Mean age of onset?
Crohn's = 20s UC = 30s
More common in females or males?
Crohn's = Males UC = Females
Location?
Crohn's = Anywhere in the GI Tract UC = Limited to colon and rectum
Pattern of inflammation?
Crohn's = Skip lesions, patchy UC = Continious
Inflammation?
Crohn's = Transmural UC = Superficial
Granulomas present?
Crohn's = YES UC = NO
Fistulae occurance?
Crohn's = Common UC = Incredibly Rare
Cancer Risk?
Crohn's = Moderate UC = Higher
Chance of requiring surgery?
Crohn's = 50-80% UC = 20%
Complications?
Crohn's = Fistulae, Abscess, Stricture UC = Rare for there to be complications, Toxic Megacolon is one
Interaction with smoking?
Crohn's = Harmful UC = Protective
Classic Presentation
Crohn's = RIF Pain, Abdominal Bloating, Malabsorption UC = Bloody Diarrhoea, Bloating, Less severe than Crohn's
Treatment
Crohn's = Steroids, Immunosuppression, Surgery UC = 5-ASA, Steroids, Immunosuppression, Surgery
Describe surgery?
Crohn's = Partial Resection UC = Whole Colon