Unit 2: Homeostasis (Lectures 1-2) Flashcards

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1
Q

What is homeostasis ?

A

The ability to maintain a steady state within a constantly changing environment

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2
Q

What are the 3 interdependent components of a homeostatic control mechanism ?

A

1) Receptor
2) Control centre
3) Effector

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3
Q

What is negative feedback ?

A

Anything that causes a change in direction opposite to that of the initial change. This returns it to its ‘ideal’ value

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4
Q

Are the majority of control mechanisms examples of positive or negative feedback ?

A

Negative

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5
Q

Give 3 examples of negative feedback mechanisms

A
  • Control of blood sugar
  • Regulation of temperature
  • Blood pressure
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6
Q

What is positive feedback ?

A

When a result is to enhance or exaggerate the original stimulus so activity (output) is accelerated

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7
Q

What do positive feedback mechanisms usually control ?

A

Episodic (infrequent) events that do not require continuous adjustments

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8
Q

Give 3 examples of positive feedback

A

1) Blood clotting
2) Labour contractions
3) Urination

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9
Q

What is autoimmunity ?

A

An overreactive immune response of the body against substances and tissues that are normally present in the body

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10
Q

How can autoimmunity lead to illness ?

A

As the immune system attacks self cells

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11
Q

What is the major role of electrolytes in the extracellular fluid ?

A

To ensure that fluid levels inside and outside the cell are balanced

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12
Q

How can a cell adjust its fluid levels ?

A

By changing the concentration of electrolytes

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13
Q

What is the concentration of Na+ in the extracellular fluid ?

A

142 mEq/L

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14
Q

What is the concentration of Na+ in the intracellular fluid ?

A

10 mEq/L

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15
Q

What is osmolarity ?

A

The concentration of a solution expressed as the total number of solute particles PER LITRE of solvent (mOsm/L)

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16
Q

What is osmolality ?

A

The concentration of a solution expressed as the total number of solute particles PER KG of solvent (mOsm/kg H2O)

17
Q

What is a measurement of plasma sodium below 142 called ?

A

Hyponatremia

18
Q

What is the cause of hyponatremia ?

A

Excess water- over hydration
Loss of sodium- Dehydration

19
Q

What is it called when the measurement of plasma sodium is above 142 ?

A

Hypernatremia

20
Q

What is hypernatremia ?

A

Excess sodium- over hydration
Loss of water- dehydration

21
Q

What is bicarbonate buffering ?

A

The regulation of CO2 by the lungs and HCO3- by the kidneys

22
Q

What is compensation ?

A

The restoration of PH despite disturbed [HCO3-] or pCO2

23
Q

What is correction ?

A

The restoration of normal PH , [HCO3-] and pCO2