Care of Patients with Cancer Flashcards
cancer w/ highest incidence among women
breast cancer
cancer w/ highest incidence among men
prostate cancer
process of cancer development
- initiation
- promotion
- progression
stage of cancer development where there is a mutation of a cell’s genetic structure
initiation
what causes mutation of cell’s genetic structure
- inherited mutation (5-10%)
- exposure to carcinogens (chemical, radiation, viral)
T/F: activities of promoting factors for cancer are reversible
True
What are most cancer-related deaths in the US related to
- tobacco use
- unhealthy diet
- physical inactivity
- obesity
latent period (time between mutation in cell and actual signs of cancer)
1-40 years
stage of cancer where there is growth and invasion of tissues and tumor angiogenesis
progression
routes for metastasis
blood and lymphatics
most common sites of metastasis
- brain
- bone
- liver
- lung
- adrenal glands
antigens found on tumor cell surfaces, in tumor cells, and in fetal cells
oncofetal antigens (tumor markers)
carcinoembryonic antigen (CEA) indicates what
- colon, lung, pancreas, or breast cancer
- also seen in cirrhosis, ulcerative colitis, and heavy smokers
alpha fetoprotein (AFP) indicates what
hepatic or germ cell cancers (testicular and ovarian)
CA-125 indicates what
ovarian cancer
CA-19-9 indicates what
pancreatic and gallbladder
CA 15-3, CA 27-29, and HER-2 indicate what
breast cancer
prostate-specific antigen (PSA) indicates what
prostate cancer
characteristics of benign tumors
- well differentiated and encapsulated
- no metastasis
- rare recurrence
- expansive growth
- similar to parent cells
- slight vascularity
characteristics of malignant tumors
- poorly differentiated and non-encapsulated
- can metastasize
- possible recurrence
- infiltrative and expansive growth
- different from parent cells
- moderate to marked vascularity
purpose of cancer staging
helps determine patient’s prognosis and best treatment
TNM cancer staging
- tumor size and invasiveness
- Nodes (spread to lymph nodes)
- Metastasis
5 stages of cancer
- 0: cancer in situ
- 1: tumor limited to tissue of origin; localized tumor growth
- 2: limited local spread
- 3: extensive local spread and regional spread
- 4: metastasis
prevention of cancer
- avoid or reduce exposure to known carcinogens (smoking, alcohol, excessive sun exposure)
- eat a balanced diet
- exercise regularly
- maintain healthy weight
- adequate rest
- reduce stressors and improve coping skills
- use sunscreen
7 warning signs of cancer
CAUTION
- changes in bowel or bladder
- a sore that doesn’t heal
- unusual bleeding or discharge from any orifice
- thickening or a lump (breast or elsewhere)
- indigestion or difficulty swallowing
- obvious changes in wart of mole
- nagging cough or hoarseness
diagnostic tests for cancer
- radiologic studies
- colonoscopy or sigmoidoscopy
- laboratory tests
- biopsy