UC vs Crohns

Question 1

effects of smoking?

Answer 1

aggravated crohn’s disease but protects against UC

Question 2

what three factors contribute to the pathogenesis?

Answer 2

1. genetic predisposition
2. mucosal immune system
3. environmental factor

Question 3

skip lesions from mouth to anus?

Answer 3

Crohn’s disease

Question 4

inflammation of all layers, goblet cells, granulomas

Answer 4

Crohn’s disease

Question 5

bloody diarrhoea?

Answer 5

ulcerative colitis

Question 6

abdominal pain?

Answer 6

Crohn’s disease

Question 7

continuous disease from ileocaecal valve to the rectum

Answer 7

ulcerative colitis

Question 8

colorectal cancer

Answer 8

ulcerative colitis

Question 9

predisposes you to primary sclerosing cholangitis

Answer 9

ulcerative colitis

Question 10

weight loss?

Answer 10

crohn’s disease

Question 11

non-bloody diarrhoea

Answer 11

crohn’s disease

Question 12

uveitis

Answer 12

ulcerative colitis

Question 13

no inflammation beyond the submucosa, crypt abscesses

Answer 13

ulcerative colitis

Question 14

bowel obstruction, fistulae

Answer 14

crohn’s disease

Question 15

what is common to both ulcerative colitis and crown’s disease?

Answer 15

diarrhoea
arthritis
erythema nodosum

Question 16

Cause of crohn’s?

Answer 16

cause is unknown but there is a strong genetic susceptibility

Question 17

when do UC/CD present?

Answer 17

UC - peaks from 15-25, and 55-65

CD - adolescence/early adulthood

Question 18

urgency, tenesmus, left lower quadrant pain

Answer 18

UC

Question 19

perianal disease - skin tags or ulcers

Answer 19

crohn’s disease