Unit 3 Mass transport in Animals Flashcards
Describe what is meant by haemoglobin.
- Haemoglobins are groups of proteins found in different organisms
- Haemoglobin is a globular protein with a quaternary structure
- 4 haem groups with o2 bind to so can be transported around the body
Name 2 factors affecting oxygen-hemoglobin binding.
Partial pressure/concentration of oxygen/co2
Saturation of haemoglobin with oxygen
Define partial pressure and affinity
Partial pressure - a measure of the concentration of oxygen/carbon dioxide concentration in a cell
Affinity - Strength between 2 molecules
Describe the relationship between partial pressure of oxygen and haemoglobin saturation on the oxyhaemoglobin dissociation curve.
(HIGHER ON GRAPH)
More saturation = Loaded with oxygen
- Oxygen loads onto haemoglobin regions with a high partial pressure of oxygen e.g alveoli
(LOWER ON GRAPH))
Less saturation = Unloaded oxygen
- Oxyhaemoglobin unloads oxygen in regions with a low partial pressure of oxygen e.g respiring tissues
Describe cooperative binding and the shape on the oxyhaemoglobin dissociation curve.
(Same shape AS PREVIOUS)
- Cooperative nature due to
- Haemoglobin changing quaternary shape when first oxygen binds
- Shape change makes it easier for further oxygens to bind as another haem group available
Describe the Bohr effect and the effect on oxyhaemoglobin disassocation curves
- The Bohr effect is when a high carbon dioxide concentration causes oxyhaemoglobin curve to shift to right
- Causes haemoglobins affinity for oxygen to decrease by decreasing blood pH
- So haemoglobins shape changes slighly
Explain why oxygen binds to haemoglobin in lungs
- Partial pressure of oxygen is high
- Partial pressure of CO2 is low in lungs so affinity increases
Describe how hemoglobin is different in different organisms.
AND EXAMPLE
(SHIFTS TO LEFT ON GRAPH)
- Organisms living in low concentrations of oxygen have haemoglobin with a higher affinity for oxygen
(SHIFTS TO RIGHT ON GRAPH)
- Organisms that are very active have higher metabolism so more oxygen demand for respirtation and haemoglin with lower affinity for oxygen so more unloading
- Fetal haemoglobin has higher affinity for oxygen at same partial pressures so fetus haemoglobin can load oxygen off from mother haemoglobin
Describe the general pattern of blood circulation in a mammal.
Double circulatory system - Blood passes through the heart twice in each circuit
LUNGS
↑ ↓
↑ ↓
HEART
↑ ↓
↑ ↓
BODY
- In 1 circuit heart delivers blood to lungs
and in other circuit blood delivered to rest of body
Describe the blood vessels leaving the heart, kidney and lungs
LUNGS - Pulmonary artery - Pulmonary vein HEART - Vena cava - Aorta KIDNEYS - Renal vein - Renal artery
DEOXYGENTED BLOOD OXYGENATED BLOOD
Name all the parts of the heart including chambers, vessels and valves.
Relate the structure of the ATRIUM to their function.
2 ATRIUM
- Thin and elastic muscular walls so can stretch when filled with blood
Relate the structure of the VENTRICLES to their function.
2 VENTRICLES
RIGHT VENTRICLE = pumps blood to lungs
- Thick muscular walls but less thick than left ventricle so less pressure
- To prevent damage to capillaries in lungs
LEFT VENTRICLE = pumps blood to ROB
- Thicker muscular wall than right ventricle as higher pressure required so bigger contractions
- To ensure blood reaches all cells/respiring cells in body
Describe the veins and arteries which carry blood away and to the heart.
Vena cava = carries deoxygenated blood from body to heart
Pulmonary artery = carries deoxygenated blood from heart to lung
Pulmonary vein= carries oxygenated blood from lungs to heart
Aorta= carries oxygenated blood from heart to ROB
Describe the function of valves
- To prevent back flow of blood
- By only opening when pressure is higher behind the valve