type 2 oral meds Flashcards
sulfonylureas MOA
stimulates beta cells to secrete more insulin and decrease the liver’s production of glucose
when does someone take sulfonylureas during the day?
BID: 30 min before first and last meal
sulfonylureas interactions
NSAIDS
sulfas
coumadin
glipizide (Glucotrol)
sulfonylurea
biguanides MOA
inhibits production of glucose by the liver & increases sensitivity to insulin
caution with IV contrast dye
metformin
alpha-glucosidase inhibitors MOA
delays absorption of complex carbs & slows entry of glucose
alpha-glucosidase inhibitors SE
hypoglycemia
GI
must be taken with first bite of food
nonsulfonylureas MOA
stimulates pancreas to secrete more insulin, short half life
nonsulfonylureas SE
hypoglycemia
weight gain
interacts with antifungals
repaglinide (Prandin)
nonsulfonylurea
thiazolidinediones MOA
makes body tissue more sensitive to insulin
thiazolidinediones SE
hypoglycemia
weight gain
anemia
sodium glucose co-transporter 2 inhibitors MOA
prevents kidneys from reabsorbing glucose back into the blood and then releasing into the urine
sodium glucose co-transporter 2 inhibitors SE
UTI