Unit 11 Animal Physiology Flashcards
Smallpox
first infectious disease to be eradicated by vaccination
cowpox very similar
How do pregnancy tests work
monoclonal antibodies
https://www.youtube.com/watch?v=aOfWTscU8YM&feature=youtu.be
Cells are covered in uniquely shaped molecules
eg. polysaccharides of a bacterium’s cell wall, glycoproteins embedded in plasma membrane of eukaryote.
Surface molecules have wide range of functions (eg. include host binding for pathogens)
An organism recognises surface molecules present on its own cells, unsimilar surface molecules are regarded as foreign and provoke a specific immune response (antibody production)
Species Barriers regarding diseases (zoonosis)
Some pathogens are species specific (Polio, measles and syphilis only affect humans)
flu, ebola, salmonella, ets can be transmitted between species
A zoonosis is any disease of infection that is naturally transmissible from vertebrate animals to humans
Production of antibodies by Lymphocytes
Large variety of different lymphocytes and memory cells are present in blood.
Presence of antigen in blood is detected by one type of lymphocyte.
This lymphocyte will divide rapidly and produce a large number of cIone cells.
Each of activated lymphocyte clones then makes and secretes a specific antibody type.
This antibody binds to antigens detected in blood. Help phagocytosis of pathogens which have antigen on its surface.
B Cells
B-cell finds an antigen which matches its receptors.
waits to be activated by t-helper cell.
B-cell divides to produce plasma and memory cells.
plasma cells produce antibodies.
“eater cell” eats cells marked by plasmacells.
if the intruder invades again, memory cells help activate immune system.
Neutralisation
Attachment stops toxins from affecting or entering cells, viruses from invading cells, and bacteria from efficiently functioning and therefore attacking cells
Histamine
Released in white blood cells
Small organic molecule produced by two types of leukocyte: basophils and mast cells.
Loss of fluid from capillaries into surrounding tissues causes response symptoms: Inflammation/hives Itching Sneezing Watery eyes
Allergies are a group of conditions caused by hypersensitivity of immune system to something in environment that causes little or no problem on most people.
Antihistamine is a drug that opposes activity of histamine receptors
Mast cells are found in connective tissues. If simulated by an infection, they release histamine in infected area
Histamine has a number of effects upon body.
Key effect in immune response - increases permeability of capillaries to white blood cells and some proteins (eg. Antibodies). Allows components of immune system to engage pathogen early at site of infection.
Vaccines
Vaccination allow an individual to become immune to a disease without experiencing it.
Vaccines contain antigens in various forms that should not cause symptoms in a healthy person.
Monoclonal Antibody Production
An animal is injected with an antigen and in response produces specific plasma cells
Antagonistic muscle pairs in insect legs
plasma cells fused with tumor cells forming hydridoma
The elbow structure (biceps, triceps, humerus, radius/ulna, cartilage, synovial fluid, joint capsule, tendons, ligaments)
Biceps - Bends the arm (flexor)
Triceps - Straightens arm (extensor)
Humerus - anchors the muscle (muscle origin)
Radius/Ulna - Acts as forearm levers (muscle insertion) - radius for biceps, ulna for triceps
Cartilage - smooth surface to allow easy movement, absorbs shock and distributes load.
Synovial Fluid - provides lubrication, reduces friction in Joint.
Joint Capsule - Seals joint, contains synovial fluid.
Tendons - Non-elastic tissue connecting muscle to bone
Ligaments - Non-elastic tissue connecting bone to bone.
Sarcomere diagram
Dark bands - actin and myoin are overlapping
Light bands - shows actin fibres with no overlap
https://www.researchgate.net/figure/Striated-muscle-sarcomere-a-Schematic-diagram-showing-the-main-components-of-the_fig11_38012975
Types of Synovial Joints
Pivotal (vertebrae) Ball and socket (hip joint) Hinge joint (elbow) Condyloid joint (between radius and carpal bones or wrist) Plane joint (between tarsal bones) Saddle joint (between carpal bone and metacarpal bone)
Antagonistic Muscle Pairs
https://www.youtube.com/watch?v=_H4csvgZJ4s&feature=youtu.be
Muscles can only pull, not push
Therefore, work in pairs
One muscle of the pair contracts while the other relaxes.
as the agonist contracts, the antagonist relaxes or lengthens
Eg. Elbow - biceps/triceps
Knee - hamstrings/quadriceps
Striated Muscle Cells
Skeletal muscle tissue is striated
Dark and light bands
Contracts longitudinally
Muscle fibre cells are held together by plasma membrane (sarcolemma)
Multinucleated, with nuclei positioned along edges
Many mitochondria due to high demand of ATP
Contain sarcoplasmic reticulum (specialised ER) - stores calcium ions/pumps them out into sarcoplasm when muscle fibre is stimulated
Myofibril and Sarcomere
http://www.sumanasinc.com/webcontent/animati
ons/content/muscle.html
Basic rod like contractile units, grouped together inside muscle cells, which are known as muscle fibres
Sarcomere - repeating unit of striated muscle cell
In between z-lines - overlapping actin and myosin fibres.
Actin and myosin filaments
https://www.youtube.com/watch?v=U2TSaz8-yNQ&feature=youtu.be