Unit 2 Flashcards
Micro tubule
Polymer of tubulin dimers. Key components of cilia and flagella. Helps cells withstand compression and maintain their shape. For the spindle apparatus which is important for cell division.
Micro filaments/Actin filament
Actin monomers. Reinforce the plasma membrane and organize proteins. Maintain the shape of the cell.
Intermediate filament
Provide cells with mechanical strength. Proteins that make up the intermediate filaments differ from one cell to another. Cable like structure and very resilient to stretch.
Tight junctions
Connects two cells in order to remove space between them
Gap junctions
Connections between cells that allows varies molecules and ions to directly pass through. Ex: sodium
DNA replication
Occurs in the nucleus and produces identical copies
DNA polymerase
Enzymes that create DNA molecules by assembling nucleotides
Double helix
Shape of DNA formed with anti parallel strands. Looks like a staircase
Antisense strand/Template strand
Serves as the source for the protein code
Sense (coding) strand
Compliment to the antisense strand and is the same as the new RNA strand synthesized from the antisense strand
5 prime end
Same for both DNA and RNA, contains the phosphate group
3 prime end
DNA containers hydrogen whereas RNA has a hydroxyl group
Leading strand
From 5’ to 3’ and is continuous replication
Lagging strand
From 5’ to 3’ and is replicated in fragments known as Okazaki fragments
Primer
Serves as a starting point for DNA synthesis because DNA polymerase requires an existing strand of nucleotides
Mutation
Occurs in DNA and is a permanent change in the nucleotide sequence
Silent mutations
Nucleotide substitution. Results in a different codon but the same amino acid forming from that codon.
Missense mutation
Different codon forms a different amino acid resulting in the replacement of an amino acid
Nonsense mutation
Creates a stop codon that terminates translation
Ex: UAG codon
Frameshift (insertion or deletion) mutation
Insertion or deletion of a nucleotide which results in a change of all the codons
Ex: cystic fibrosis where 3 nucleotides are deleted which results in a missing amino acid causing ion imbalances
Karyotype
Number and appearance of chromosomes in the nucleus
Chromosomes
Made up of DNA and proteins. Passed from parents to offspring. Includes your genetic makeup.
Gene
Region of DNA that encodes RNA or protein product and is responsible for phenotypic traits
Allele
Variant form of a gene. Humans are diploid because one allele is inherited from each parent.
Genotype
An individual’s collection of genes, or the inherited alleles