Unit 3 Flashcards
Bartholin cysts are a unilateral painful lesion at which of the following sites?
Vestibule
Leukoplakia is present in all of the following except? A. Condyloma acuminate B. Lichen sclerosis C. Vulvar carcinoma D. Psoriasis
Condyloma acuminate
Parchment like skin is a feature of what?
Lichen sclerosis
Pre-eclampsia is characterized by endothelial dysfunction and is not associated with? A. Hematuria B. High blood pressure C. Edema D. Proteinuria
Hematuria
4yo girl presents with vaginal bleeding and grape-like mass on vagina. Biopsy shows malignant proliferation of immature skeletal muscle cells positive for desmin and myogenin. Dx?
Sarcoma botryoides
Which of the following types of HPV are responsible for 60% of cervical cancer cases?
HPV 16 and 18
What condition involves most of the epithelial cells of the cervix?
CIN-III
Cervical Intraepithelial Neoplasia - III
Or High Grade Squamous Intraepithelial Lesion (HSIL) w/ CIN-III (new classification)
Carcinoma not due to cigarette smoking? A. Mammary duct extasia B. Gastric neoplasia C. Pulmonary neoplasia D. Cervical intraepithelial neoplasia
Mammary duct ectasia
Gold standard for screening cervical carcinoma?
Pap smear
Asherman syndrome is due to?
Overaggressive D&C (dilation and curettage)
Which of the following cells is a classical histological feature of chronic endometritis?
Plasma cells
Common complication with chronic endrometritis?
Infertility
Which is not a risk factor from endometrial carcinoma? A. Endometrial polyp B. Obesity C. Late menopause D. Polycystic ovary syndrome
Endometrial polyp
Feature of type 2 serous carcinoma of endometrium?
Driven by p53 mutation
Common symptom of leiomyoma?
Abnormal uterine bleeding
Feature of leiomyosarcoma?
Bulky mass/single mass
Hormone that drives proliferative phase of endometrium?
Estrogen
Excess hormone primarily responsible for polycystic ovarian disease?
Lutenizing hormone
Polycystic ovarian disease is a risk factor for which of the following malignancies?
Endometrial carcinoma
35th week pregnant female with headaches, visual disturbances for 1 week, epileptic episode. Diagnosis?
Eclampsia
Most common group of ovarian tumors?
Surface epithelial tumors
Tissue present in struma ovarii?
Thyroid
Beta HCG persistently elevated in?
Hydatidiform mole
Most common source of Krukenburg Tumor?
Gastric carcinoma
Tumer marker employed to monitor treatment response in recurrence in pt’s with surface epithelial tumors of the ovary?
CA-125
Most common site of metastasis of cervical carcinoma?
Lungs
Hormone responsible for ejection of milk?
Oxytocin
Causes galactorrhea?
Hypothyroidism
Less common presentation of Paget Dz of the breast?
Nipple ulceration and erythema
Best treatment plan for mother with acute mastitis?
Antibiotics and continue breast feeding
35 year old woman with irregular mass in ULQ of breast, varies in size with menstrual cycle, no history of weight loss; what changes would you find in biopsy?
Fibrosis and cysts
Mammography should start annually at what age?
40
50 year old woman has bloody discharge from left nipple, small palpable masses in her breast; which is the most likely cause of discharge?
Intraductal papilloma
Non-neoplastic breast lesions associated with four to five fold increased risk of invasive cancer?
Atypical ductal hyperplasia
Genital lesion associated with a greater than expected risk of carcinoma of vulva?
Lichen sclerosis
Elevated androgen excretion, masculinization, hirsutism, are found in woman who has a tumor of ovary, tumor is made of polygonal cells and reinke crystals. Classification of tumor?
Sertoli-Leydig cell tumor
25 year old woman has work up for infertility, gyno found of foci of endometriosis, these foci are associated with?
Ovary
Comedo carcinoma of breast is a type of which of the following carcinomas?
Ductal carcinoma in situ
Biopsy specimen taken from unilateral erythematous eruption with scale crust, oozing nipple in a 50 year old woman. Dx?
Paget Dz of breast
42 year old female has pap smear, no remarkable finding on physical exam, current pap smear finding consistent with cervical intraepithelial neoplasia III, microscopic exam shows dysplastic cells that occupy full thickness of epithelium above the basement membrane. Most likely explanation for proceeding with cervical conization for this pt?
High risk of invasive carcinoma
Woman presents with parchment-like vulvar skin and thinning of epidermis. What does she have?
Lichen sclerosis
Not likely to cause cancer?
Endometrial polyps
Picture: has red and blue dots, involvement of broad ligament; what is it?
Endometriosis
MC place for endometriosis?
Ovaries
HCG elevated; what is it?
Choriocarcinoma
Picture: has grape-like masses; what lab needs to be evaluated?
Serum HCG
Picture of ovarian tumor that is mucinous; what is the marker for this?
No markers
Picture of ovarian tumor; what is associated with it?
(Answer has “Thyroid” in it)