UNIT3 AOS1 Flashcards
What is primary structure?
Sequence of amino acids in a polypeptide chain
(peptide bonds)
What is secondary structure?
Involves the folding of polypeptide chains into alpha helices, beta pleated sheets and random coils
(hydrogen bonds)
What is tertiary structure?
Involves more folding and the overall 3D structure of the protein
(R-group bonding of amino acids such as hydrogen, desulfide and ionic bonding)
What is quaternary structure?
Proteins composed of two or more polypeptide chains
Why is DNA considered redundant?
The same amino acid can be selected using a variety of codons
What role does CRISPR-Cas9 complex naturally play in bacteria?
Cuts the DNA of invading viruses, preventing them from damaging the bacterium
What modifications occur to the RNA transcript in humans before it leaves the nucleus
Introns removed
Methyl cap added
Poly A tail added
What does CRISPR stand for?
Clustered Regularly Interspaced Short Palindromic Repeats
What is Cas9?
An RNA guided DNA endonuclease, an enzyme that cuts DNA at sequence that is complementary to RNA in the enzyme
What is the PAM sequence?
A short sequence of nucleotides (2-6) that Cas1 and Cas2 can consistently recognise
What does PAM stand for?
Protospacer Adjacent Motif
Where are anticodons found?
Transfer RNA