unit 4 Flashcards

(43 cards)

1
Q

evolutionary arms race

A

pathogens influencing the evolution of their hosts and hosts influencing the evolution of pathogens.

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2
Q

types of defenses in immune system

A

Physical barriers
chemical defenses
cellular defenses
inflammatory response
behavioral

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3
Q

innate immunity

A

something animals are born with.
Humoral (fluids) innate immunity involves various substances found in body fluids that interfere with pathogen growth or clump pathogens together for easy disposal.
Cellular innate immunity involves cells called phagocytes that “eat” pathogens and by natural killer cells that destroy abnormal body cells.

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4
Q

acquired (adaptive) immunity

A

recognizes and destroys pathogens that the immune system has encountered before.
This system “learns” to recognize a pathogen’s antigens, such as toxins or proteins the pathogen produces.
Provides a sort of immunologic memory so that the body can fight off a pathogen better in the future.

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5
Q

innate physical defenses

A

integuments and mucous membranes are the first barrier to invading organisms.

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6
Q

innate chemical defenses

A

antimicrobial substances that inhibits pathogen growth
Lysozyme attacks the cell wall of many bacteria.
Cytokines are a class of molecules that are used for cell signaling. (They tell neighboring or distant cells to initiate an immune response.)

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7
Q

innate chemical defenses: Antimicrobial peptides AMPs

A

short chains of amino acids
- Attach to cells and make holes in membranes.
- May also work as cell signaling molecules between host cells.

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8
Q

innate chemical defenses: pattern recognition receptors

A

proteins on the surface of innate immune cells that detect non-specific antigens
mediate initiation adaptive immunity + inflammatory cytokines

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9
Q

complement system (small proteins in blood)

A

cleave proteins + release cytokines
activation results in phagocyte attraction/stimulation, inflammation and attack on invader

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10
Q

Cellular Innate defenses: Phagocytosis

A

A phagocytes is a type a white blood cell
involves invaders, old cells, debris
phago engulfs and lysosomes digest
phago presents receptor for antigens called MHC that activates acquired immune

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11
Q

immunity in invertebrates

A

xenograft- different species and allograft- same species

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12
Q

inflammation

A

innate response to pathogens, damaged cells, or irritants.
Involves immune cells (white blood cells), blood vessels, and molecular mediators.

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13
Q

5 cardinal signs of inflammation

A

Redness, Heat, swelling, pain, loss of function

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14
Q

Inflammation process

A

starts with immune cells present: phagocytes/white blood cells (macrophages, dendrite, mast)
PRR recognize PAMP, cell activates mediators (histamine, prostaglandin) complementary system is highly active

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15
Q

Inflammation fibrosis

A

inflammation failed to clear invader, starts walling off site to stop damage
granulomas may surround and suffocate

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16
Q

signs of more severe inflammation

A

Necrosis, Ascesses, ulcers

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17
Q

Acquired immune response in vertebrates

A

non self recognition can resist foreign and invader substances
stimulated by Antigen (usually proteins)
made of humoral and cellular immunity (just like innate)

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18
Q

Major Histocompatibility Complex MHC

A

act like name tags the name being peptide bits
when immune system reads this foreign “name” triggers an attack

19
Q

recognition molecules

A

MHC are not the actual receptor just the display
antibodies and T-cells are the molecules
wide variety each with a different antigen receptor

20
Q

Acquired immunity: lymphocytes

A

these are white blood cells primary comp
lymphocytes + RBC come from stem cells in bone marrow

21
Q

Acquired immunity : B cells

A

B; mature in bone marrow, release in blood/lymph (body fluid)
membrane bound antibodies bind to antigen
memory B cells = copies of original in high concentration

22
Q

Antibodies : Immunoglobulins

A

location: surface of B cells or secreted by plasma cells derived from B cells
The amino acid sequence near the ends of the Y varies in both chains bc it forms a cleft, making them specific to an antigen called the antigenic binding site.

22
Q

Acquired immunity : T cells

A

T; mature in thymus gland
go through a lot of gene recombination during growth for diversity in receptors
T cells can only recognize antigens that bound to MHC on other cells

23
Q

Cell mediated v. humoral immunity

A

Cell-mediated immunity: on the other hand does not depend on antibodies for its adaptive immune functions and is primarily driven by mature T cells, macrophages and the release of cytokines in response to an antigen.

Humoral immunity: produces antigen-specific antibodies and is primarily driven by B cells.

24
Antibody in host defense
particles become coated and stimulates macrophages (type of phagocyte) can prevent binding to target cells activation of complement antibody-dependent cell mediated cytoxicity (contact killing of invader)
25
comparative psychology v. ethology
CP: focuses on a few species studied in a lab setting (e.g. lab rats) Ethology: the study of animal behavior in its natural habitat.
26
behavioral ecology v. sociobiology
behavioral: focuses on individual behavior that maximizes reproductive and evolutionary success and studies mate choice, foraging, parental investment, Socio: is the ethological (under natural conditions) study of social behavior
27
Tinbergens Four questions
Proximate (how behavior occurs): 1. mechanism/casuation; what stimulus? 2. ontogeny/development; behavioral change through life? Ultimate (why behavior occurs): 3. function/adaptation; help survive/reproduce? 4. phylogeny/evolution; how ancestors contribute?
28
Stereotypical behaviors (innate)
predictable sequences with low variation don't have to learn, and tend to be key to survival ex; egg rolling of the goose
29
genetics of behavior
very complex and involves many genes some show simple mendelian honeybees; hygienic bees uncap rotten diseased larvae certain passed alleles are consistent w this
29
Sign Stimuli response
when animal responds to one specific aspect of stimulus ex; stickleback fish and robins only aggress towards red stripe despite shape
30
Learning : diversity of behavior
modification of behavior through experience behaviors have been traced to nervous pathways, connecting sensory neurons to motor neurons that control the withdrawal muscles. Repeated prodding is associated with reduced release of neurotransmitters
31
social behavior
reciprocal communication in a cooperative nature that allows a species to organize 4 pinnacles
32
benefits of sociality
provide defense/protection (safety in numbers) synchs reproductive behavior hunting for food division of labor learning
33
culture
process involving the social transmission of novel behaviors or ideas (memes), both among peers and between generations.
33
33
aggression v. Agonistic
Aggression: is narrowly defined as an offensive physical action, or threat Agonistic behaviors: are a broader category including any activity related to fighting
34
ritualization
involves a behavior that has been modified through evolution to make it effective in serving a communicative function involve ritual jousts: fiddler crab claw battles if dominance is not established = violence (seals)
35
territoriality
A territory is a fixed area whose occupant excludes intruders of the same species and sometimes other species.
36
inclusive fitness
relative number of an individual’s alleles that are passed on to future generations from one’s own offspring and that of related individuals.
37
reciprocal altruism
temporarily reduces its fitness while increasing another organism's fitness, with the expectation that the other organism will act in a similar manner at a later time
38
what is cognition
process of acquiring knowledge and understanding through thought, experience, and the senses. "to know things "
39
what is intelligence
the ability to think, to learn from experience, to solve problems, and to adapt to new situations "to use what you know the right way"