U4 AOS 1 (adaptive immunity) Flashcards
Third line of defence
Adaptive immune system composed of the humoral and cell-mediated responses.
**create a pathogen specific response.
Immunological Memory
The production of B and T memory cells that allows the immune system to combat a previously encountered pathogen quickly and aggressively.
Antigen presentation
a subgroup of phagocytes that display the antigens from consumed pathogens on their surface and interact with the adaptive immune system.
Humoral Immunity
an adaptive immune response in which extracellular pathogens are targeted by specific antibodies produced by plasma cells. Also known as B cell immunity.
Cell-mediated Immunity
an adaptive immune response in which infected or abnormal cells are destroyed by cytotoxic T cells. Also known as T cell immunity.
Antibody
a protein produced by plasma cells during the adaptive immune response that is specific to an antigen and combats pathogens in a variety of ways. Also known as immunoglobulin.
T Lymphocyte
a type of lymphocyte that plays an important role in cell-mediated immunity. It differentiates into cytotoxic T cells, T memory cells, and T helper cells.
T Helper Cell
a type of differentiated T lymphocyte that supports the functioning of a number of different immune cells, including the cloning and differentiation of selected T and B cells.
B Lymphocyte
a type of lymphocyte that plays an important role in humoral immunity and differentiates into plasma cells and B memory cells.
Clonal Expansion
the process in which many copies of a lymphocyte are generated
Clonal Selection
the process in which B and T cells encounter an antigen that matches their antigen- binding site, and then generate many copies of themselves.
Differentiation
the process in which cells develop specialised characteristics, typically transforming them from one cell type to another more specialised cell type.
Plasma Cell
a differentiated B lymphocyte that is responsible for the generation and secretion of antibodies during the humoral response
B Memory Cell
a differentiated B lymphocyte that is responsible for providing long-lasting immunological memory of an antigen.
Cytotoxic T Cell
a differentiated T lymphocyte that is responsible for the destruction of infected or abnormal cells.