unit 1: biochemistry - proteins, nucleic acid Flashcards

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1
Q

monomer unit of protein

A

amino acid

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2
Q

what bond forms when 2 amino acids join together?

A

peptide bond

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3
Q

4 structures of protein

A
  1. primary
  2. secondary
  3. tertiary
  4. quaternary
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4
Q

what is a primary structure? type of bond?

A
  • linear chain of amino acids (polypeptide)
  • peptide bonds
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5
Q

what is a secondary structure? type of bond?

A
  • spiraling or bending peptide bond
  • hydrogen bond
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6
Q

what is a tertiary structure? type of bond?

A

-alpha helix & pleated sheets twist & fold into 3-D shapes
- ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions

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7
Q

what is a quaternary structure? type of bond?

A
  • two or more polypeptides are fitted together in specific 3-D shape to form large protein
  • ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions
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8
Q

functions of protein

A
  1. enzymes
  2. structural proteins
  3. contractile proteins
  4. hormons
  5. transport proteins
  6. toxins
  7. storage proteins
  8. immunological proteins
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9
Q

enzymes

A

amylase - digests starch into proteins
- globular

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10
Q

structural protein

A

keratin (hair/nails), collagen (skin), fibrin (blood)
- fibrous

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11
Q

contractile proteins

A

actin/myosin - strained molecules
- fibrous

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12
Q

hormons

A

insulin/glucagon - regulates blood sugars
- globular

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13
Q

transport proteins

A

hemoglobin - carries oxygen & carbon dioxide in blood
- globular

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14
Q

toxins

A

neurotoxins - blocks nerve function
- globular

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15
Q

storage proteins

A

ferritin - stores iron in the spleen
- globular

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16
Q

immunological proteins

A

globulins - form complexes with foreign proteins
- globular

17
Q

2 shapes of protein

A
  1. globular
  2. fibrous
18
Q

globular

A
  • functional proteins
  • round
  • irregular amino acid chain
  • more sensitive
  • soluble
19
Q

fibrous

A
  • structural proteins
  • long/narrow
  • repetitive amino acid chain
  • less sensitive
  • insoluble
20
Q

what is denaturing?

A

process modifying molecular structure of protein

21
Q

how is denaturing beneficial?

A

when cooking meat, makes them easier to digest

22
Q

how is denaturing harmful?

A

when straightening hair, leads to loss of protein function

23
Q

essential amino acids

A

8, obtained through diet

24
Q

non-essential amino acids

A

12, manufactured by body

25
Q

monomer unit of nucleic acid

A

nucleotides

26
Q

groups nucleotides consists of..

A
  1. phosphate group
  2. pentose sugar
  3. nitrogenous base
27
Q

molecules nucleic acids make up..

A

DNA & RNA

28
Q

DNA

A
  • deoxyribose sugar
  • double stranded helix
  • forms genetic make up
  • contains thymine
29
Q

RNA

A
  • ribose sugar
  • single stranded alpha helix
  • turns genetic info. into protein
  • contains uracil
30
Q

nitrogenous bases

A

purines & pyrimidines

31
Q

purines

A
  • double ringed
  • adenine & guanine
32
Q

pyrimidines

A
  • single ringed
  • thymine, cytosine, uracil
33
Q

functions of nucleic acids

A
  • informational macromolecules
  • determining structural & functional characteristics
  • store & transfer genetic information
  • DNA & RNA
34
Q

antiparallel

A

parallel but running in opposite direction

35
Q

5’ location

A

located at free phosphate

36
Q

3’ location

A

located at free hydroxyl

37
Q

bonding in DNA

A
  • glycosyl bond
  • hydrogen bonds
  • phosphodiester bond
38
Q

nitrogenous base pairs

A

adenine — thymine , uracil
guanine — cytosine