lung cancer

A
  • second most common
  • grow in bronchial tubes
  • earlier sxs due to bronchial obstruction
  • centrally located and don’t tend to metastasize
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

characteristics of adenocarcinoma (lung cancer)

A
  • peripherally located
  • don’t see sx until widespread metastasis
  • doesn’t respond well to chemo
  • not usually related to smoking
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

characteristics of large cell carcinoma (lung cancer)

A
  • least common
  • grows in bronchi and peripherally
  • highly metastatic (sx not usually option)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

clinical manifestations of lung cancer

A
  • persistent cough w/ sputum (most common)
  • SOB
  • wheezing
  • chest pain (due to pressure on diaphragm and mediastinum
  • hemoptysis (due to tumor bleeding)
  • other less common sxs: N/V, fatigue, and anorexia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

diagnostic tests for lung cancer

A
  • Xray
  • CT
  • bronchoscopy (biopsy)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

screening guidelines for lung cancer

A

low dose CT if:

  • current smoker or smoker who has quit in past 15 years and
  • have at least 30 year pack hx and
  • receive counseling to quit smoking if current and
  • have been told by doctor about benefits, limits, and harms of screening and
  • have facility where they can go for screening
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

collaborative care for patient w/ lung cancer

A
  • surgery (not usually w/ large cell or small cell)
  • chemo/radiation
  • nutritional evaluation
  • comfort and pain control
  • adequate oxygenation of tissues
  • realistic attitude toward tx and prognosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

health promotion w/ lung cancer

A

avoid smoking (smoking cessation programs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

risk factors for cervical cancer

A
  • first full-term pregnancy at < age 17
  • > 3 full term pregnancies
  • multiple sex partners
  • HPV or chlamydia infection
  • immunocompromised
  • smoking
  • family Hx
  • low socioeconomic status
  • obesity
  • long term use of oral contraceptives
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

clinical manifestations for cervical cancer

A
  • usually asymptomatic in early stages
  • vaginal discharge (white/thick); possibly foul smelling
  • bleeding after intercourse and between periods
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

screening guidelines for cervical cancer

A
  • 21: Pap smear every 3 years
  • 30-65: pap every 3 years or pap and HPV every 5 years
  • > 65: stop screening if no lesions last 20 years
  • more often screenings if high risk or immunocompromised
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

diagnostic tests for cervical cancer

A
  • pap smear

- colposcopy and biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

prevention of cervical cancer

A
  • latex condoms
  • limiting number of sexual partners
  • HPV vaccine (Gardasil 9): recommended ages 9-14 (2 doses) or 15-26 (3 doses)
  • smoking cessation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

collaborative care for cervical cancer

A
  • laser or cryotherapy
  • conization
  • radiation/chemo
  • hysterectomy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

most common GYN cancer

A

endometrial cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

characteristics of endometrial cancer

A
  • slow growing
  • low mortality
  • 95% survival rate if local at time of dx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

risk factors for endometrial cancer

A
  • estrogen (when not counteracted by progesterone -> after menopause)
  • increased age
  • late menopause
  • nulliparity
  • obesity/smoking/DM
  • HNPCC (genetic colon cancer)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

clinical manifestations of endometrial cancer

A
  • abnormal uterine bleeding (after menopause)
  • low back pain/ABD pain (late signs)
  • signs of metastasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

screening for endometrial cancer

A

if HNPCC gene mutation -> yearly endometrial biopsy starting at age 35

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

diagnostic tests for endometrial cancer

A
  • US

- endometrial biopsy

51
Q

collaborative care for endometrial cancer

A
  • total hysterectomy w/ bilateral salpingo-oophrectomy
  • lymph node dissection
  • radiation
  • progesterone
  • chemo (advanced or recurrent)
52
Q

risk factors for ovarian cancer (most deadly of GYN cancers)

A
  • personal or family Hx of ovarian, breast or colon cancer
  • gene mutations - BRCA1 or 2 or HNPCC
  • greater number of ovulatory cycles (nulliparity or early menarche and/or late menopause)
  • HRT
  • infertility drugs
  • increase in age
  • high fat diet
53
Q

early clinical manifestations of ovarian cancer

A

vague

  • ABD discomfort
  • bloating
  • gas
  • indigestion
  • loss of appetite
  • urinary urgency or frequency
54
Q

late clinical manifestations of ovarian cancer

A
  • pain
  • bowel and bladder dysfunction
  • ascites
  • menstrual irregularities
  • weight loss or gain
  • intestinal obstructions
55
Q

diagnostic tests for ovarian cancer

A
  • pelvic exam yearly
  • US (ABD or transvaginal)
  • CA-125
  • exploratory laparotomy
56
Q

screening and prophylaxis for ovarian cancer (high-risk pts)

A
  • CA-125
  • transvaginal US
  • prophylactic oral contraceptive that contains estrogen and progestin
  • salpingo-oophrectomy
57
Q

collaborative care for ovarian cancer

A
  • total hysterectomy w/ bilateral salpingo-oophrxectomy
  • tumor debulking (palliative)
  • radiation
  • chemo (IV and intraperitoneal)
  • second look (exploratory sx 6 months after chemo/radiation to check for recurrence)
58
Q

risk factors for breast cancer

A
  • family hx (1st degree relative)
  • genetics (BRCA1 or 2)
  • increasing age (>50)
  • early menarche/late menopause
  • nulliparity
  • 1st pregnancy >30 y/o
  • Hx of breast, colon, endometrial, or ovarian cancer
  • obesity
  • sedentary lifestyle
  • ionizing radiation exposure
  • alcohol > 1 drink/day
  • HRT (estrogen/progesterone)
  • oral contraceptives (younger women)
59
Q

T/F: most women w/ breast cancer have no family hx or genetic mutation

A

True

60
Q

characteristics of ductal and lobular carcinoma (breast cancer)

A
  • non-invasive (in situ) -> can metastasize if not treated

- main metastasis through axillary lymph nodes

61
Q

characteristics of inflammatory breast cancer (IBC)

A
  • uncommon cancer
  • aggressive and rapid growing w/ high risk for metastasis (poor prognosis)
  • redness, warmth, swelling
  • orange peel skin
  • breast mass may or may not be present
62
Q

characteristics of Paget’s disease

A
  • nipple or areola lesion w/ or without breast mass
  • itching, burning, nipple w/ discharge (bloody)
  • good prognosis of confined to nipple
63
Q

clinical manifestations of breast cancer

A
  • palpable lump (hard, irregularly shaped, non- mobile, non-tender)
  • abnormality in mammogram
  • nipple discharge or inversion
  • orange peel breast skin appearance (due to plugged lymphatics)
64
Q

screening guidelines for breast cancer

A
  • 40-44 have option to start screening w/ yearly mammogram
  • 45-54 get mammogram yearly
  • 55 and older can switch to every other year or continue yearly
  • high risk: breast MRI and mammogram starting age 30
65
Q

T/F: breast exams are not recommended anymore

A

True

66
Q

diagnostic tests for breast cancer

A
  • mammogram
  • breast US or MRI
  • biopsy (definitive test)
  • sentinel (first node that would be hit by cancer) and/or axillary lymph node dissection
  • estrogen and progesterone receptor (+ is slow growing and - is fast growing and frequently reoccur)
  • HER-2, CA 15-3, CA 27-29
  • metastatic workup
67
Q

collaborative care for breast cancer

A
  • surgery (main treatment)

- radiation, chemo, hormonal therapy if estrogen receptor +, biologic and targeted therapy

68
Q

types of surgery for breast cancer

A
  • sentinel lymph node dissection (SLND)
  • axillary lymph node dissection (ALND)
  • lumpectomy
  • modified radical mastectomy
  • breast reconstruction (tissue expander; TRAM flap)
69
Q

adverse effects of breast cancer surgical therapy

A
  • lymphedema due to removal of lymph nodes (redness, edema, pressure)
  • post mastectomy pain syndrome (neuropathic pain and symptoms)
70
Q

treatment of lymphedema after breast cancer surgery

A
  • compression stockings or sleeves
  • elevation
  • diuretics
  • isometric exercises
71
Q

treatment of post mastectomy pain syndrome

A
  • gabapentin (Neurontin)
  • NSAIDs
  • lidocaine patches
72
Q

nursing care after breast cancer surgical therapy

A
  • restoring arm function (semi fowlers position w/ arm on pillow; exercises)
  • post-op pain management, post-op drains, and S&S to report
  • prosthesis after mastectomy
  • psychosocial care (body image) and sexual issues
  • NO BP, blood draws, or injections on affected arm
73
Q

characteristics of kidney cancer

A
  • arise from renal cortex or pelvis
  • renal cell carcinoma (adenocarcinoma) is most common
  • twice as common in males
  • more common in ages 50-70
74
Q

risk factors for kidney cancer

A
  • smoking (major)
  • family Hx
  • obesity
  • HTN
  • asbestos and gasoline exposure
  • cystic kidney w/ ESRD
75
Q

clinical manifestations of kidney cancer

A
  • no early sxs - many undiagnosed until cancer progressed
  • painless hematuria
  • flank pain
  • palpable mass in flank or ABD
  • weight loss, fever, HTN, anemia
  • altered lab values (BUN/Cr)
76
Q

diagnostic tests for kidney cancer

A
  • CT, US, MRI
  • angiography
  • renal biopsy (lay flat 6 hours after and monitor for hemorrhage)
77
Q

collaborative care for kidney cancer

A
  • surgical treatment
  • chemo/radiation
  • biologic and targeted therapy
78
Q

preventative measure for kidney cancer

A
  • reduce modifiable risk factors

- includes: smoking cessation, healthy weight, control BP, and reduce exposure to toxins

79
Q

surgical treatment for kidney cancer

A
  • partial or radical nephrectomy

- ablation (use of cold/heat to remove tumor)

80
Q

characteristics of bladder cancer

A
  • transitional cell carcinoma of bladder is most common
  • most common between 60-70
  • 3x more common in men
81
Q

risk factors for bladder cancer

A
  • smoking
  • exposure to dyes used in rubber
  • Actos (DM med)
  • previous radiation of pelvic area
  • arsenic in water supply
  • recurrent bladder renal calculi
  • chronic UTIs or chronic Foley catheters
82
Q

clinical manifestations of bladder cancer

A
  • painless hematuria
  • dysuria
  • urinary urgency
  • urinary frequency
83
Q

diagnostic tests for bladder cancer

A
  • urine cytology (neoplastic or atypical cells and bladder tumor antigen test)
  • CT, US, MRI
  • cystoscopy and biopsy
84
Q

collaborative care for bladder cancer

A
  • depends on stage
  • surgery
  • radiation/chemo
  • intravesical therapy (chemo or BCG infusion directly into bladder)
85
Q

surgical options for bladder cancer

A
  • TURBT - transurethral resection of bladder tumor
  • partial cystectomy
  • radical cystectomy (bladder and surrounding reproductive organs) -> ileal conduit needed
86
Q

characteristics of prostate cancer

A
  • 2nd most common cancer in men
  • androgen-dependent adenocarcinoma
  • slow growing
87
Q

risk factors of prostate cancer

A
  • age (>50)
  • ethnicity (AA) -> higher incidence, young age, and more aggressive
  • family Hx
  • diet high in fat, red meat and low in fruits/vegetables
88
Q

clinical manifestations of prostate cancer

A

early: asymptomatic

- late: BPH sxs w/ S&S of metastasis

89
Q

screening for prostate cancer

A
  • PSA and DRE
  • age 50: men should talk to HCP about pros and cons of testing
  • High risk: AA or have father or brother w/ prostate cancer before 65 (consider screening at 45)
90
Q

diagnostic tests for prostate cancer

A
  • PSA (not specific for cancer)
  • PAP (prostatic acid phosphate)
  • DRE
  • Biopsy
  • TRUS
  • metastatic workup
91
Q

collaborative care for prostate cancer

A
  • active surveillance (watchful waiting)
  • surgical therapy
  • radiation
  • chemo (if metastatic)
  • hormonal therapy (block androgen hormones to decrease growth)
92
Q

surgical therapy for prostate cancer

A
  • radical prostatectomy -> causes incontinence and ED)
  • nerve sparing procedure (only for cancer confined to prostate)
  • cryotherapy
  • orchiectomy (if metastatic; also done to reduce testosterone levels for hormone therapy -> chemical castration)
93
Q

characteristics of testicular cancer

A
  • rare but most common cancer in young males (15-44)

- median age 33

94
Q

risk factors for testicular cancer

A
  • ethnicity (most common in caucasians)
  • family Hx
  • HIV
  • undescended testes
  • orchitis
  • maternal exposure to exogenous estrogen
95
Q

clinical manifestations for testicular cancer

A
  • painless lump
  • scrotal edema
  • dull pain or heaviness
  • signs of metastasis (advanced cancer)
96
Q

screening for testicular cancer

A

monthly self exams especially if high risk

97
Q

diagnostic tests for testicular cancer

A
  • AFP
  • LDH
  • hCG
  • testicular US
98
Q

collaborative care for testicular cancer

A
  • orchiectomy
  • chemotherapy
  • radiation
99
Q

risk factors for colorectal cancer

A
  • family Hx
  • genetics (HNPCC) - 5-10%
  • obesity and physical inactivity
  • red meat and processed meat
  • alcohol/smoking
  • high fat/low fiber/low fruit and vegetable diet
  • Hx of IBD
  • 85% of all colorectal cancer arise from adenomatous polyps
100
Q

clinical manifestations of colorectal cancer

A
  • gradual onset (sxs usually present w/ cancer is advanced)
  • iron-deficiency anemia
  • ABD pain
  • rectal bleeding
  • change in bowel habits
  • bowel obstruction or perforation
101
Q

screening for colorectal cancer

A
  • age 45-75 stool based test every year OR flex sig every 5 years OR colonoscopy every 10 years or CT colonography every 5 years
  • people at increased risk might need to start screening before age 45 and be screening more often
  • age 76-85 discuss w/ HCP
  • > 85 end screenings
102
Q

diagnostic tests for colorectal cancer

A
  • DRE
  • colonoscopy
  • fecal occult blood (stool guaiac) or fecal immunochemical test
  • CEA
  • CBC
  • CT, MRI (r/o metastasis)
103
Q

collaborative care for colorectal cancer

A
  • colon resection and reanastamosis
  • chemo/radiation
  • targeted therapies
104
Q

group of malignant disorders that affects blood, blood forming tissues of bone marrow, lymph, and spleen

A

leukemia

105
Q

characteristics of leukemia

A
  • affects all age groups - 9x more common in adults (especially over age 50)
  • no single cause
106
Q

potential risk factors of leukemia

A

chemo/radiation exposure or treatment

  • viruses
  • immunologic deficiencies
107
Q

4 types of leukemia

A
  • acute myelogenous (AML)
  • acute lymphocytic (ALL)
  • chronic myelogenous (CML)
  • chronic lymphocytic (CLL)
108
Q

characteristics of AML

A
  • abrupt onset
  • common in adults
  • growth of immature leukocytes
109
Q

characteristics of ALL

A
  • abrupt (fever) on insidious onset
  • most common in children
  • growth of immature lymphocytes
110
Q

characteristics of CML

A
  • chronic stable phase -> acute aggressive phase
  • chronic phase can last several years controlled w/ tx
  • Philadelphia chromosome is diagnostic hallmark (90-95%)
111
Q

characteristics of CLL

A
  • most common in adults

- may not need tx in very early stages

112
Q

clinical manifestations of leukemia

A
  • fatigue, anorexia, weight loss, dysphagia
  • bleeding, ecchymosis, petechiae
  • fever, infections, night sweats
  • bone pain and oral lesions
  • enlargement of liver, spleen and lymph nodes
  • low, normal, or high WBCs
  • low H&H, RBCs and platelets (pancytopenia)
113
Q

diagnostic tests for leukemia

A
  • CBC w/ peripheral smear
  • bone marrow biopsy
  • uric acid levels
  • LDH
114
Q

collaborative care for leukemia

A
  • goal is remission
  • chemo/radiation
  • splenectomy
  • hematopoeietic stem cell transplant (HSCT)
  • blood and/or platelet transfusions
  • antiinfectives
115
Q

characteristics of Hodgkin lymphoma

A
  • abnormal Reed-Sternberg cells in affected lymph nodes
  • most frequent at 15-35 or >55 years
  • 80% long term survival
116
Q

risk factors for Hodgkin lymphoma

A
  • EBV
  • genetics
  • occupational toxins
  • HIV
117
Q

clinical manifestations of Hodgkin lymphoma

A
  • painless lymphadenopathy
  • progress from one group of lymph nodes to another
  • mediastinal mass
  • splenomegaly
  • ABD mass
  • fever, weight loss, night sweats, and pruritus
118
Q

diagnostic tests for Hodgkin lymphoma

A
  • CBC w/ peripheral smear

- lymph node bx and analysis -> Reed Sternberg cells

119
Q

collaborative care for Hodgkin lymphoma

A
  • main tx w/ radiation/chemo
  • HSCT
  • promote screening for secondary cancers
120
Q

characteristics of Non-Hodgkin lymphoma

A
  • diverse group of lymphomas (B cell is most common, T cell, and NK cell)
  • cause is unknown
  • usually over age 50
  • survival rate is less than Hodgkin lymphoma
121
Q

risk factors for Non-Hodgkin lymphoma

A
  • family Hx
  • chromosome translocations
  • viral infections
  • environmental agents/chemicals
  • immunosuppression
122
Q

clinical manifestations for Non-Hodgkin lymphoma

A
  • localized or generalized painless lymphadenopathy (noncontiguous spread)
  • lymph nodes enlarge over period of months to years
  • fever, night sweats, weight loss
123
Q

diagnostic tests for Non-Hodgkin lymphoma

A
  • lymph node bx

- CT and BM biopsy for staging

124
Q

collaborative care for Non-Hodgkin lymphoma

A

chemo/radiation