Ugat Ng Lahat

Question 1

May lead to irreversible blindness d/t ophthalmic artery occlusion
Associated with poly myalgia rheumatica
Commonly affects branches of carotid artery

Answer 1

Giant cell arteritis

Question 2

“Pulseless disease” -weak upper extremity pulses,fever,night sweats,arthritis,myalgia,skin nodules,ocular disturbances

Answer 2

Takayasu arteritis

-granulomatous thickening and narrowing of aortic arch and proximal great vessels

Question 3

Heavy smokers, ma les < 40 years old.
Intermittent claudication. May lead to
gangrene

Segmental thrombosing vasculitis with vein and
nerve involvement.
Treat with smoking cessation

Raynaud phenomenon is often present.

Answer 3

Buerger disease
(thromboangiitis
obliterans)

Question 4

Innumerable renal microaneurysms and spasms

on arteriogram.

Answer 4

Polyarteritis nodosa

Question 5

Conjunctiva! injection, Rash (polymorphous
- desquamating), Adenopathy (cervical),
Strawberry tongue (ora l mucositis) l!J, Ila nd-
foot changes (edema, erythema}, fever.

Answer 5

Kawasaki disease
(mucocutaneous
lymph node
syndrome)

Question 6

Immune complex vasculitis.

A5sociated with HLA-B51

Answer 6

Betchet syndrome

Question 7

Typically involves renal and visceral vessels, not
pulmonary arteries.
Transmural inflammation of the arterial wall
with fibrinoid necrosis.

Answer 7

Polyarteritis nodosa

Question 8

Recurrent aphthous ulcers, genital ulcerations,
uveitis,erythema nodosum.

Can be
precipitated by HSV or parvovirus

Answer 8

Betchet Syndrome

Question 9

Occurs 7-10 days after certa in medications
(penicillin, cepha losporins, phenytoin,
allopurinol) or infections (eg, HCV, HV).

Answer 9

Cutaneous small-

vessel vasculitis

Question 10

Asthma, sinusitis, skin nodules or purpura,

periphera l neuropathy (eg, wrist/foot drop).

Answer 10

Eosinophilic
granulomatosis with
polyangiitis (Churg-
Strauss)

Question 11

Granulomatous, necrotizing vasculitis with

eosinophilia .MPO-ANCA/p-ANCA, inc. lgE level

Answer 11

Eosinophilic
granulomatosis with
polyangiitis (Churg-
Strauss)

Question 12

Triad: 
• Focal necrotizing vasculitis 
• Necrotizing granulomas in lu ng a nd upper 
airway 
• Necrotizing glomerulonephritis

Answer 12

Granulomatosis
with polyangiitis
(Wegener)

Question 13

Classic triad: 
• Skin: palpable purpura on buttocks/legs D 
• Arthralgia 
• Cl: abdominal  pain (associated with 
intussusception)

Answer 13

lmmunoglobulin A
vasculitis

Also known as llenoch-Schiinlein purpura.
Most common childhood systemic vasculitis.
Often follows URL

Question 14

Vasculitis 2° to IgA immune complex
deposition.
Associated with lgA nephropathy (Buerger
disease)

Answer 14

lmmunoglobulin A

vasculitis

Question 15

Necrotizing vasculitis commonly involving
lung, kidneys, and skin with pauci-immune
glomerulonephritis and palpable purpura.

Answer 15

Microscopic
polyangiitis

MPO-ANCA/p-ANCA (anti-
myeloperoxidase).
Treat with cyclophosphamide, corticosteroids.

Question 16

Triad of palpable purpura, weakness, arthralgias.

May also have peripheral neuropathy and renal
disease (e.g. glomerulonephritis)

Answer 16

Mixed cryoglobulinemia

Notes :

Cryoglobulins are immunoglobulins that precipitate in the cold.
Vasculitis due to mixed lgC and IgA immune complex deposition.