Unit 2, Module 1 Glossary Flashcards
Polypeptide
A polymer consisting of a chain of amino acid residues joined by peptide bonds.
Gene
A length of DNA that codes for one (or more) polypeptides.
Genome
The entire DNA sequence of that organism. The human genome consists of about 3 billion nucleotide base pairs.
Protein
A large polypeptide - usually 100 or more amino acids. Some proteins consist of one polypeptide chain and some consists of more that one polypeptide chain.
Transcription
The creation of a single-stranded mRNA copy of the DNA coding strand.
Translation
The assembly of polypeptides at ribosomes.
Codons
Triplets of nucleotide bases.
Anticodon
Triplet of unpaired nucleotide bases on tRNA. Each anticodon can bind temporarily with its complementary codon.
Mutation
A change in the amount of, or arrangement of, the genetic material of a cell.
Chromosome mutations
Involve changes to parts of or whole chromosomes.
DNA mutations
Changes to genes due to changes in the nucleotide base sequences.
Point mutation
A DNA mutation in which one base pair replaces another. Also known as substitutions.
Substitutions
A DNA mutation in which one base pair replaces another. These are also called point mutations.
Insertion/deletion mutations
DNA mutation in which one or more nucleotide pairs are inserted or deleted from a length of DNA.
Allele
An alternative version of a gene. It is still at the same locus on the chromosome and codes for the same polypeptide but the alteration to the DNA base sequence may alter the protein’s structure.