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GG Sa Ecg > En-do-crime > Flashcards

En-do-crime Flashcards

1
Q

Hashimoto

A

Auto

Lympho

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2
Q

Markers for hashimoto

A

Tug antibody

Tpo

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3
Q

Invasive fibrous thyroiditis

Wood thyroid

A

Riedel thyroditis

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4
Q

Post viral thyrioditis

Painful

A

De quervain ,sub acute

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5
Q

Goiter
Hyperthyroidism
Exopthalmus

Excess circulating thyroid hormones
Tsk -r or tsab -diagnostic

A

Graves’ disease

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6
Q

Inhibit t4-t3 peripheral conversion

A

PTU

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7
Q

Inhibit TPO function
Reduce antibody level
Enhance rates of remission

A

Ptu, methimazole

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8
Q

SSKI

A

Thyroid storm

Before surgery

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9
Q

Plummer’s dse. (Toxic adenoma)

A

Hyperthyroidism from a single hyper functioning nodule

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10
Q

Myxedema (gull disease)

A 
Hypothyroidism in older or adult 
Slowing of physical and mental 
Cold intolerance 
Overweight 
Drop in symphathetic activity 
Constipation
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11
Q

Major cause -release of inflammatory cytokines
Low ft3,normal t4,and tsh
Low t4-poor prognosis
Routine acutely I’ll patients- no need

A

Sick euthyroid syndrome

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12
Q

Thyroid cancer risk factors associated with?

Head and neck irradiation

Iodine def.

Men 2

A

Papillary ca

Follicular ca

Medullary ca

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13
Q

Mc thyroid cancer

Psammoma bodies

A

Papillary thyroid cancer

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14
Q

Psammoma bodies

A

Papillary thyroid cancer

Meningioma

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15
Q

Cannot be diagnosed in FNAB along with hurtle cell carcinoma
IODINE DEFICIENCY

A

Follicular

Dx : vascular and capsular invasion

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16
Q 
Production of calcitonin 
Local invasion is more common 
Para follicular cells 
FamiLial -MEN 2 
Poor prognosis: older,male,higher mitotic act., small cell type
A

Medullary thyroid cancer

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17
Q

Lymphoma treatment

A

CHOP
- cyclophosphamide,vincristine, doxurubucin, prednisone
Regional radiation

18
Q

Poor prognostic fix for FTC

A 
Distant metastasis 
>50
>4cm
Hurtle cell 
Marked vascular invasion
19
Q

Complete or near total insulin deficiency

A

T1DM

20
Q

Insulin resistant

Impaired insulin secretion

A

T2DM

21
Q

Ketosis prone

A

T1DM
1a -autoimmune
1b - iodiopathic

22
Q

GdM screening

A

24-8 weeks ago

23
Q

Risk factors for Type 2

A

Fam hx
Obesity >25
Physical inactivity

Hx 
> kg/9 lbs 
Hba1c 5.7-6.4
Hpn 
PCOS -Stein leventhal syndrome 
Hx of heart disease 
Triglycerides >250
24
Q

Criteria for diagnosis of DM

A 
Symptoms PPP
\+
Rbs = >200mg/dl or 11.1 mmol\l
Fbs = > 126 mg/dl or 7 mmol/l
HbA1c - >6.5 %
2-hr plasma glucose >200 mg/dl OGTT
25
Q

Screening

A

Rbs

Fbs

OGTT

26
Q

Confirmatory

A

OGTT

27
Q

Monitoring

A

HbA1c

Fructosamine test \glycosylated albumin

28
Q

Reflects glycemic status over the prior 2 weeks

A

Fructosamine essay

29
Q

Hypoglycemia
Low plasma glucose
Relief of symptoms after giving glucose or sugars

A

Whipples triad

30
Q 
Inadequate insulin administration 
Pregnancy 
Infarction 
Drug-coccaine
Infection 
S/s 
Nausea,thirst 
Abdominal pain
Sob
Tachycardia 
Dehydration/phone
Kussmauls breathing 
Acetone breath
A

Keto acidosis

31
Q

MODY 123456

A 
1 - HNF4@
2- glucokinase gene
3 - HNF @1
4- IPF -1
5- HNF -1b
6 - neuroD1
32
Q

Due to mutations in hepetonuclear Transcription factors

A

MODY 123

33
Q

Thyroid hormone synthesis normally begins at about

A

about 11 weeks AOG

34
Q

Thyroid size

A

12–20 g in size, highly vascular, soft in consistency

35
Q

Thyroid glands develops during what AOG

A

3rd week

36
Q

Thyroid medullary C cells

A

produce calcitonin

37
Q

Wolff- chaikoff effects

A

Iodine induced hypothyroidism

38
Q

Jod basedow effects

A

Iodine induced hyperthyroidism

39
Q

Treatment for hypothyroidism

Goal of treatment ?

A

Levothyroxine

Normalization of tsh

40
Q

Treatment recommended: pregnant/wishes to conceive, TSH

A

> 10 mIU/L

41
Q

state of thyroid hormone excess and is not synonymous with hyperthyroidism which is the result of excessive thyroid function.

A

Thyrotoxicosis

42
Q

Drug induced thyroiditis

A

Amiodarone

GG Sa Ecg (5 decks)

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