Ulcerative colitis Flashcards
what areas of the GI tract can be affected by ulcerative colitis(UC)
confined to the colon and rectum
starts in rectum and works proximally
describe the onset of UC
over weeks
describe the lesions seen in UC
continuous(no skipping)
describe what affect NSAIDs and smoking have on UC
NSAIDs = make it worse smoking = protective
describe the presentation of UC
diarrhoea with blood + mucus, lower abdominal pain, faecal urgency, rectal bleeding on exam
describe the affect of UC on crypts
cryptitis, crypt abscesses, branching + irregular crypts and plasma cells are common at base of crypts
describe the ulceration seen in UC
superficial ulceration(submucosa and mucosa only) (pseudopolyps)
what are some complications of UC
toxic megacolon, colorectal cancer, blood loss
what complication of UC requires emergency surgical treatment
toxic megacolon