Unit 3 pyruvate oxidation

Question 1

What is pyruvate oxidation?

Answer 1

brings and oxidates pyruvate into the mitochondra

pyruvate –> acetyl-CoA

Question 2

what are the steps of pyruvate oxidation?

enters outer membrane:
enters inner membrane (cristae):
1. decarboxylation:
2. dehydrogenation( redox reaction)
3. Coenzyme

Answer 2

enters outer membrane: diffusion
enters inner membrane (cristae): active transport

1. decarboxylation: CO2 is removed
2. redox reaction: NAD–> NADH Hydrogen is taken from pyruvate
3. Coenzyme: CoenzymeA is added product is made (acetyl-CoA)

Question 3

What is the ratio of pyruvate and NAD to acetyl-CoA an NADH and Hydrogen and CO2

pyruvate : NAD –> acetyle-CoA : NADH : H : CO2

Answer 3

pyruvate : NAD –> acetyle-CoA : NADH : H : CO2
2 : 2 : 2 : 2 : 2 : 2

Question 4

How does the pyruvate get through the outer vs inner membrane of the mitochondra?

Answer 4

Outer: passive transport
diffusion through pores

Inner: active transport
w/pyruvate translocase