Unit 3 Flashcards
Role of Muscle Tissues (3)
- generate force
- generate movement (internally; move blood, waste, bones, etc.)
- generate heat (biochemical)
Properties of Muscle Tissue (5)
- Excitability
- Contractility
- Extensibility
- Elasticity
- Adaptability
Excitability
the ability to respond to stimulation (stimulus)
Contractility
the ability to shorten actively and exert a pull or tension that can be harnessed by connective tissues (response)
Extensibility
the ability to continue or contract over a range of resting lengths
Elasticity
the ability of a muscle to rebound toward its original length after a contraction
Adaptability
muscles will change in response to patterns in use (hypertrophy and atrophy - use it or lose it)
Muscle Types (3)
- striated skeletal
- cardiac
- smooth (internal organs)
Skeletal Muscle
- has striated appearance (indicate tight compact of myofilaments)
- multiple nuclei
- has fibers (=cells) 10-100um in diameter and lengths 100mm-1m
- myofilaments must be aligned in the muscles for contraction
Muscle Organization (smallest to largest)
muscle fiber > muscle fascicle > skeletal muscle
myo-
“muscle”
Myofibrils (=microfilaments)
- contractile proteins
- regulatory proteins (mediate contraction)
- accessory proteins (maintain alignment)
Contractile Proteins
- myosin
- actin
Myosin
- composes “thick” filaments
- consists of 2 intertwined heavy chains
- has bulbous “head” at extremes (fitted with hinge for swiveling)
Actin
- composes “thin” filaments
- consists of polymerized globular proteins
- includes paired, twisted actin polymers
Sarcomeres
- have crossbridges
- give rise to striations
- connect between actin and myosin
In the crossbridges…
- the A band does not change in distance
- when ATP binds, “actin slides over myosin”
- the I band and H zone shortens
Titin…
- provides elasticity and stabilizes myosin
- largest known protein
Nebulin…
- helps align actin
- makes sure actin slides in 1 plane
- makes sure actin is in correct position for myosin to bind (IMPORTANT)
- no nebulin can cause muscle paralysis
Muscle Contraction (simplified - 4 steps)
Chemical signal > electrical signals > Ca2+ signals > Excitation > Contraction/relaxation cycle
The Power Stroke
- Myosin heads bind actin filaments (bind to single monomer - specific)
- crossbridges push filaments inward
- myosin heads release actin filaments
- myosin heads bind NEW actin molecules
- must have control over power stroke
Tropomyosin
- is an elongated protein
- blocks myosin-binding sites (partially)
- allows weak actin-myosin binding
(resting position is blocking interaction)
Troponin
- controls position of tropomyosin
- binds calcium reversibly
2 Regulatory Proteins for Protein Contraction
- Tropomyosin
- Troponin
Contraction Regulation
- Increase cytosolic calcium
- Binds
- Tropomyosin shifts, exposing binding site on G-actin
- Power Stroke
- G-actin moves
Sarcomeres contain…
thick and thin filaments
Myofibrils are surrounded by…
sarcoplasmic reticulum that stores calcium
Muscle fibers are surrounded by…
endomysium
Muscle fascicles are surrounded by…
perimysium
Skeletal muscle is surrounded by…
epimysium
Properties of muscles and of the muscular system
- muscles have directionality (must pull in same plane and must be aligned; stretching)
-muscles work in antagonistic pairs for every plane of movement
Muscles must work in groups
- must engage large groups simultaneously
- use many muscles to actually function
Types of Skeletal Muscle Fibers (2)
- Fast (White) Fibers
- Slow (Red) Fibers
Fast (White) Fibers
- are larger in diameter - due to many densely packed myofibrils
- have low glycogen, low mitochondria
- fatigue easily
- can contract in 0.01 sec or less following stimulation
- minimal lag time - reflexes = white fibers
Slow (Red) Fibers
- 1/2 diameter of fast fibers
- more glycogen, more mitochondria, more myoglobin
- fatigue slowly
- contract 0.03-0.05 sec after stimulation (slower)
Force ____ as cross-sectional area ____.
increases, increases
Fascicle Orientations
- parallel
- bipennate
- multipennate
- circular
- convergent
Parallel
- give most range of motion
- least amount of force
- limited repetition
Bipennate
pennate - at an angle
- increases force
- less range of motion
Muscles - Supportive Structures
- tendons
- fascia
Tendons
- attach muscles to bones
- high tensile strength in same plane of contraction (soft tissue)
- lots of collagen
- composite nature gives it strength
Tendonitis
- inflammation of the tendon
- caused by:
overuse
impact
more common while growing
Fascia
- attach muscles to other muscles
- dermis to muscle connection
- not meant to endure strain
- is a network to hold things (muscles) in place
Dr. K’s 5 Golden Rules of Skeletal Muscle Movement
- All skeletal muscles cross at least one joint
- The bulk of skeletal muscles lies proximal to the joint crossed
- All skeletal muscles have at least 2 attachment points (origin and insertion)
- Skeletal muscles PULL; they cannot/do not push
- During contraction, the point of insertion moves toward the point of origin
EXCEPTIONS: lips and hands
Muscle Activity and Body Movement
- movement results when a muscle moves an attached bone
- 2 attachment points: origin and insertion
Origin
attachment to immoveable bone
Insertion
attachment to moveable bone
Types of Muscle Contraction
- Concentric
- Static or Isometric
- Eccentric
Concentric Contraction
- length of muscle shortens
- muscle force is greater than the resistance
“the weight will move because the muscle can generate more force than the weight”
Static or Isometric Contraction
- no change in muscle length
- muscle force is equal to the resistance
“the weight will not move”
Eccentric Contraction
- muscle lengthens
- muscle force is less than resistance
“putting the weight down or the weight has more force than the muscle can generate”
Role of Muscle
- agonist (bicep pulling up/tricep pulling down)
- antagonist (tricep relaxes/bicep relaxes)
(see Dr. K’s chart in notes)
Agonist
- prime mover
- provides the major force to complete the movement
Antagonist
- action opposes the agonist
Major Muscle Regions (7)
- arms
- shoulders
- back
- chest
- abdominals
- legs
- calves
Arm Muscles (2)
- biceps brachii
- triceps brachii
Biceps Brachii
- 2 heads
- parallel fibers
- prime mover for flexion of the forearm
- acts to supinate the forearm
- the antagonist for triceps brachii
Triceps Brachii
- parallel fibers
- prime mover of elbow extension
- antagonist of biceps brachii
Shoulders (Deltoids)
- triangular
- multipennate muscles that form the rounded shape of the shoulders
- the prime movers of abduction
Trapezius
- the most superficial muscles of the posterior neck and upper trunk
- extend the head
- elevate, depress, adduct, and stabilize the scapula
Back Muscles
- Trapezius
- Latissimus Dorsi
Latissimus Dorsi
- paired large, flat muscles
- with convergent fascicle arrangement that cover the lower back and flank
- assists in depression of the arm
- adducts, extends, and internally rotates the shoulder
- attaches to thoracic, lumbar, and illium
Pectoralis Major (Chest)
- large fan shaped convergent muscles
- cover the upper part of the chest and anterior wall of the axilla
- adduct and flexes the arm
- 3 regions that work together
(lift arm from your side)
Abdominals
- Rectus Abdominus
- External Obliques
Rectus Abdominus
- the most superficial muscles of the abdomen
- responsible for trunk flexion, forced expiration
- can work different parts with different exercises
External Obliques
- muscles with parallel fascicle orientation that forms the superficial lateral abdominal wall
- flex the trunk, assist expiration by depressing the ribs
- supports intra-abdominal viscera
- attaches to pubis
- can be part of groin and back pain
Legs
Anterior Surface
- sartorius
- quadriceps
- gracilis
Posterior Surface
- hamstring
Sartorius
- largest muscle we have
- from illiac crest to tibia
- extends the hip and extends/laterally rotates the knee
- inserts on tibia