Unit 1 Flashcards
What is DNA?
- Deoxyribonucleic acid
- two polypeptides in a helix shape
- antiparallel backbone, 3’ hydroxide end and 5’ phosphate end
- directs synthesis of mRNA
- provides directions for self-replication
What is RNA?
- ribonucleic acid
- one polypeptide, shape is not helical, complementary bonding can happen with itself or with another RNA
- mRNA interacts w/ protein-synthesizing systems to make a polypeptide
What are the base pairing rules?
In DNA
- Adenine and thymine
- Cytosine and guanine
In RNA
- Adenine and uracil
- Cytosine and guanine
- bonded though hydrogen bonds
What are the four levels of protein structure?
- Primary
- Secondary
- Tertiary
- Quaternary
Primary protein structure
- sequence of amino acids that form the polypeptide chain
- determined by inherited genetic information
Secondary protein strucure
-coils and folds in the polypeptide chain
- resulted from hydrogen bonds in the peptide backbone
- forms an alpha helix or a beta pleated sheet
Tertiary protein structure
- formed by interactions between multiple side chains
- interactions between R groups, hydrogen bonds, ionic bonds. hydrophobic interactions
- brings together helix and sheet
Quaternary protein structure
- when there are multiple polypeptide chains
What is a proteins function determined by
Structure and function are directly connected
What is a protein’s structure determined by
the polypeptide chain aka the sequence of amino acids
What happens when a protein is moved to a different temperature or pH?
- the structure may change and it will start to unravel
- denaturation –> loss of protein’s native structure
- change in function
- may do something different, nothing, or will just not do its job as well
What are the 6 major elements of life?
Carbon, hydrogen, oxygen, nitrogen, sulfur, phosphorus
How do you identify a carbohydrate?
- carbon, hydrogen, oxygen
How do you identify a lipid?
- long carbon skeleton
- carbon, hydrogen, oxygen sometimes phosphate
- hydrophobic (fatty acid tail) and hydrophilic (phosphate/glycerol head) section
How do you identify a polypeptide?
- repeating structure
- carboxyl end and amino end (c-terminus and n-terminus)
- has R groups
- amino acid chain
- sulfur is mainly in this macromolecule
How do you identify a nucleic acid?
- made of nucleotides
- sugar and phosphate backbone with nucleotides in the middle