UE 3 Flashcards
known as the upper airway, warms and filters inspired air so that the lower respiratory tract (the lungs) can accomplish gas exchange or diffusion.
Upper Respiratory Tract
Upper airway structures consist of
the nose; paranasal sinuses; pharynx, tonsils, and adenoids; larynx; and trachea.
performs this function by facilitating life-sustaining processes such as oxygen transport, respiration, ventilation, and gas exchange.
Respiratory system
➔ Oxygen is supplied to, and carbon dioxide is removed from, cells by way of the circulating blood through the thin walls of the capillaries.
➔ Oxygen diffuses from the capillary through the capillary wall to the interstitial fluid.
➔ it diffuses through the membrane of tissue cells, where it is used by mitochondria for cellular respiration.
➔ The movement of carbon dioxide occurs by diffusion in the opposite direction—from cell to blood
Oxygen Transport
The movement of air in and out of the airways continually
replenishes the oxygen and removes the carbon dioxide
from the airways and the lungs. This whole process of gas
exchange between the atmospheric air and the blood and
between the blood and cells of the body is called
Respiration
The goals of respiration are to
provide oxygen to the tissues and to remove carbon dioxide
Respiration is divided into:
● Pulmonary ventilation
● Diffusion
● Transport of oxygen
To achieve these goals of respiration, we should have:
● Efficient respiratory pump
● Efficient heart and circulatory system
● Efficient respiratory control
Mechanisms of Pulmonary Ventilation
Lungs can expand and contract in ways
Gas Transport
Oxygen Transport
Lungs can expand and contract in ways:
- Downward and upward movement of the diaphragm to
lengthen or shorten the chest cavity - Elevation and depression of the ribs to increase and
decrease the anteroposterior diameter of the chest cavity
● Inhaled: oxygen – contract of diaphragm → downward
● Exhaled: carbon dioxide – diaphragm relaxed
oxygen and carbon dioxide carried between the
lungs and body cells by the blood
These gasses can be:
1. Dissolve the blood plasma
2. Chemically combined with other atoms or molecules
present in the blood
Gas Transport
- Loosely binding to the iron present in the protein
hemoglobin in the red blood cells creatinine.
Oxygen transport
➔ requires movement of the walls of the thoracic
cage and of its floor, the diaphragm.
➔ When the chest wall and the diaphragm return to their
previous positions (expiration), the lungs recoil and force
the air out through the bronchi and the trachea.
➔ Inspiration occurs during the first third of the respiratory
cycle; expiration occurs during the latter two-thirds.
Ventilation
Inspiration occurs during
the first third of the respiratory cycle
expiration occurs during
the latter two-thirds.
this phase of respiration normally requires energy
Inspiratory phase
this phase is normally passive, requiring very little energy
Expiratory phase
Physical factors that govern airflow in and out of the lungs
are collectively referred to as
the mechanics of ventilation
Physical factors that govern airflow in and out of the lungs
are collectively referred to as the mechanics of ventilation
and include air pressure variances, resistance to airflow,
and lung compliance
★ During inspiration, diaphragm contract
★ Thoracic Rib cage increases
★ Thorax Pressure decreases
★ After inspiration, the diaphragm recoils
movements of the diaphragm and intercostal muscles enlarge the thoracic cavity and thereby lower the pressure inside the thorax to a level below that of atmospheric pressure. As a result, the air is drawn through the trachea and the bronchi into the alveoli.
Inspiration
the diaphragm relaxes and the lungs recoil, resulting in a decrease in the size of the thoracic cavity. The alveolar pressure then exceeds atmospheric pressure, and air flows from the lungs into the atmosphere.
Expiration
● MEDULLA OBLONGATA and PONS
● CCR- CO2 and hydrogen level s
● PCR- Ph and level of O2 and CO
Brain
● DETERMINES THE CO2
● (INCREASED CO2, DECREASED PH)
● (DECREASED CO2- INCREASED PH)
Lungs
BOTH MAINTAIN THE RATIO OF CARBONIC ACID
Brain and Lungs
- LUNGS ELIMINATE CARBONIC ACID “BLOWING CO2, CONSERVE CO2 BY SLOWING VOLUME & REABSORB HCO3)
- KIDNEYS EXCRETE MORE BICARBONATE
Compensatory Mechanism
● 98% oxygen transport
○ Oxygen bound w/ hemoglobin
● If hemoglobin is saturated → deoxygenated blood
● ↑ acidity, temperature, partial pressure of carbon
dioxide
○ Oxygen is an area for respiration
Hemoglobin
● Plasma is 7%
● Hemoglobin is 15%-25%
● Bicarbonate Ion is 70%
● Transport via plasma
Carbon dioxide
● Muscle cramps, palpitation, confusion, loss of
consciousness
● High carbon dioxide in the body
● Transport via bicarbonate ions
○ CO2 diffuse in alveoli, ↓ partial pressure of
CO2 in plasma
Ammonia
ABG
➢ Respiratory Acidosis - kidney retain more HCO3, ↑ pH
➢ Respiratory alkalosis – kidney excrete more HCO3, ↓ pH
➢ Metabolic Acidosis – lugs blow off CO2, ↑pH
➢ Metabolic Alkalosis – lungs retain CO2, ↓ pH
The process in which blood is forced to flow through a
network of microscopic vessels within biologic tissue,
allowing the exchange of oxygen and other molecules
across semipermeable microvascular walls.
Pulmonary Circulation
blood is forced to flow to exchange oxygen across the
semipermeable microvascular wall
Perfusion
● conducting airways
● the systemic vascular supply to the lung and supplies
blood to conducting airways down to the level of the
terminal bronchioles as well as nerves, lymph nodes,
visceral pleura, and the walls of large pulmonary
vessels.
Bronchial Circulation
● system supply to the lungs
● ↓ pressure system
● ↑ alveolar pressure “narrow”
● ↓ alveolar pressure “decreases” converting energy
● Process of gravity
Pulmonary Circulation
● Release energy and convert energy and stored ATP
molecules
Cellular Respiration
3 Stages of Cellular Respiration
- Glycolysis
- Kreb’s Cycle
- Electron Transport Chain
● The liver converts fat to sugar
● Does not require oxygen (anaerobic)
● The cytosol of cytoplasm converts glucose
Glycolysis