Unit 10 - Alzheimers

Question 1

Plaques

Answer 1

Cluster of protein that builds up in between cells’neurons. Fragments mostly composed of Meta-Amyloid protein

Question 2

Tangles

Answer 2

Neurons getting tangled. Leads to cell death.

Question 3

Familial Alzheimer’s Disease

Answer 3

Almost always early onset, and genetics plays a great role. Genes PS1, PS2 and APP. less than 5%

Question 4

Sporadic Alzheimer’s Disease

Answer 4

Genetic susceptibility with the gene APOE4

Question 5

Sundowning

Answer 5

Increased behavioral problems for those with AD in the evening and during the night.

Question 6

Causes that contribute to sundowning

Answer 6

exhaustion, upset internal clock, increased shadows, caregiver exhaustion, disorientation

Question 7

Early AD symptoms

Answer 7

forgetfullness, difficulty learning new things, concentration, getting lost, mood shifts, communication issues, mild coordination problems, apathy

Question 8

Middle Stage AD

Answer 8

declining concentration, confusion, disorientation to time and space, language, decision making, mood shifts, restlessness, repetitive behavior, assistance required in daily life, changes in sleep and wake cycles

Question 9

Late Stage AD

Answer 9

Sever cognitive impairment, loss of recognizable speech, needing assistance with eating and cleaning, loss of ability to walk, impaired swallowing

Question 10

Brain changes with AD

Answer 10

shrunken cerebral cortex, hippocampus and plaques and tangles built up between neurons

Question 11

Modifiable risk factors

Answer 11

smoking, cholesterol, depression, exercise