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[3Y1S] MT 6320 > U2.2.1 Gr (+) Cocci : Streptococcus > Flashcards

U2.2.1 Gr (+) Cocci : Streptococcus Flashcards

1
Q

Streptococcus & Enterococcus

Family

A

Streptococcacee

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2
Q

Streptococcus & Enterococcus

Morphology

A

Gram (+) cocci in chains

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3
Q

Streptococcus & Enterococcus

Morphology of S. pneumoniae

A

diplococci

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4
Q

Streptococcus & Enterococcus

Select all that apply
Generalities of Streptococcus
1. Facultative Anaerobes
2. Non motile and Non-sporeformers
3. Catalase Positive
4. Some may require 5-10% CO2 for growth

A

1,2,4

Catalase Negative

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5
Q

Streptococcus & Enterococcus

Select all that apply
Generalities of Streptococcus
1. Resistant to Vancomycin
2. Require enriched or supportive media (BAP)
3. Many members are normal flora and not opportunistic
4. Causes a wide spectrum of infections

A

2, 4

Susceptible to Vancomycin, 3 - are opportunistic

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6
Q

3 types of classification of Streptococci and Enterococci

A
  1. Sherman’s (Physiologic)
  2. Rebecca Lancefield Classification
  3. Brown’s Classification
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7
Q

Sherman’s Classification

Grows at 37C; Pus forming

A

Pyogenic

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8
Q

Sherman’s Classification

Grows at 37C and 45C

A

Viridans

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9
Q

Sherman’s Classification

4 species classified as viridans

A

S. salivarius, S. mutans, S. mitis, S, sanguis

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10
Q

Sherman’s Classification

Grows at 10C and 37C

A

Lactic

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11
Q

Sherman’s Classification

Grows at 10C, 37C and 45C

A

Enterococcal

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12
Q

Classification of Streptococci & Enterococci

Basis: Grouped based on the cell wall polysaccharide (Common C Carbohydrate) Antigen and cell wall teichoic acids

A

Rebecca Lancefield Classfication

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13
Q

Rebecca Lancefield Classfication

Clinically significant that has cell wall polysaccharide

A

A, B, C, F and G

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14
Q

Rebecca Lancefield Classfication

Clinically significant that has cell wall techoic acids

A

D and Enterococcus

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15
Q

Classification of Streptococci & Enterococci

Basis: Hemolytic Patterns

A

Brown’s Classification

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16
Q

Brown’s Classification

Species that show Beta Hemolysis

A

Group A, B, C, F & G

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17
Q

Brown’s Classification

Species that show Alpha Hemolysis

A

S. pneumoniae

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18
Q

Brown’s Classification

Species that show Gamma Hemolysis

A

Group D Enterococcus

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19
Q

Brown’s Classification

Species that show alpha-prime hemolysis

A

Viridans

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20
Q

Group A Streptococcus

Group A Beta Hemolytic Streptococcus & colonizers skin & throat

A

Streptococcus pyogenes

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21
Q

Group A Streptococcus

Streptococcus pyogenes
- antigenic structure [2]

A

Gr (+) Cell Wall (Peptidoglycan) and Presence of M Protein

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22
Q

Grp A Streptococcal Infections

Most common manifestation includes tonsilitis and pharyngitis

A

Bacterial Pharyngitis

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23
Q

Grp A Streptococcal Infections

Strep Throat

A

Bacterial Pharyngitis

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24
Q

Grp A Streptococcal Infections

resembles
pharyngitis with Skni rash.” desquamation of skin;
“strawberry tongue”

A

Scarlet Fever

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25
Grp A Streptococcal Infections production of ____ toxin is present in scarlet fever
eryhtrogenic toxin
26
Grp A Streptococcal Infections T/F Group A Streptococcal infections also causes to impetigo cellulitis & erysipelas.
T
27
Grp A Streptococcal Infections "Flesh Eating Disease"
Necrotizing Fascitis
28
Grp A Streptococcal Infections "Suppurative Fasciitis", Hospital Gangrene, Necrotizing Erysipelas
Necrotizing Fascitis
29
Grp A Streptococcal Infections Necrosis of skin, subcutaneous fat and fascia
Necrotizing Fascitis
30
Grp A Streptococcal Infections caused by Pyogenic Exotoxin A
Streptococcal Toxic Shock Syndrome
31
Grp A Streptococcal Infections Includes Acute Rheumatic Fever and Rheumatic Heart Disease & Acute Glomerulonephritis
Poststreptococcal Sequelae
32
Grp A Streptococcal Infections Drug of Choice
Penicillin or Erythromycin
33
Pathogenic Determinants of Grp A Strep (Extracellular) causes fever; skin rash of scarlet fever; Blood brain alteration; organ damage
Erythrogenic/Pyogenic Toxins A,B,C
34
Pathogenic Determinants of Grp A Strep (Extracellular) protease implicated in flesh eating streptococci
Exotoxin B
35
Pathogenic Determinants of Grp A Strep (Extracellular) causes lysis of blood clots; spread of infection
Streptokinase
36
Pathogenic Determinants of Grp A Strep (Extracellular) caused by mucoid colonies (capsulated); antiphagocytic
M Protein
36
Group B Streptococcus Normal Flora of GI Tract, Pharynx and Vaginal Tract AR
Streptococcus agalactiae
37
Pathogenic Determinants of Grp A Strep (Extracellular) induce proliferation of host I-lymphocytes
Superantigens
38
Group B Streptococcus Grp B Beta Hemolytic Clinically important species
Streptococcus agalactiae
39
Pathogenic Determinants of Grp A Strep (Extracellular) mediates epithelial cell attachment
Protein F
40
Group B Streptococcus causes Mastitis in Cattle and Invasive Disease in Newborns
Streptococcus agalactiae
40
Group B Streptococcus Antigenic Structure of Streptococcus agalactiae
Group BSpecific Antigen (acid stable)
41
Group B Streptococcus Select All Neonatal Infections caused by Grp B Streptococcus 1. Pneumonia 2. Endocarditis 3. Meningitis 4. Bacteremia leading to Death
1, 3, 4
42
Group B Streptococcus T/F Grp B Streptococcus causes puerperal sepsis and maternal septicemia
T
43
Group B Streptococcus Select all that apply Adult Infections 1. Skin Infections 2. UTIs 3. Bacteremia 4. Septicemia 5. Endocarditis 6. Endometritis 7. Cardiomegaly
1, 2, 3, 5, 6
44
Group B Streptococcus Drug of Choice
Penicillin
45
Group B Streptococcus Select all Pathogenic Determinants 1. Streptolysin O 2. Hemolysin 3. Capsule 4. CAMP Factor
2, 3, 4
46
Group B Streptococcus Select all Pathogenic Determinants 1. DNASE 2. RNASE 3. Hyalurodinase 4. Protease
1, 3, 4
47
Streptococcus Ability to grow in 40% bile and Hydrolyze Esculin
Group D Streptococcus and Enterococcus
48
Group D Streptococcus Two subgroups
1. Enterococcus 2. Non-enterococcus
49
Group D Streptococcus Gr(+) Cocci that are normal flora of GI tract of animals and humans
Enterococcus
50
Group D Streptococcus All produce Group D Antigen
Enterococcus
51
Group D Streptococcus Able to Grow under extreme conditions
Enterococcus
52
Group D Streptococcus Clinically significant Species of Enterococcus
E. faecalis, E. faecium, E. durans and E. avium
53
Group D Streptococcus : Enterococcus T/F Enterococcus is susceptible to Penicillin G
F, resistant
54
Group D Streptococcus : Enterococcus Drug of Choice
Combination of cell wall inhibitor such as vancomycin or ampicillin and an aminoglycoside such as gentamicin or streptomycin
55
Group D Streptococcus : Enterococcus Select All Pathogenic Determinants 1. Hyalurodinase 2. able to grow in extreme conditions 3. Gelatinase 4. Cytolysin 5. Surface Adhesin protein
2, 3, 4, 5
56
Group D Streptococcus : Enterococcus Select all that apply Infections 1. UTI 2. Endocarditis 3. Septic Arthritis 4. Bacteremia
1, 2, 4
57
Group D Streptococcus : Enterococcus Select all that apply Infections 1. Wound infections 2. Intraabdominal abscesses 3. Pneumonia 4. Osteomyelitis
1, 2
57
Group D Streptococcus
58
Group D Streptococcus : Non Enterococci species
Streptococcus bovis group
58
Group D Streptococcus : Non-Enterococci High association with Colon Cancer
Streptococcus bovis group
58
Group D Streptococcus Agents of bacteremia, septicemia and endocarditis
Non-enterococci Streptococcus bovis group
59
Group C Streptococcus Select all that apply Infections 1. Endocarditis 2. Severe pharyngitis 3. Pneumonia 4. Cellulitis 5. Abscess
2, 3, 4, 5
59
Group D Streptococcus : Non Enterococci examples of Streptococcus bovis group
S. equinus, S. gallolyticus
60
Group C Streptococcus Examples of Group C
DEEZ S. equi Streptococcas equsimilis Streptococcus zooepidemicus Streptococcus dysagalactiae
60
Group C Streptococcus Species that causes strangles among horses
S. equi
61
Miscellaneous Lancefield Groups Group of Streptococcus anzinosus
Group F and G
62
Genus Streptococcus usually Normal Flora of oropharynx
Viridans Streptococci
62
Miscellaneous Lancefield Groups Causes bacteremia and liver abscess
Streptococcus anzinosus
62
Miscellaneous Lancefield Groups Culture used for Group F & G
Honeysuckle Odor
63
Genus Streptococcus do not possess Polysaccharide Component
Viridans Streptococci
64
Miscellaneous Lancefield Groups Normal flora of the GI tract, vaginal tract and oropharynx
Group G
65
Genus Streptococcus: Viridans Strep Select all Viridans Streptococci 1. S. mutans 2. S. intermedius 3. S. mitis 4. S. sanguis 5. S. constellatus 6. S. equi 7. S. salvarius
2, 3, 4, 5, 7
65
Viridans Streptococcus Select all Infections 1. Subacute Bacterial Endocarditis 2. Pneumonia 3. Dental Caries 4. Hepatomegaly 5. Abscess and bacteremia 6. Gingivitis
1, 3, 5, 6
66
Viridans Streptococcus Select all Pathogenic Determinants 1. Polysaccharide Capsule 2. Cytolysin 3. Hyalurodinase 4. Glucans 5. Dextrans
1, 2, 4, 5
67
Streptococcus Diplococcus or Pneumococcus
Streptococcus pneumonia
68
Streptococcus Gr(+) cocci in pairs
S. pneumoniae
69
Streptococcus May be a normal flora of the Upper Respiratory Tract of pre-school children
Streptococcus pneumonia
70
Streptococcus pneumoniae Select all 1. Bacterial Pneumonia (Lobar Pneumonia) 2. Septicemia 3. Meningitis 4. Otitis media 5. Bacteremia 6. Sinusitis
1, 3, 4, 5, 6
71
S. pneumoniae Select All Virulence Determinants 1. Polysaccharide Capsule 2. Pneumolysin 3. IgE protease 4. Hyalurodinase 5. IgA protease 6. DNAse 7. Neuraminidase
1, 2, 4, 5, 7
72
Streptococcus like organisms Nutritionally Variant Streptococci
Abiotrophia and Granulicatella
73
Streptococcus like organisms viridans streptococci that require cysteine or vitamin B6
Abiotrophia and Granulicatella
74
Streptococcus like organisms satelliting streptococci
A. defectiva
75
Streptococcus like organisms satelliting streptococci, thiol requiring or pyridoxal requiring streptococci
A. adjacens and A. defective, G. adiacens
76
Strep-like Organisms Common airborne organism
Aerococcus
77
Strep-like Organisms Causes endocarditis, wounds & abscesses
Gemella
78
Strep-like Organisms previously Group N and causes UTI & Endocarditis
Lactococcus
79
Strep-like Organisms an opportunistic pathogen found in plant surfaces, vegetables and milk products
Leuconostoc
79
Strep-like Organisms

[3Y1S] MT 6320 (8 decks)

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