unit 1: biochemistry - proteins, nucleic acid Flashcards
monomer unit of protein
amino acid
what bond forms when 2 amino acids join together?
peptide bond
4 structures of protein
- primary
- secondary
- tertiary
- quaternary
what is a primary structure? type of bond?
- linear chain of amino acids (polypeptide)
- peptide bonds
what is a secondary structure? type of bond?
- spiraling or bending peptide bond
- hydrogen bond
what is a tertiary structure? type of bond?
-alpha helix & pleated sheets twist & fold into 3-D shapes
- ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions
what is a quaternary structure? type of bond?
- two or more polypeptides are fitted together in specific 3-D shape to form large protein
- ionic bond/hydrogen bond/disulfide bridges/hydrophobic interactions
functions of protein
- enzymes
- structural proteins
- contractile proteins
- hormons
- transport proteins
- toxins
- storage proteins
- immunological proteins
enzymes
amylase - digests starch into proteins
- globular
structural protein
keratin (hair/nails), collagen (skin), fibrin (blood)
- fibrous
contractile proteins
actin/myosin - strained molecules
- fibrous
hormons
insulin/glucagon - regulates blood sugars
- globular
transport proteins
hemoglobin - carries oxygen & carbon dioxide in blood
- globular
toxins
neurotoxins - blocks nerve function
- globular
storage proteins
ferritin - stores iron in the spleen
- globular
immunological proteins
globulins - form complexes with foreign proteins
- globular
2 shapes of protein
- globular
- fibrous
globular
- functional proteins
- round
- irregular amino acid chain
- more sensitive
- soluble
fibrous
- structural proteins
- long/narrow
- repetitive amino acid chain
- less sensitive
- insoluble
what is denaturing?
process modifying molecular structure of protein
how is denaturing beneficial?
when cooking meat, makes them easier to digest
how is denaturing harmful?
when straightening hair, leads to loss of protein function
essential amino acids
8, obtained through diet
non-essential amino acids
12, manufactured by body