Upper and lower GI Flashcards

1
Q

What are the different types of vomiting?

A

Vomiting with retching
Projectile vomiting
Bilious vomiting
Effortless vomiting

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2
Q

What are the three phases of vomiting with retching?

A

Pre-ejection phase
Ejection phase
Post-ejection phase

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3
Q

What are the signs of the pre-ejection phase of vomiting with retching?

A

Pallor
Nausea
Tachycardia

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4
Q

What are the parts of the ejection phase of vomiting with retching?

A

Retch

Vomit

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5
Q

What can stimulate the vomiting centre of the brain?

A
Enteric pathogens
Intestinal inflammation
Metabolic derangement
Infection
Head injury
Visual stimuli
Middle ear stimuli
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6
Q
CS:
6wk boy, 3wk Hx vomiting after every feed, bottle fed 6oz 3hrly, vomitus: large volume, milky/curdy, mostly projectile
Irritable/crying
Not gaining weight adequately
O/E: slightly dehydrated

What are the differential diagnoses?

A

Gastro-oesophageal reflux
Overfeeding
Pyloric stenosis

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7
Q

What is an olive tumour?

A

Olive-shaped mass in abdomen in upper left quadrant of epigastric region

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8
Q

What is a visible sign of pyloric stenosis?

A

Visible gastric peristalsis

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9
Q

What is an olive tumour indicative of?

A

Pyloric stenosis

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10
Q

What is the vomiting like with pyloric stenosis?

A

Projectile non bilious vomiting

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11
Q

What is the management of pyloric stenosis?

A
Fluid resuscitation (for dehydration)
Refer to surgeons
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12
Q

What is the surgery for pyloric stenosis?

A

Ramstedts pyloromyotomy

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13
Q

What age does pyloric stenosis usually present?

A

4-12 weeks

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14
Q

Does pyloric stenosis usually present in boys or girls more?

A

Boys

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15
Q

What is the characteristic electrolyte disturbance of pyloric stenosis?

A

Metabolic alkalosis (↑ pH)
Hypochloraemia (↓Cl)
Hypokalaemia (↓K)

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16
Q

What are the signs of physical signs pyloric stenosis?

A

Projectile non-bilious vomiting
Weight loss
Dehydration +/- shock

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17
Q

What is bilious vomiting usually due to unless proven otherwise?

A

Intestinal obstruction

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18
Q

What are the main causes of bilious vomiting?

A
Intestinal atresia
Malrotation +/- volvulus
Intussusuception
Ileus
Crohn's disease with strictures
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19
Q

What is a volvulus?

A

When a loop of intestine twists around itself and the mesentery that supports it, resulting in a bowel obstruction

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20
Q

What is ileus?

A

Lack of movement somewhere in the intestines that leads to a buildup and potential blockage of food material

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21
Q

What is intussusception?

A

One segment of intestine “telescopes” inside of another, causing an intestinal obstruction (blockage)

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22
Q

What are the investigations for bilious vomiting?

A
Abdominal XR
Contrast meal
Surgical opinion (exploratory laparotomy)
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23
Q

What is effortless vomiting usually due to?

A

Gastro-oesophageal reflux

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24
Q

What are the cases when gastro-oesophageal reflux may not spontaneously resolve?

A

Cerebral palsy
Progressive neuro problems
Oesophageal atresia +/- TOF operated
Generalised GI motility problem

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25
Q

What are the presenting symptoms of reflux?

A
Vomiting
Haematemesis
Feeding problems
Failure to thrive
Apnoea
Cough
Wheeze
Chest infections
Sandifer's syndrome
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26
Q

What is Sandifer’s syndrome?

A

Neurological: involves spasmodic torsional dystonia with arching of the back and rigid opisthotonic posturing, mainly involving the neck, back, and upper extremities, associated with symptomatic gastroesophageal reflux, esophagitis, or the presence of hiatal hernia

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27
Q

What is the medical assessment for reflex?

A
History and exam
Video fluroscopy
Barium swallow
pH study
Oesophageal impedance monitoring
Upper GI endoscopy
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28
Q

What problems can be identified on barium swallow?

A
Dysmotility
Hiatus hernia
Reflux
Gastric emptying
Strictures
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29
Q

What are the problems with barium swallow?

A

Aspiration

Inadequate contrast taken

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30
Q

What are the positive points of videofluroscopy and barium meal?

A

May detect aspiration

Defines anatomy well

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31
Q

What are the negative points of videofluroscopy and barium meal?

A

May miss reflux

Radiation

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32
Q

What are the positive points of pH study?

A

Detects acid reflux missed by barium

33
Q

What are the negative points of pH study?

A

Only detects acid reflux

May be unpleasant for child

34
Q

What are the positive points of endoscopy?

A

Best test for oesophagitis

Can be combined with pH+ impedance study

35
Q

What are the negative points of endoscopy?

A

Needs anaesthetic

36
Q

What are the positive points of trial feeding?

A

Most physiological test

May be best discriminator if child needs surgery

37
Q

What are the negative points of trial feeding?

A

NG tube required

Needs 2-3 days in hospital

38
Q

What is the treatment for gastro-oesophageal reflux?

A

Feeding advice
Nutritional support
Medical treatment
Surgery

39
Q

What is the feeding advice for gastro-oesophageal reflux?

A

Thickeners for liquids
Appropriateness of foods: texture/amount
Behavioural programme: oral stimulation/removal of aversive stimuli
Feeding position

40
Q

What nutritional support can be given to babies with gastro-oesophageal reflux?

A

Calorie supplements
Exclusion diet (milk free)
NG tube
Gastrostomy

41
Q

What medical treatment can be given for gastro-oesophageal reflux?

A

Feed thickener: Gaviscon
Prokinetic drugs
Acid suppressing drugs: H2 receptors blockers/PPI

42
Q

What are the indications for surgery in gastro-oesophageal reflux?

A

Failure of medical treatment

Persistent: failure to thrive, aspiration, oesophagitis

43
Q

What is Nissan fundoplication?

A

A surgical procedure that corrects GERD by creating an improved valve mechanism at the bottom of the oesophagus - it is meant to prevent the flow of acids upward

44
Q

For which group of patients might surgery be more complication for those with GOR?

A

Cerebral palsy

45
Q

What is the definition of chronic diarrhoea?

A

4 or more stools a day

>4 weeks

46
Q

What is the definition of acute diarrhoea?

A

4 or more stools a day

<1 week

47
Q

What is the definition of persistent diarrhoea?

A

4 or more stools a day

2-4 weeks

48
Q

What are the three main groups of causes of diarrhoea?

A

Motility disturbance
Active secretion (secretory)
Malabsorption of nutrients (osmotic)

49
Q

What conditions come under osmotic diarrhoea?

A

Food allergy
Coeliac disease
CF

50
Q

What is the management of osmotic diarrhoea?

A

Removal of causative agent

51
Q

What conditions come under secretory diarrhoea?

A

Acute infective diarrhoea

IBD

52
Q

What is secretory diarrhoea associated with?

A

Toxin production

53
Q

What conditions can cause motility diarrhoea?

A

Toddler’s diarrhoea
IBS
Congenital hyperthyroidism
Chronic intestinal pseudo-obstruction

54
Q

What is inflammatory diarrhoea?

A

Malabsorption due to intestinal damage

Accelerated transit time in response to inflammation

55
Q

Which type of diarrhoea has a larger volume: osmotic or secretory?

A

Secretory

56
Q

Which type of diarrhoea stops in response to fasting?

A

Osmotic

57
Q

Which diseases cause fat malabsorption and diarrhoea?

A
Pancreatic disease (CF)
Hepatobiliary disease
58
Q

What are the signs and symptoms of coeliac disease?

A
Abdominal bloatedness
Diarrhoea
Failure to thrive
Short stature
Constipation
Tiredness
Dermatitis herpatiformis
59
Q

What are the screening tests for coeliac disease?

A

Serological screens
Duodenal biopsy
Genetic testing

60
Q

What are the serological screens for coeliac disease?

A

Anti-tissue transglutaminase
Anti-endomysial
Anti-gliadin
IgA dependent test

61
Q

How would you diagnose children with coeliac disease with the ESPGHAN guidelines?

A

Symptomatic
Anti TTG >10 times upper limit of normal
Positive anti-endomysial antibodies
HLA DQ2, DQ8 positive

62
Q

What is the treatment for coeliac disease?

A

Gluten-free diet for life

63
Q

What questions should you ask about constipation?

A

How often?
How hard?
Is it painful?
Has there been a change?

64
Q

What type on the Bristol stool chart are constipated?

A

Type 1 & 2

65
Q

What are other signs/symptoms of constipation?

A
Poor appetite
Irritable
Lack of energy
Abdominal pain/distention
Withholding or straining
Diarrhoea
66
Q

Why do children become constipated?

A
Social:
- Poor diet, too many fluids/milk
- Potty training/school toilet
Physical
- Intercurrent illness
- Medication
FH
Psychological
Organic
67
Q

What diet measures can treat constipation?

A

Increase fibre, fruit, vegetables, fluids

Decrease milk

68
Q

What psychological factors can treat constipation?

A

Reduce aversive factors - height, cold, school

Reward good behaviour

69
Q

What are the different types of laxative that soften stool and stimulate defecation?

A

Osmotic laxatives - lactulose
Stimulant laxatives - senna, picolax
Isotonic laxatives - movicol

70
Q

What is the treatment of impaction?

A

Empty impacted rectum/colon
Maintain regular stool passage
Slow weaning off treatment

71
Q

What are more common presenting symptoms in UC than Crohn’s?

A

Diarrhoea and rectal bleeding

72
Q

What are symptoms of Crohn’s and UC?

A
Diarrhoea
Rectal bleeding
Abdo pain
Fever
Weight loss
Growth failure
Arthritis
73
Q

What are more common presenting symptoms in Crohn’s than UC?

A

Weight loss

Growth failure

74
Q

What are the investigations for IBD?

A

FBC & ESR
Stool calprotectin
CRP

75
Q

What are you looking for the in FBC of someone with IBD?

A
Anaemia
Thrombocytosis
Raised ESR
Raised CRP
Low albumin
Raised calprotectin
76
Q

What are imaging investigations for IBD?

A

MRI
Barium meal
Endoscopy

77
Q

What are the aims of treatment in IBD?

A

Induce and maintain remission
Correct nutritional deficiencies
Maintain normal growth and development

78
Q

What the methods of treatment for IBD?

A
Medical:
- anti-inflammatory
- immuno-suppressive
-  biologicals
Nutritional:
- immune modulation
- nutritional supplementation
Surgical