u2: endocrine system Flashcards
is the endocrine or nervous system faster?
- endocrine can take seconds to days
- nervous reacts to stimuli within 1 to 10 sec
- thus, endocrine is slower + longer acting effects
paracrine signalling
cell to cell communication where a cell releases a chemical messenger, causing changes in NEARBY cells
endocrine signalling
signals (hormones) produced in one part of the body travel through circulation to reach far-away targets
wht is the endocrine system comprised of?
all hormone-secreting cells and glands in the body
what are the types of hormones?
- lipid (steroid)
- water-soluble
define lipid (steroid) hormones
diffuse through lipid bilayer and bind to receptor proteins to activate specific genes
define water-soluble hormones
attach to receptor on plasma membrane which activates enzymes (or effector molecules) inside cell that trigger protein prod’n
examples of lipid (steroid) hormones
- estrogen
- progesterone
- testosterone
- aldosterone
examples of water-soluble hormones
- epinephrine
- norepinephrine
- Thyroid-stimulating hormone (TSH)
- human growth hormone (hGH)
how does the thyroid gland system work?
- thyroid gland releases thyroxine (T3 nd T4)
- anterior pituitary gland releases TSH which causes thyroid to release thyroxine.
- since thyroxine increases, it is noticed by hypothalamus and anterior pituitary gland and the prod’n of TSH is stopped
menstrual cycle
monthly cycle of events in a sexually mature female which prepares the uterus for implantation of a fertilized egg
endometrium
tissue lining the uterus
follicle
structure in ovary which contains an oocyte (immature egg/ovum)
corpus luteum
- temporary endocrine structure found in ovary which secretes progesterone and estrogen
- follicle after egg has been released
menstrual cycle: day 1-6
- drop in hormone lvls (estrogen/progesterone) indicate body isn’t pregnant
- triggers shedding of endometrium
menstrual cycle: day 7-14
- FSH lvls rise, follicle begins developing
- as follicle develops, estrogen lvls increase = increase in LH
- endometrium thickens + blood supply increases to prep for fertilization
menstrual cycle: day 14-15
follicle produces a mature egg which bursts from ovary (ovulation)
menstrual cycle: day 16-28
- egg travels down fallopian tube where it may be fertilized
- corpus lutem develops and secretes progesterone to thicken endometrium
- if fertilization doesn’t happen, cycles starts again at day 1
how does stress make u hungrier?
- cortisol and adrenaline hormones rise, causing removal of glycogen from liver to get energy
- once stress is gone, body replaces glycogen from liver
male reproductive system
- hypothalamus in brain releases GnRH
- GnRH signals pituitary gland to release LH and FSH: (LH increases prod’n of testosterone, which helps make sperm + FSH increases prod’n of molecules for spermatogenesis) = positive feedback loop
- if testosterone lvls too high, GnRH/FSH/LH restrcited = negative feedback loop