Unit I - Pharmacology & Cognition Flashcards
1
Q
3 Types of Anti Depressants
A
- Tricyclic
- MAOI
- SSRI
2
Q
Tricyclic Anti Depressants
A
Blocks the absorption of serotonin
- Nopramin
- Elavil
- Anafranil
- Tofranil
- Anticholinergic S/S - dry mouth, urine retention, constipation, blurred vision, tachycardia, excess perspiration
- Weight gain
- Extreme caution in asthma patient, cardiovascular/GI disorders, alcoholism, shizophrenia and bipolar disorders
3
Q
MAOI
A
Increases # of neurotransmitters by inhibiting reabsorption
- Nardil
- Parnate
- Avoid tyramine in food and beverages - can cause hypertensive crisis
- Aged foods - cheese, beer, pizza, wine, salami
- Low safety margin - used for patients who don’t respond to SSRI and TCA
4
Q
Selective Serotonin Reuptake Inhibitors
A
Inhibits serotonin
- Prozac
- Paxil
- Zoloft
- Break between MAOI and SSRI
- Wait two weeks after stopping MAOI, before starting SSRI
5
Q
Atypical Anti-Depressants
A
- Wellbutrin
- Effects activity of NE and DA
- Use cautiously in patients with seizure disorders
- Lowers seizure threshold
- Effexor
- Available in immediate or XR form
6
Q
Traditional Antipsychotics
A
- Kills all dopamine overload
- Sedates patient
- Causes gynocomastia
- Avoid alcohol, drugs, caffeine, smoking
- Photosensitivity
- Anticholinergive S/S
- Haldol
- Thorazin
- Prolixin
- Navane
7
Q
Atypical Antipsychotics
A
- Current meds of choice for psychotic disorders
- Generally treat negative and positive symptoms
- Geodone
- Risperdal
- Use sunscreen, prevent photosensitivity
- Avoid extreme temp
- Itching/srash, decreased libido, dysmenorrhea, rhinitis, cough
- Abilify
- Tachycardia, fever, sedation, headache, N/V, parkinsonism
- Zypyrexa
- Oral disintegrating tablets contain aspartame
- Agranulocytosis, ambylopia, increased liver enzymes
8
Q
Clozapine
(Clazaril)
A
- No class
- Treats schizophrenia
- Used when schizo is unresponsive to standard therapy with other anti-psychotics
- Reduces suicidal behavior
- S/S - DASHN
- Drooling
- AGRANULOCYTOSIS - wipes out immune system, why you need weekly blood tests
- Sedation
- Hypotension (orthostatic)
- Not for dementia patients
9
Q
Anxiolitics
A
- Think benzo’s.
- Treats anxiety disorders
- Habit forming, OD can be fatal
- Used for short term, can be addictive
- Valium
- Xanax
- Ativan
- Kloponin
- Others - Versed, Restoril, Serax
10
Q
Mood Stabilizers
A
- Treats bipolar/unipolar disorders
- Bipolar patient with anti depressant takes a mood stabilizer at the same time to prevent manic episode
- Don’t change diet or decrease fluid intake
- No alcohol, OTC, prescription meds or herbs w.o. notifying HCP
- Lithium
- Depakote
- Carbamazepin
- Trileptal
11
Q
Anticholinergics
A
- Block acetylcholine
- Dry mouth/nose/throat, constipation, drowsiness, blurred vision, constipation, memory loss
- Given for negative effects of antipsychotics
- Cogentin
- Artane
- Benadryl
12
Q
Medication s/s r/t Antipsychotics
A
- Akathisia
- Tardive Dyskinesia
- Acute Dystonia
- Neuroleptic Malignant Syndrome
13
Q
Akathisia
A
- Restless leg syndrome
- Involuntary movement of lower legs
- Uncontrollable
- Urge/need to move legs to prevent unpleasant sensations
14
Q
Tardive Dyskinesia
A
- Caused by longterm use of neuroleptic meds (Haldol, Thorazine)
- Involuntary movements of tongue, lip, face, trunk, extremities
- Permanent, no treatment
15
Q
Acute Dystonia
A
- Sustained muscular spasms
- Abnormal postures
- Treatment - IM Anticholinergics