Unit 2 Ch 35 liver, pancreatic, and gallbladder disorders Flashcards

1
Q

Cirrhosis, chronic liver disease

A

Progressive irreversible replacement of healthy liver tissue with scar tissue

Often irreversible unless early treatment 

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2
Q

Cause of chronic liver disease and cirrhosis

A

Chronic alcohol use most common
Chronic HBV or HCV
Fatty liver NASH
Dietary fat
Diabetes
Obesity
Heart disease 

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3
Q

Cirrhosis and chronic liver disease pathophysiology

A

Inflammation of liver cells
Infiltration with fat and white blood cells
Fibroid scar tissue, replaces liver tissue
Abnormal regeneration
Impaired liver, blood flow perfusion
Impaired liver functioning, bilirubin increases

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4
Q

Oliguria

A

No urine or a decreasing urine

Needs to be at least 30 mL an hour

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5
Q

Signs and symptoms of chronic liver disease

A

Asites build up
Lumpy, hard margins when pate liver
Clay colored stools
Liver produces clotting factors, risk of bleeding
Jaundice
Itching
Diarrhea or constipation

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6
Q

Amenorrhea

A

An abnormal absence of menstruating

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7
Q

Complications of cirrhosis, chronic liver disease

A

Clotting defects
Portal, hypertension
Varices
Ascites
Hepatic encephalopathy
Hepatorenal syndrome
Wernicke- Korsakoff syndrome

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8
Q

Wernicke- Korsakoff

A

Alcoholics, decrease thymine, and vitamin B

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9
Q

Diagnosing cirrhosis

A

Liver enzymes
Bilirubin
Ammonia
PT
Bleeding clotting
Abnormal x-ray or ultrasound
Duodenoscopy
Liver biopsy
Reduce sodium

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10
Q

Paracentesis

A

Take fluid out of stomach

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11
Q

Therapeutic intervention for cirrhosis

A

Ascites
diuretics
Sodium restriction
Albumin infusion
Paracentesis
Transjugular, intrahepatic, shunt
Vasoconstrictor
Vasile ligation
Transfusion
Antibiotic prophylaxis

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12
Q

Cirrhosis of the liver therapeutic interventions, hepatic encephalopathy

A

Lactulose
Rifaximin. Caravan
Neomycin. Neo-Fradin

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13
Q

Patient education for acute liver, failure, and cirrhosis

A

Disease process
Signs and symptoms to report
Adequate rest
Avoid narcotics, sedatives, tranquilizers and alcohol
Follow up here

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14
Q

Hepatitis

A

Inflammation of the cells of the liver

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15
Q

Causes of hepatitis

A

Bacterial infection
Medication’s
Alcohol
Chemicals toxic to the liver
Metabolic and vascular disorders
Often caused by a virus

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16
Q

Types of hepatitis found in the US

A

Hepatitis, a b and c

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17
Q

Hepatitis E

A

Travel contamination from human feces

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18
Q

Hepatitis d

A

If you have hepatitis d you usually have hepatitis B?

19
Q

How do you get hepatitis A?

A

Fecal oral route or from raw shellfish

20
Q

How do you get hepatitis B C and D

A

Healthcare related from body fluids

21
Q

Hepatitis prevention

A

Transmission precautions
Standard precautions
Hand hygiene
Vaccines
Immunoglobulin
Public health majors

22
Q

What is immunoglobulin?

A

It’s a passive short term protection doesn’t build up protection

23
Q

Hepatitis signs and symptoms

A

Can be asymptomatic
Prodromal stage
Flu like symptoms right upper quadrant pain
Icteric stage
Jaundice worsening symptoms
Convalescent
Returning to normal liver function

24
Q

What is convalescent?

A

Returning to normal

25
Q

Complications of hepatitis

A

Liver failure
Fulminant
Acute
Chronic
Chronic infection
Carrier of the virus
Puts you at risk of liver cancer

26
Q

What does fulminate mean?

A

Sudden and severe

27
Q

HBV and HCV

A

Chronic infection

28
Q

Hepatitis diagnostic test

A

Serum test
Liver enzymes
Serum bilirubin
Prothrombin
Serological test
Liver biopsy

29
Q

Hepatitis therapeutic interventions

A

Identify cause
Monitor liver function
Relieve symptoms
Prevent cirrhosis
Educate on hydration and nutrients
Rest
Avoid alcohol and liver, toxic drugs

30
Q

HBV and HDV therapeutic interventions

A

Pegylated interferon therapy

31
Q

HBV

A

Antivirals
Pegg related interferon therapy
Liver transplant

32
Q

Can you cure hepatitis B or hepatitis C?

A

No

33
Q

Types of antivirals that will treat hepatitis C

A

Albacore/grazoprevir
Sofosbivor/ledipasvir

34
Q

Gallbladder disorder

A

Inflammation of the gallbladder called cholecystitis

35
Q

Causes of gallbladder disorder

A

Risk increases with age
Family history
Bile stasis
High cholesterol
Fasting
Sedentary lifestyle
More often in women

36
Q

Signs and symptoms of gallbladder disorder

A

Silent stones
Elevated vital signs
Vomiting
Jaundice
Epigastric pain
Nausea
Indigestion
Right upper quadrant tenderness
Positive Murphy sign
Biliary colic

37
Q

What is a positive Murphy sign?

A

You can’t take a deep breath when your liver is pressed

38
Q

What is biliary colic?

A

Pain in your right shoulder and back. You should reduce fat intake.

39
Q

Complications of gallbladder disorder

A

Cholangitis
Necrosis perforation of the gallbladder
Empyema
Fistulas
Adenocarcinoma
Acute pancreatitis

40
Q

Cholangitis

A

Bile duct inflamed

41
Q

Empyema

A

Puss in plural cavity

42
Q

Diagnostic test for gallbladder disorder

A

Endoscopic ultrasound
CT scan
MRI
ERCP
HITA scan
White blood cells elevated
Elevated direct bilirubin

43
Q

Therapeutic interventions for gallbladder disorder

A

Analgesics
Bile acid sequestriants
Antiemetics
NPO

Low-fat diet

44
Q

Cholelithiasis treatment

A

Cholecystectomy
Laparoscopic surgery most common

Traditional surgery, T tube

Medication to dissolve stones