Unit 3 Ch 12 Host Defenses 1 Flashcards
An infection in which the disease symptoms are influenced by more than one colonizer is termed an ___________ infection.
Polymicrobial
The total of all microbes found on and in a normal human is referred to as the human _________
Microbiome; biota
Organisms coming from somewhere in the same human host are considered _____________.
(Becoming established, Portals of Entry: To initiate an infection, a microbe entrees the tissue of the body by characteristic route, the portal of entry. Usually the skin or a mucous membrane.
Endogenous
Organisms coming from the outside of the body are exogenous.
Inflammation;
Disease;
Infection;
Pathology;
____________ can be characterized as any deviation from the healthy state.
Disease
A pathogen is a microbe whose relationship with its host is ____________ and results in infection and ________________.
Parasitic; disease
Exogenous microbes are likely to first encounter resistance from white blood cells that engulf and destroy pathogens by means of enzymes and antimicrobial chemicals.
These white blood cells are called: ___________
Phagocytes.
These cells ordinarily engulf and destroy pathogens by means of enzymes and antimicrobial chemicals
An infection in which the disease symptoms are influenced by more than one microbe is called a(n) ______________ infection.
POLYMICROBIAL; MIXED
The majority of infections are Polymicrobial, with contributions from more than one microbe, like the influenza cased by a virus and pneumonia (often caused by a bacterium). Influenza infection frequently leads to pneumonia.
- several types of skin infections are known to be caused by either Staphylococcus or Streptococcus species. When these 2 cultivated together with another common skin resident, MOraxella, both staph and strep increase their transcription of virulence factors. It is possible that the 3 of them together led to the disease symptoms.
Infection with a member of the normal biota, rather than an agent from the outside environment, is an example of an ______________ infection.
Endogenous infection
The 1st & 2nd lines of host defense are specific or nonspecific protections?
Nonspecific. Do not depend on specific acquisition.
Communication between separate fluid compartments of the body is conducted primarily through _____?
CAPILLARIES
A network of fibers & macrophages that permeates the tissues of the body is called the ____ ____ system.
MPS
Mononuclear Phagocyte System
Because it provides a passageway within & between tissues & organs, the ____ ____ system is intrinsic to the functions of the immune system.
MPS
Mononuclear phagocyte system
A compartmentalized network of vessels, cells, & protection against foreign materials is the ____ system.
Lymphatic
Major functions of the lymphatic system:
- Provides route for the extracellular fluid to return to the circulatory system proper
- drain off system for inflammmatory response
- render surveillance, recognition & protection against foreign materials through a system of lymphocytes, phagocytes & antibodies.
List the lymphoid organs
Spleen, Lymph nodes, Thymus
the flow of lymph goes what direction? Heart to extremities, or extremities to the heart?
from the extremities to the heart
Which cell types are produced in the red bone marrow?
Red blood cels, B-lymphocyte precursors, T-lymphocyte precursors
Although all blood cells originate in the bone marrow, only the ___ complete their maturation process here.
B-lymphocytes
Where T lymphocytes complete their maturation?
T lymphocytes migrate to the thymus to complete their maturation. Triangular structure two lobes in the lower neck region
List the major lymph nodes sites in the body.
3
- Armpit
- neck
- groin