Type 2, 3, and 4 Diseases & Their Antigens Flashcards

1
Q

AI hemolytic anemia

A

Rh blood group antigens

I antigen

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2
Q

AI thrombocytopenia purpura

A

Platelet integrin

GP2b:3a

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3
Q

Goodpasture’s

A

basement membrane (Type 4 collagen)

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4
Q

Pemphigus vulgaris

A

Epidermal cadherin

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5
Q

Pemphigus follaceus

A

Desmoglein

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6
Q

Acute Rheumatic Fever

A

Strep cell wall antigens (cross react with cardiac myocytes)

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7
Q

Graves

A

TSHr

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8
Q

Myasthenia Gravis

A

AchR

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9
Q

T2DM

A

Insulin receptor (antagonist)

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10
Q

Hypoglycemia

A

Insulin receptor (agonist)

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11
Q

Hypoglycemia

A

Insulin receptor (agonist)

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12
Q

Subacute bacterial endocarditis

A
bacterial antigen 
(type 3)
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13
Q

Mixed essential cryoglobulinemia

A

Rheumatoid factor IgG complexes (with or without HepC antigens)
(type3)

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14
Q

SLE

A

DNA, histones, ribosomes, snRNP, scRNP

type 3

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15
Q

T1DM

A

Pancreatic Beta-cell antigen

type 4

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16
Q

RA

A

Unknown synovial joint antigen

type 4

17
Q

Multiple Sclerosis

A

Myelin basic protein, proteolipid protein

type 4