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NMS-GU Path > Unit 3 > Flashcards

Unit 3 Flashcards

1
Q

Bartholin cysts are a unilateral painful lesion at which of the following sites?

A

Vestibule

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2
Q 
Leukoplakia is present in all of the following except?
A. Condyloma acuminate
B. Lichen sclerosis
C. Vulvar carcinoma
D. Psoriasis
A

Condyloma acuminate

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3
Q

Parchment like skin is a feature of what?

A

Lichen sclerosis

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4
Q 
Pre-eclampsia is characterized by endothelial dysfunction and is not associated with?
A. Hematuria
B. High blood pressure
C. Edema
D. Proteinuria
A

Hematuria

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5
Q

4yo girl presents with vaginal bleeding and grape-like mass on vagina. Biopsy shows malignant proliferation of immature skeletal muscle cells positive for desmin and myogenin. Dx?

A

Sarcoma botryoides

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6
Q

Which of the following types of HPV are responsible for 60% of cervical cancer cases?

A

HPV 16 and 18

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7
Q

What condition involves most of the epithelial cells of the cervix?

A

CIN-III

Cervical Intraepithelial Neoplasia - III

Or High Grade Squamous Intraepithelial Lesion (HSIL) w/ CIN-III (new classification)

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8
Q 
Carcinoma not due to cigarette smoking?
A. Mammary duct extasia
B. Gastric neoplasia
C. Pulmonary neoplasia
D. Cervical intraepithelial neoplasia
A

Mammary duct ectasia

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9
Q

Gold standard for screening cervical carcinoma?

A

Pap smear

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10
Q

Asherman syndrome is due to?

A

Overaggressive D&C (dilation and curettage)

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11
Q

Which of the following cells is a classical histological feature of chronic endometritis?

A

Plasma cells

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12
Q

Common complication with chronic endrometritis?

A

Infertility

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13
Q 
Which is not a risk factor from endometrial carcinoma?
A. Endometrial polyp
B. Obesity
C. Late menopause
D. Polycystic ovary syndrome
A

Endometrial polyp

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14
Q

Feature of type 2 serous carcinoma of endometrium?

A

Driven by p53 mutation

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15
Q

Common symptom of leiomyoma?

A

Abnormal uterine bleeding

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16
Q

Feature of leiomyosarcoma?

A

Bulky mass/single mass

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17
Q

Hormone that drives proliferative phase of endometrium?

A

Estrogen

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18
Q

Excess hormone primarily responsible for polycystic ovarian disease?

A

Lutenizing hormone

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19
Q

Polycystic ovarian disease is a risk factor for which of the following malignancies?

A

Endometrial carcinoma

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20
Q

35th week pregnant female with headaches, visual disturbances for 1 week, epileptic episode. Diagnosis?

A

Eclampsia

21
Q

Most common group of ovarian tumors?

A

Surface epithelial tumors

22
Q

Tissue present in struma ovarii?

A

Thyroid

23
Q

Beta HCG persistently elevated in?

A

Hydatidiform mole

24
Q

Most common source of Krukenburg Tumor?

A

Gastric carcinoma

25
Q

Tumer marker employed to monitor treatment response in recurrence in pt’s with surface epithelial tumors of the ovary?

A

CA-125

26
Q

Most common site of metastasis of cervical carcinoma?

A

Lungs

27
Q

Hormone responsible for ejection of milk?

A

Oxytocin

28
Q

Causes galactorrhea?

A

Hypothyroidism

29
Q

Less common presentation of Paget Dz of the breast?

A

Nipple ulceration and erythema

30
Q

Best treatment plan for mother with acute mastitis?

A

Antibiotics and continue breast feeding

31
Q

35 year old woman with irregular mass in ULQ of breast, varies in size with menstrual cycle, no history of weight loss; what changes would you find in biopsy?

A

Fibrosis and cysts

32
Q

Mammography should start annually at what age?

A

40

33
Q

50 year old woman has bloody discharge from left nipple, small palpable masses in her breast; which is the most likely cause of discharge?

A

Intraductal papilloma

34
Q

Non-neoplastic breast lesions associated with four to five fold increased risk of invasive cancer?

A

Atypical ductal hyperplasia

35
Q

Genital lesion associated with a greater than expected risk of carcinoma of vulva?

A

Lichen sclerosis

36
Q

Elevated androgen excretion, masculinization, hirsutism, are found in woman who has a tumor of ovary, tumor is made of polygonal cells and reinke crystals. Classification of tumor?

A

Sertoli-Leydig cell tumor

37
Q

25 year old woman has work up for infertility, gyno found of foci of endometriosis, these foci are associated with?

A

Ovary

38
Q

Comedo carcinoma of breast is a type of which of the following carcinomas?

A

Ductal carcinoma in situ

39
Q

Biopsy specimen taken from unilateral erythematous eruption with scale crust, oozing nipple in a 50 year old woman. Dx?

A

Paget Dz of breast

40
Q

42 year old female has pap smear, no remarkable finding on physical exam, current pap smear finding consistent with cervical intraepithelial neoplasia III, microscopic exam shows dysplastic cells that occupy full thickness of epithelium above the basement membrane. Most likely explanation for proceeding with cervical conization for this pt?

A

High risk of invasive carcinoma

41
Q

Woman presents with parchment-like vulvar skin and thinning of epidermis. What does she have?

A

Lichen sclerosis

42
Q

Not likely to cause cancer?

A

Endometrial polyps

43
Q

Picture: has red and blue dots, involvement of broad ligament; what is it?

A

Endometriosis

44
Q

MC place for endometriosis?

A

Ovaries

45
Q

HCG elevated; what is it?

A

Choriocarcinoma

46
Q

Picture: has grape-like masses; what lab needs to be evaluated?

A

Serum HCG

47
Q

Picture of ovarian tumor that is mucinous; what is the marker for this?

A

No markers

48
Q

Picture of ovarian tumor; what is associated with it?

A

(Answer has “Thyroid” in it)

NMS-GU Path (3 decks)

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