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[3Y1S] MT 6320 > U2.2.1 Gr (+) Cocci : Streptococcus > Flashcards

U2.2.1 Gr (+) Cocci : Streptococcus Flashcards

1
Q

Streptococcus & Enterococcus

Family

A

Streptococcacee

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2
Q

Streptococcus & Enterococcus

Morphology

A

Gram (+) cocci in chains

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3
Q

Streptococcus & Enterococcus

Morphology of S. pneumoniae

A

diplococci

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4
Q

Streptococcus & Enterococcus

Select all that apply
Generalities of Streptococcus
1. Facultative Anaerobes
2. Non motile and Non-sporeformers
3. Catalase Positive
4. Some may require 5-10% CO2 for growth

A

1,2,4

Catalase Negative

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5
Q

Streptococcus & Enterococcus

Select all that apply
Generalities of Streptococcus
1. Resistant to Vancomycin
2. Require enriched or supportive media (BAP)
3. Many members are normal flora and not opportunistic
4. Causes a wide spectrum of infections

A

2, 4

Susceptible to Vancomycin, 3 - are opportunistic

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6
Q

3 types of classification of Streptococci and Enterococci

A
  1. Sherman’s (Physiologic)
  2. Rebecca Lancefield Classification
  3. Brown’s Classification
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7
Q

Sherman’s Classification

Grows at 37C; Pus forming

A

Pyogenic

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8
Q

Sherman’s Classification

Grows at 37C and 45C

A

Viridans

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9
Q

Sherman’s Classification

4 species classified as viridans

A

S. salivarius, S. mutans, S. mitis, S, sanguis

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10
Q

Sherman’s Classification

Grows at 10C and 37C

A

Lactic

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11
Q

Sherman’s Classification

Grows at 10C, 37C and 45C

A

Enterococcal

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12
Q

Classification of Streptococci & Enterococci

Basis: Grouped based on the cell wall polysaccharide (Common C Carbohydrate) Antigen and cell wall teichoic acids

A

Rebecca Lancefield Classfication

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13
Q

Rebecca Lancefield Classfication

Clinically significant that has cell wall polysaccharide

A

A, B, C, F and G

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14
Q

Rebecca Lancefield Classfication

Clinically significant that has cell wall techoic acids

A

D and Enterococcus

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15
Q

Classification of Streptococci & Enterococci

Basis: Hemolytic Patterns

A

Brown’s Classification

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16
Q

Brown’s Classification

Species that show Beta Hemolysis

A

Group A, B, C, F & G

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17
Q

Brown’s Classification

Species that show Alpha Hemolysis

A

S. pneumoniae

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18
Q

Brown’s Classification

Species that show Gamma Hemolysis

A

Group D Enterococcus

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19
Q

Brown’s Classification

Species that show alpha-prime hemolysis

A

Viridans

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20
Q

Group A Streptococcus

Group A Beta Hemolytic Streptococcus & colonizers skin & throat

A

Streptococcus pyogenes

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21
Q

Group A Streptococcus

Streptococcus pyogenes
- antigenic structure [2]

A

Gr (+) Cell Wall (Peptidoglycan) and Presence of M Protein

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22
Q

Grp A Streptococcal Infections

Most common manifestation includes tonsilitis and pharyngitis

A

Bacterial Pharyngitis

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23
Q

Grp A Streptococcal Infections

Strep Throat

A

Bacterial Pharyngitis

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24
Q

Grp A Streptococcal Infections

resembles
pharyngitis with Skni rash.” desquamation of skin;
“strawberry tongue”

A

Scarlet Fever

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25
Q

Grp A Streptococcal Infections

production of ____ toxin is present in scarlet fever

A

eryhtrogenic toxin

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26
Q

Grp A Streptococcal Infections

T/F Group A Streptococcal infections also causes to impetigo cellulitis & erysipelas.

A

T

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27
Q

Grp A Streptococcal Infections

“Flesh Eating Disease”

A

Necrotizing Fascitis

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28
Q

Grp A Streptococcal Infections

“Suppurative Fasciitis”, Hospital Gangrene, Necrotizing Erysipelas

A

Necrotizing Fascitis

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29
Q

Grp A Streptococcal Infections

Necrosis of skin, subcutaneous fat and
fascia

A

Necrotizing Fascitis

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30
Q

Grp A Streptococcal Infections

caused by Pyogenic Exotoxin A

A

Streptococcal Toxic Shock Syndrome

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31
Q

Grp A Streptococcal Infections

Includes Acute Rheumatic Fever and Rheumatic Heart Disease
& Acute Glomerulonephritis

A

Poststreptococcal Sequelae

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32
Q

Grp A Streptococcal Infections

Drug of Choice

A

Penicillin or Erythromycin

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33
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

causes fever; skin rash of scarlet fever; Blood brain alteration; organ damage

A

Erythrogenic/Pyogenic Toxins A,B,C

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34
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

protease implicated in flesh eating streptococci

A

Exotoxin B

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35
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

causes lysis of blood clots; spread of infection

A

Streptokinase

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36
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

caused by mucoid colonies (capsulated); antiphagocytic

A

M Protein

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36
Q

Group B Streptococcus

Normal Flora of GI Tract, Pharynx and Vaginal Tract
AR

A

Streptococcus agalactiae

37
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

induce proliferation of host I-lymphocytes

A

Superantigens

38
Q

Group B Streptococcus

Grp B Beta Hemolytic Clinically important species

A

Streptococcus agalactiae

39
Q

Pathogenic Determinants of Grp A Strep (Extracellular)

mediates epithelial cell attachment

40
Q

Group B Streptococcus

causes Mastitis in Cattle and Invasive Disease in Newborns

A

Streptococcus agalactiae

40
Q

Group B Streptococcus

Antigenic Structure of Streptococcus agalactiae

A

Group BSpecific Antigen (acid stable)

41
Q

Group B Streptococcus

Select All
Neonatal Infections caused by Grp B Streptococcus
1. Pneumonia
2. Endocarditis
3. Meningitis
4. Bacteremia leading to Death

42
Q

Group B Streptococcus

T/F Grp B Streptococcus causes puerperal sepsis and maternal septicemia

43
Q

Group B Streptococcus

Select all that apply
Adult Infections
1. Skin Infections
2. UTIs
3. Bacteremia
4. Septicemia
5. Endocarditis
6. Endometritis
7. Cardiomegaly

A

1, 2, 3, 5, 6

44
Q

Group B Streptococcus

Drug of Choice

A

Penicillin

45
Q

Group B Streptococcus

Select all
Pathogenic Determinants
1. Streptolysin O
2. Hemolysin
3. Capsule
4. CAMP Factor

46
Q

Group B Streptococcus

Select all
Pathogenic Determinants
1. DNASE
2. RNASE
3. Hyalurodinase
4. Protease

47
Q

Streptococcus

Ability to grow in 40% bile and Hydrolyze Esculin

A

Group D Streptococcus and Enterococcus

48
Q

Group D Streptococcus

Two subgroups

A
  1. Enterococcus
  2. Non-enterococcus
49
Q

Group D Streptococcus

Gr(+) Cocci that are normal flora of GI tract of animals and humans

A

Enterococcus

50
Q

Group D Streptococcus

All produce Group D Antigen

A

Enterococcus

51
Q

Group D Streptococcus

Able to Grow under extreme conditions

A

Enterococcus

52
Q

Group D Streptococcus

Clinically significant Species of Enterococcus

A

E. faecalis, E. faecium, E. durans and E. avium

53
Q

Group D Streptococcus : Enterococcus

T/F Enterococcus is susceptible to Penicillin G

A

F, resistant

54
Q

Group D Streptococcus : Enterococcus

Drug of Choice

A

Combination of cell wall inhibitor such as vancomycin or ampicillin and an aminoglycoside such
as gentamicin or streptomycin

55
Q

Group D Streptococcus : Enterococcus

Select All
Pathogenic Determinants
1. Hyalurodinase
2. able to grow in extreme conditions
3. Gelatinase
4. Cytolysin
5. Surface Adhesin protein

A

2, 3, 4, 5

56
Q

Group D Streptococcus : Enterococcus

Select all that apply
Infections
1. UTI
2. Endocarditis
3. Septic Arthritis
4. Bacteremia

57
Q

Group D Streptococcus : Enterococcus

Select all that apply
Infections
1. Wound infections
2. Intraabdominal abscesses
3. Pneumonia
4. Osteomyelitis

57
Q

Group D Streptococcus

58
Q

Group D Streptococcus : Non Enterococci species

A

Streptococcus bovis group

58
Q

Group D Streptococcus : Non-Enterococci

High association with Colon Cancer

A

Streptococcus bovis group

58
Q

Group D Streptococcus

Agents of bacteremia, septicemia and endocarditis

A

Non-enterococci Streptococcus bovis group

59
Q

Group C Streptococcus

Select all that apply
Infections
1. Endocarditis
2. Severe pharyngitis
3. Pneumonia
4. Cellulitis
5. Abscess

A

2, 3, 4, 5

59
Q

Group D Streptococcus : Non Enterococci

examples of Streptococcus bovis group

A

S. equinus, S. gallolyticus

60
Q

Group C Streptococcus

Examples of Group C

A

DEEZ
S. equi
Streptococcas equsimilis
Streptococcus zooepidemicus Streptococcus dysagalactiae

60
Q

Group C Streptococcus

Species that causes strangles among horses

61
Q

Miscellaneous Lancefield Groups

Group of Streptococcus anzinosus

A

Group F and G

62
Q

Genus Streptococcus

usually Normal Flora of oropharynx

A

Viridans Streptococci

62
Q

Miscellaneous Lancefield Groups

Causes bacteremia and liver abscess

A

Streptococcus anzinosus

62
Q

Miscellaneous Lancefield Groups

Culture used for Group F & G

A

Honeysuckle Odor

63
Q

Genus Streptococcus

do not possess Polysaccharide Component

A

Viridans Streptococci

64
Q

Miscellaneous Lancefield Groups

Normal flora of the GI tract, vaginal tract and oropharynx

65
Q

Genus Streptococcus: Viridans Strep

Select all
Viridans Streptococci
1. S. mutans
2. S. intermedius
3. S. mitis
4. S. sanguis
5. S. constellatus
6. S. equi
7. S. salvarius

A

2, 3, 4, 5, 7

65
Q

Viridans Streptococcus

Select all
Infections
1. Subacute Bacterial Endocarditis
2. Pneumonia
3. Dental Caries
4. Hepatomegaly
5. Abscess and bacteremia
6. Gingivitis

A

1, 3, 5, 6

66
Q

Viridans Streptococcus

Select all
Pathogenic Determinants
1. Polysaccharide Capsule
2. Cytolysin
3. Hyalurodinase
4. Glucans
5. Dextrans

A

1, 2, 4, 5

67
Q

Streptococcus

Diplococcus or Pneumococcus

A

Streptococcus pneumonia

68
Q

Streptococcus

Gr(+) cocci in pairs

A

S. pneumoniae

69
Q

Streptococcus

May be a normal flora of the Upper Respiratory Tract of pre-school children

A

Streptococcus pneumonia

70
Q

Streptococcus pneumoniae

Select all
1. Bacterial Pneumonia (Lobar Pneumonia)
2. Septicemia
3. Meningitis
4. Otitis media
5. Bacteremia
6. Sinusitis

A

1, 3, 4, 5, 6

71
Q

S. pneumoniae

Select All
Virulence Determinants
1. Polysaccharide Capsule
2. Pneumolysin
3. IgE protease
4. Hyalurodinase
5. IgA protease
6. DNAse
7. Neuraminidase

A

1, 2, 4, 5, 7

72
Q

Streptococcus like organisms

Nutritionally Variant Streptococci

A

Abiotrophia and Granulicatella

73
Q

Streptococcus like organisms

viridans streptococci that require cysteine or vitamin B6

A

Abiotrophia and Granulicatella

74
Q

Streptococcus like organisms

satelliting streptococci

A

A. defectiva

75
Q

Streptococcus like organisms

satelliting streptococci, thiol requiring or pyridoxal requiring streptococci

A

A. adjacens and A. defective,
G. adiacens

76
Q

Strep-like Organisms

Common airborne organism

A

Aerococcus

77
Q

Strep-like Organisms

Causes endocarditis, wounds & abscesses

78
Q

Strep-like Organisms

previously Group N and causes UTI & Endocarditis

A

Lactococcus

79
Q

Strep-like Organisms

an opportunistic pathogen found in plant surfaces, vegetables and milk products

A

Leuconostoc

79
Q

Strep-like Organisms

[3Y1S] MT 6320 (8 decks)

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