Unit 5 Flashcards
recognized to cause disease in healthy person
true pathogens
microorganisms that dont usually produce disease but are capable
opportunistic pathogens
the easiest and most frequent traveled portal of entry
respiratory tract
portal of entry through food, water and contaminated fingers
gastrointestinal tract
portal of entry via sexual activity
genitourinary tract
an important defense against disease
skin
punctures, injections and wounds
parenteral route
produce all the signs and symptoms of the disease when swallowed
salmonella typhi
cause adherence to epithelial cells
lipoteichoic acid and protein f
heat-resistant and acid-resistant protein
m protein
outer membrane protein used to attach to cells
opa
resists the host’s defenses by impairing phagocytosis
capsule
bacterial enzymes that coagulate the fibrinogen in blood
coagulase
break down fibrin and thus digest clots formed by the body to isolate the infection
kinase
facilitates the spread of gas gangrene
collagenase
destroys antibodies
IgA protease
hydrolyzes hyaluronic acid
hyaluronidase
are poisonous substances produced by pathogenic microorganisms
toxins
ability to produce toxic substances
toxigenicity
Corynebacterium diphtheriae
diphteria toxin
inactivates elongation factor for protein synthesis
diphteria toxin
Pseudomonas aeruginosa
exotoxin a
manifestation of exotoxin a
skin infections, sepsis and pneumonia
manifestations of diphteria toxin
swollen lymph nodes and sore throat
higher or lower than normal
temperature
may have signs and symptoms of an infection
infection
confused, sleepy, difficult to rouse
mental decline
severe pain, discomfort and shortness of breath
extremely ill
when it comes to sepsis, remember
its about time
shigella
shiga toxin
binds to 60s ribosome in cells and removes a specific adenine residue
shiga toxin
manifestation of shiga toxin
diarrhea
escherichia coli
heat labile toxin
activates adenylate cyclase
heat labile toxin
activates guanylate cyclase
heat stable toxin
bacillus anthracis
edema toxin, lethal toxin
bacillus anthracis makes three proteins:
protective antigen, lethal factor and edema factor
manifestation of edema toxin, lethal toxin
woolsorter’s disease
vibrio cholerae
cholera toxin
bordetella pertussis
pertussis toxin
manifestation of pertussis toxin
whooping cough
clostridium tetani
tetanospasmin
inhibits inhibitory neurons
tetanospasmin
clostridium botulinum
botulinum toxin
inhibits the release of acetylcholine
botulinum toxin
manifestation of botulinum toxin
floppy baby
clostridium perfringens
alpha toxin
manifestation of alpha toxin
gas gangrene