type 2 oral meds Flashcards

1
Q

sulfonylureas MOA

A

stimulates beta cells to secrete more insulin and decrease the liver’s production of glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

when does someone take sulfonylureas during the day?

A

BID: 30 min before first and last meal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

sulfonylureas interactions

A

NSAIDS
sulfas
coumadin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

glipizide (Glucotrol)

A

sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

biguanides MOA

A

inhibits production of glucose by the liver & increases sensitivity to insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

caution with IV contrast dye

A

metformin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

alpha-glucosidase inhibitors MOA

A

delays absorption of complex carbs & slows entry of glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

alpha-glucosidase inhibitors SE

A

hypoglycemia
GI
must be taken with first bite of food

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

nonsulfonylureas MOA

A

stimulates pancreas to secrete more insulin, short half life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

nonsulfonylureas SE

A

hypoglycemia
weight gain
interacts with antifungals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

repaglinide (Prandin)

A

nonsulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

thiazolidinediones MOA

A

makes body tissue more sensitive to insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

thiazolidinediones SE

A

hypoglycemia
weight gain
anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

sodium glucose co-transporter 2 inhibitors MOA

A

prevents kidneys from reabsorbing glucose back into the blood and then releasing into the urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

sodium glucose co-transporter 2 inhibitors SE

A

UTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
  • flozine
A

sodium glucose co-transporter 2 inhibitors

17
Q

dipeptidyl peptides MOA

A

increases and prolongs incretin

18
Q

dipeptidyl peptides SE

A

hypoglycemia
risk for pancreatitis
GI upset
sore throat

19
Q

GLP-1 MOA

A

enhances glucose dependent insulin secretion

20
Q

daily injection

A

glucagon like peptide 1 agonist
GLP-1

21
Q

GLP-1 SE

A

increased risk of thyroid cancer, pancreatitis, weight loss, GI upset, n/v//

22
Q

contraindicated with gastroparesis

A

GIP-1