Unit 4.3 Monoclonal antibodies triple Flashcards
monoclonal antibodies are
identical antibodies (single type) produced by a hybridoma
Which cells are used to make a hybridoma?
tumour cell and a B lymphocyte
What is the spleen?
an organ in the abdomen that contain antibody producing WBC
What is a myeloma cell
a white blood cell that has turned cancerous
what special feature of the myeloma is useful
it will grow and divide indefinitely
An antigen is
a protein molecule on the surface of cells
A lymphocyte is
an immune cell
An antibody is
protein Y shaped molecule specific to an antigen (on a pathogens surface)
What cell produces antibodies?
B lymphocytes (plasma cells)
What are monoclonal antibodies used for?
diagnosis (e.g. pregnancy test) or medical treatment (cancer)
mono means
one
clonal means
identical copies of
What is the first step in monoclonal antibody production?
inject a mouse with the desired antigen
When a mouse is injected with an antigen, how will it respond?
by producing antibodies against the antigen
What do scientists do with the myeloma and the antibody producing B lymphocyte?
fuse them together to create a hybridoma
