Unit Exam 1 Flashcards
Are Dependent on dynamic processes that are crucial for life and homeostasis
Fluid and electrolyte balance
Plasma composed of how many percent
92%
Body fluid is located into fluid compartments
Intracellular space and extracellular space
2/3 of body fluid is in the
Intracellular fluid (ICF)
1/3 of body fluid is in the
Extracellular fluid (ECF)
The ECF compartment is further divided into
Intravascular, interstitial and transcellular fluid
Space that contains plasma, the effective circulating volume
~3L of the average 6L of blood volume in adults is made up of plasma
Intravascular space
A space that contains the fluid that surrounds the cell and totals about 11 to 12 L in an adult
Interstitial space
A space that is the smallest division of the ECF compartment and contains approximately 1 L
Transcellular space
What are the two major compartments
ICF and ECF
Sodium, potassium, calcium, magnesium, and hydrogen ions
Major cations in the body
Chloride, bicarbonate, phosphate, sulfate and negatively charged protein ions
Major anions in the body
The diffusion of water caused by fluid and solute concentration gradients is known as
Osmosis
Is the number of Miliosmoles of solute per kilogram of solvent
Osmolality
Is the number of Miliosmoles per liter of solution
Osmolarity
Is the pressure exerted by fluid on the walls of the blood vessel
Hydrostatic pressure
Is the pressure exerted by the solute’s with in the plasma
Osmotic pressure
Is fluid consisting of non-soluble substances that are evenly distributed within a solvent
Colloid
Are mineral ions dissolved in water
Crystalloid solutions
Normal Saline (0.9 % NaCl)
Half Normal Saline (0.45 % NaCl)
Lactated Ringer’s solution (Plasma-Lyte)
Examples of crystalloid solutions
Albumin Solutions
Hyperoncotic starch
Dextran
Examples of colloid solutions
Is the ability of solutes to cause an osmotic driving force that promotes water movement from one compartment to another
Tonicity
Are composed of 0.9% NaCl
The same sodium and chloride concentration as the bloodstream and the same water concentration as the bloodstream
Do not provoke water movement between ICF or ECF compartments
Expand the plasma volume of the blood
Isotonic solutions
Are composed of less sodium chloride concentration compared to the blood
0.45% NaCl or 0.225% NaCl
Contain less solute but more water than the bloodstream
Hypotonic solutions
Are composed of greater concentration of NaCl Compared to blood
Contain more solute concentration and less water than the bloodstream
Hypertonic solutions
Is the increase in urine output caused by the excretion of solutes such as glucose or mannitol
Osmotic diuresis
Is a laboratory value that measures the amount of urea in the bloodstream 
BUN
Is a breakdown Product of muscle metabolism that is almost totally cleared from the bloodstream and excreted by the kidneys
Creatinine
Measures the percentage of red blood cells
Hematocrit
Is the rapid loss of body weight due to the loss of either water or sodium 
Dehydration
Other term for hypovolemia
Fluid volume deficit
Occurs when loss of ECF volume exceeds the intake of fluid
Hypovolemia
Normal BUN to and creatinine concentration ratio
10:1
Refers to an expansion of the ECF caused by the abnormal retention of water and sodium in approximately the same proportions in which they normally exist in the ECF
Hypervolemia or FVE
The most abundant electrolyte in the ECF
Sodium
Normal values of sodium
135-145 mEq/L
Earliest manifestation of hypovolemia
Thirst
What is CVP
Central venous pressure
Normal CVP
8-12 mmHg
It is the pressure of your vena cava; reflects your right atrium perfusion
CVP
What should you give If the patient experiencing cramping during dialysis
Give Chippy or food that is high in sodium
An emergency situation where the heart is unable to pump enough blood to the body due to significant blood or other fluid loss
Hypovolemic shock
Where is the site of absorption of potassium in the body
Small intestine (duodenum)
Site of obstruction of sodium in the body
jejunum
Other term for generalized edema
Anasarca
Medical term for swelling brought on by fluid entrapment in human tissues
Edema
Famous colloid solutions
BLOOD BYPRODUCT
-Fresh whole blood
-Platelet concentration
-Plasma expander
Give crystalloid when patient is
Unable to eat and cannot absorb food
Water intoxication
Consumes too much water without electrolytes
Dilutional Hyponatremia
3 factors that lead to hyponatremia
Excessive diarrhea
Excessive vomiting
Diaphoresis
What is ICP
intracranial pressure
How to determine hyponatremia
Diagnostic test:
BUN
Potassium
Calcium
Magnesium
Phosphate
How to treat hyponatremia
Give hypertonic solution 
contraindicated for patients with seizure
Vaprisol
Safe to give to Seizure patients
tolvaptan
Prominent cause of hypernatremia
Crackles
Normal value of Potassium
3.5-5.0 mEq/L
Three components of sweat
Sodium
Potassium
Chloride 
Accounts 98% in ICF
2% in ECF
Potassium
Percent of potassium excreted daily
80%
Potassium imbalances that is caused from medications
NSAIDS and ACE inhibitors
Normal Value of Calcium
8.5-10.2 mEq/L
Normal Value of Magnesium
1.3-2.3 mEq/L
Magnesium salt includes
Calcium Oxide
Normal Value of Phosphorus
2.5-4.5 mEq/L
Normal Value of Chloride
97-107 mEq/L
Major anion in ECF
Chloride
pH
7.35 - 7.45
Acid < > Alklaline
PaCO2
35 - 45 mmHg
Alkaline < > Acidosis
HCO3
22 - 26 mEq/L
Acid < - > Alkali
Two problems in hypovolemia
Sodium and potassium
Responsible for stress responses
Adrenal
The specific urine gravity of hypovolemia increases or decreases?
Increases
A good provider of sodium balance
Adrenal
HYPOVOLEMIA:
BUN + Creatinine ratio
High; 1:1
HYPOVOLEMIA:
Hematocrit is…
Declined
Major electrolyte inside and outside
Sodium and potassium
Hypovolemia Gerontologic Considerations
I and O
-1000 ml intake; output 980-1000 ml
Weight
Filling of the veins assessment
Functional ability
Verbalization of feelings
Fluid intake
What solution expands plasma volume
Isotonic solution (LR and 0.9% NaCl)
HYPOVOLEMIA:
What is your first line of defense if there is an increased blood pressure 
LR and 0.9% NaCl
What solution would you give if blood pressure is within normal limits
0.45% NaCl
Restlessness, Agitation, anxiety, Pallor, Clammy skin
Compensated shock
Alterations in mental status
Tachycardia
Tachypnea
Labored and irregular breathing
Week to absent peripheral pulses
A decrease in body temperature
Cyanosis
Decompensated shock
A shock that is in Terminal stage
Compensatory mechanism is failed
Irreversible shock
A mask that is good for emergency situation
Rebreather mask
Retains water and sodium that cause swelling
Hypervolemia
Medication that causes edema
Nephrotoxic medication
NSAIDs
Corticosteroid
Antihypertensive medication
This is to generate the oncotic pressure to prevent swelling in spaces
Expander or 20% human albumin
What do you mean by settling of blood
Set aside the blood in room temperature aron mosaka ang plasma
What type are electrolytes
Isotonic
Decrease in sodium and extra cellular spaces
Aldosterone deficiency
ICP normal Value
10 to 20 mmHg
Why is water supplement avoided
To prevent congestion of lungs
2 T as Early signs of hypernatremia
Elevated temperature
Elevated thirst
Late signs of hypernatremia
Cognitive impairment
Medical management for hypernatremia
-Hypotonic solution (or isotonic D5W When water is replaced alone)
-Diuretics
-Desmopressin

Fatigue
Sluggish bowel syndrome or decreased bowel mobility
Paresthesia
Ventricular asystole or flatline
Clinical signs of hypokalemia
Conventional treatment for hypokalemia
Daily diet intake
Oral potassium
If hypokalemia is not treated with conventional treatment
Have an IV replacement therapy
Do not give IV push when giving potassium instead…
Use infusion pump
First assessment for hyperkalemia
ECG
Emergency drug for hyperkalemia
Calcium gluconate
ECG 
Atrial depolarization
Ventricular depolarization
Atrial repolarization
Ventricular repolarization
Calcium percentage
99% located in skeletal system long bones and teeth
1% skeletal calcium
Emergency drug for hypercalcemia
Calcitonin
Hypocalcemia is prone to
Elderly people
—because of decreased calcium and prolonged bed rest
Early signs of hypocalcemia
Tetany (Chvostek & Trousseau)
Torsades de pointes means
Tachycardia or fast heart rhythm
Pharmacological treatment for hypocalcemia
Calcium chloride
Calcium gluconate
What should not be given to hypocalcemia patients
0.9% sodium chloride
Develop renal stones inside the kidneys

Hypercalcemia
Common predisposing factors of hypercalcemia
Grave’s disease
Malignant bone tumor