Unit 2 Flashcards
wrote a book about uroscopy
hippocrates
uroscopy means?
visual examination of urine
dark yellow to brownish color of urine (disease)
jaundice
red and foamy appearance (disease)
kidney disease
blood in the patient’s urine (disease)
urinary tract tumors
attract ants (disease)
diabetes
color charts had been developed that described the significance of 20 different colors of urine
1140 ce
discovered that a patient who has problems with kidney can have an increased protein which can be determined by boiling
frederik dekker
what disease is a kidney problem with increased protein
albuminuria
developed methods for quantitating microscopic sediment
thomas addis
microscopic sediment
addis count
year of the development of color charts
1950’s
introduced urinalysis as part of the doctor’s routine patient examination
richard bright
urine is comprised of approximately ________ water
95%
characteristics of urine (1)
ultrafiltrate of plasma
characteristic of urine (2)
readily available
characteristic of urine (3)
easy to collect but must be collected properly, including timed or random specimens
characteristic of urine (4)
inexpensively tested
characteristic of urine (5)
can give significant information about the patient’s disease
the testing of urine
urinalysis
clsi
clinical laboratory and standard institute
practice of examining urine for diagnostic purposes
urinalysis
it aids in following the course or treatment of disease
urinalysis
why perform urinalysis
for drug screening and aids in the diagnosis of the disease
the urinary tract system consists of two bean-shaped kidneys, the ______ and ________.
ureters and urethra
two bean-shaped organs located under diaphragm
kidneys
weight of kidney
150g
measurement of kidney
5cm x 12 cm
function of kidney
remove wastes and excess water from the blood to form urine
outer layer of kidney
cortex
inner layer of kidney
medulla
functional unit of kidney
nephron
each kidney contains __________ nephrons
1-1.5 million/kidney
made up of coils of capillaries
glomerulus
a long and narrow urine collecting tube
renal tubules
length of renal tubules
30-40 mm
two types of nephron
cortical and juxtamedullary
are situated primarily in the cortex of kidney
cortical
function is to concentrate urine
juxtamedullary
cortical nephrons are made up of _____ nephrons
85%
surround the proximal and distal convoluted tubules
peritubular capillaries
located adjacent to the ascending and descending loops of Henle in juxtamedullary nephrons only
vasa recta
- the area where the collecting tubules join together and empty freshly formed urine into the renal pelvis.
calyx
cavity area
renal pelvis
hormone which stimulates the bone marrow to produce red blood cells
erythropoietin
splits angiotensin 1 to angiotensin 2
renin
active form of vitamin D
calcitriol
produced by the adrenal cortex
aldosterone
muscular tube that connects the pelvis of the kidney to the bladder
ureter
where urine is stored until excretion
bladder
leads from the bladder allowing urine to be excreted
urethra
muscles called _____ enable the urethra to open and release the urine into the environment
sphincter muscle
the human kidneys receive approximately _____ of the blood pumped through the heart through the renal artery
5 liters
renal blood flow
1200 ml/min
renal plasma flow
600-700 ml/min
factors influencing filtration process (1)
hydrostatic pressure
factors influencing filtration process (2)
oncotic pressure
factors influencing filtration process (3)
renin-angiotensin-aldosterone system
factors influencing filtration process (4)
cellular structure of the capillary walls and Bowman’s capsule
RAAS
renin-angiotensin-aldosterone system
form intertwinning foot processes forming filtration slits
podocytes
prohibits the filtration of large molecules
shield of negativity
removes substances from the tubules for retention by the body
tubular reabsorption
major site for reabsorption
proximal convoluted tubule
occurs when substances to be reabsorbed combined with a carrier protein
active transport
movement of molecules across a membrane
passive transport
renal treshold of glucose
160/180 mg/dl
removes unneeded foreign waste substances that are not filtered by the glomerulus
tubular secretion
helps regulate acid-base and electrolyte balance
tubular secretion