Unit 6 - Gene Expression and Regulation - topic 1 Flashcards
in the 1950’s Rosalind Franklin performed _______ of DNA
X-Ray Crystallography
Edwin Chargaff found that
amount of adenine = amt of thymine
amount of cytosine = amt of guanine
purines
double ring structure
A, G
pyrimidines
single ring structure
C, U, T
hydrogen bonds
what base pairs are held together by
adenine and thymine have
two hydrogen bonds
cytosine and guanine have
three hydrogen bonds
Rosalind Franklin found
helix shape
Chargaff found
base pairing
Watson and Crick combined the findings of Franklin and Chargaff to create the first
3D double helix model of DNA
DNA is a
double stranded helix
backbone
sugar-phosphate
DNA strands are
antiparallel
one strand runs 5’ to 3’, other runs in opposite (3’ to 5’)
5’ end
free phosphate group
3’ end
free hydroxyl group