Unit 6 - topic 5 Flashcards
gene expression
prokaryotes and eukaryotes must be able to regulate which genes are expressed at any given time
genes can be turned
“on” or “off” based on environmental and internal cues
on/off refers to
whether or not transcription will take place
allows for cell specialization
operons
group of genes that can be turned on or off
operons have
three parts
promoter
where RNA polymerase can attach
operator
on/off switch
genes
code for related enzymes in pathway
operons can be
repressible or inducible
repressible (on/off)
transcription is usually ON, but can be repressed (stopped)
inducible (off to on)
transcription is usually OFF, but can be induced (started)
regulatory gene
- produces a repressor protein that binds to the operator to block RNA polymerase from transcribing the gene
- always expressed, but at low levels
- binding of a repressor to an operator is reversible
allosteric activator
substrate binds to allosteric site and stabilizes the shape of the enzyme so that the active sites remain open
allosteric inhibitor
substrate binds to allosteric site and stabilizes the enzyme shape so that the active sites are closed (inactive form)
inhibitor/respressor
allosteric site