Unit 1 - Hormonal Regulation of Blood Sugars Flashcards
Pancreas
Located behind the stomach, connected to the small intestine by the pancreatic duct.
–>Parts of the pancreas secretes enzymes into the small intestine (exocrine gland), but some parts secrete hormones directly into the bloodstream (endocrine gland).
Islets of Langerhans
Clusters of cells that produce hormones.
—>Contains two types of cells: Beta Cells and Alpha Cells.
Beta Cells
Produce insulin, decreases blood sugar level.
Alpha Cells
Produce glucagon, increased blood sugar level.
Insulin
Low blood sugar causes cells to take glucose into themselves, removing glucose from bloodstream.
–>Causes liver cells to take glucose, store ad glycogen.
–>Insulin caused body cells to take in glucose, used in cellular respiration.
Glucagon
High blood sugar causes liver cells to break glycogen into glucose, release into blood stream.
–> After a meal, high blood sugar triggers release of insulin.
–>During fasting, low blood sugar triggers release of glucagon.
Glucagon Level
Hyperglycemia: low insulin, high glucagon.
–>Diabetes Mellitus:
Type 1: Body unable to produce insulin, treated with insulin injection.
Type 2: Body doesn’t respond to insulin, treated with lifestyle changes (diet, exercise), medication.
SYMPTOMS: fatigue (glucose can’t move into cells because lack of insulin), large volumes of glucose-rich urine, thirst).
Hypoglycemia: high insulin, low glucagon.
–>Anxiety, shaking (hypoglycemia triggers stress response.
Antagonistic Hormones
Hormones that have opposite effects from one another.
—> PTH and Calcitonin
—> Glucagon and Insulin