unit 1: biochemistry - proteins, nucleic acid Flashcards

1
Q

monomer unit of protein

A

amino acid

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2
Q

what bond forms when 2 amino acids join together?

A

peptide bond

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3
Q

4 structures of protein

A
  1. primary
  2. secondary
  3. tertiary
  4. quaternary
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4
Q

what is a primary structure? type of bond?

A
  • linear chain of amino acids (polypeptide)
  • peptide bonds
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5
Q

what is a secondary structure? type of bond?

A
  • spiraling or bending peptide bond
  • hydrogen bond
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6
Q

what is a tertiary structure? type of bond?

A

-alpha helix & pleated sheets twist & fold into 3-D shapes
- ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions

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7
Q

what is a quaternary structure? type of bond?

A
  • two or more polypeptides are fitted together in specific 3-D shape to form large protein
  • ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions
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8
Q

functions of protein

A
  1. enzymes
  2. structural proteins
  3. contractile proteins
  4. hormons
  5. transport proteins
  6. toxins
  7. storage proteins
  8. immunological proteins
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9
Q

enzymes

A

amylase - digests starch into proteins
- globular

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10
Q

structural protein

A

keratin (hair/nails), collagen (skin), fibrin (blood)
- fibrous

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11
Q

contractile proteins

A

actin/myosin - strained molecules
- fibrous

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12
Q

hormons

A

insulin/glucagon - regulates blood sugars
- globular

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13
Q

transport proteins

A

hemoglobin - carries oxygen & carbon dioxide in blood
- globular

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14
Q

toxins

A

neurotoxins - blocks nerve function
- globular

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15
Q

storage proteins

A

ferritin - stores iron in the spleen
- globular

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16
Q

immunological proteins

A

globulins - form complexes with foreign proteins
- globular

17
Q

2 shapes of protein

A
  1. globular
  2. fibrous
18
Q

globular

A
  • functional proteins
  • round
  • irregular amino acid chain
  • more sensitive
  • soluble
19
Q

fibrous

A
  • structural proteins
  • long/narrow
  • repetitive amino acid chain
  • less sensitive
  • insoluble
20
Q

what is denaturing?

A

process modifying molecular structure of protein

21
Q

how is denaturing beneficial?

A

when cooking meat, makes them easier to digest

22
Q

how is denaturing harmful?

A

when straightening hair, leads to loss of protein function

23
Q

essential amino acids

A

8, obtained through diet

24
Q

non-essential amino acids

A

12, manufactured by body

25
monomer unit of nucleic acid
nucleotides
26
groups nucleotides consists of..
1. phosphate group 2. pentose sugar 3. nitrogenous base
27
molecules nucleic acids make up..
DNA & RNA
28
DNA
- deoxyribose sugar - double stranded helix - forms genetic make up - contains thymine
29
RNA
- ribose sugar - single stranded alpha helix - turns genetic info. into protein - contains uracil
30
nitrogenous bases
purines & pyrimidines
31
purines
- double ringed - adenine & guanine
32
pyrimidines
- single ringed - thymine, cytosine, uracil
33
functions of nucleic acids
- informational macromolecules - determining structural & functional characteristics - store & transfer genetic information - DNA & RNA
34
antiparallel
parallel but running in opposite direction
35
5' location
located at free phosphate
36
3' location
located at free hydroxyl
37
bonding in DNA
- glycosyl bond - hydrogen bonds - phosphodiester bond
38
nitrogenous base pairs
adenine --- thymine , uracil guanine --- cytosine