Unit 2 Test--Neoplasms and Pain Flashcards
-oma suffix means what?
benign tumor
-carcinoma and -sarcoma suffixes means what?
malignant tumor
Characteristic of benign tumor?
Similar to normal cells, differentiated and mitosis fairly normal, relatively slow, localized expanding mass and frequently encapsulated.
Characteristic of malignant tumor?
Varied in size and shape with large nuclei, many undifferentiated cells, mitosis increased and atypical, rapid growth, cells not adhesive and invades nearby tissues or metastasizes to distant sites, may secrete enzymes or hormones, angiogenesis
What are the warning signs of cancer?
- Unusual bleeding or discharge anywhere in body
- Change in bowel or bladder habits.
- Change in wart or mole.
- Sore that does not heal.
- Unexplained weight loss
- Anemia, persistent fatigue
- A solid lump, often painless anywhere in body.
Local effects of tumors?
Pain
Obstruction
Tissue necrosis and ulceration
Systemic effects of tumors
Weight loss and cachexia Anemia severe fatigue effusions infections bleeding
What is the most dependable confirmation of malignancy?
Cytological tests (biopsy)
Invasion is
local spread, grows into adjacent tissues
Metastasis is
distant spread-further from origin
Staging of cancer
TNM; used to estimate prognosis
T-size of primary (t)umor
N-involvement of regional lymph (n)odes
M-spread of tumor (m)etastasis
Risk factors of cancer
genetic viruses radiation chemicals biological factors
Most common cancer in men
Prostate
lung
colorectal
Most common cancer in women
breast
lung
colorectal
Examples of malignant tumors
Skin
ovarian
brain
Causes of pain
Inflammation infection ischemia/tissue necrosis stretching of tissue chemicals burns muscle spasm
Somatic pain
From skin, bone muscle-conducted by sensory fibers
Visceral pain
originates in organs, conducted by sympathetic fibers and can be acute or chronic
Pain threshold
level of stimulation required to elicit a pain response, does not vary among individuals
Pain tolerance
ability to cope with pain, culturally related, varies among individuals
Afferent fibers
myelinated A delta, transmits impulses very rapidly–acute pain, sudden, sharp, localized.
Unmyelinated C fibers
transmits slowly, chronic pain, diffuse, dull, burning, itching or aching sensation.
Gate control theory
can modify pain stimuli conduction and transmission in the spinal cord and brain.
Gates open mean?
Pain impulses transmitted from the periphery to brain