Type 1- 1

Question 1

What type of hypersz is associated with intestinal worms?

Answer 1

TYPE 1

Question 2

What type hypersz exaggerates the T helper cells response?

Answer 2

Type 1

Question 3

Type 1 = excessive amount of Ig__ —> atopy

Answer 3

E

Question 4

Type 1 = genes and environmental factors = ________

Answer 4

Allergies

Question 5

After a vx, what 2 types increase?

Answer 5

1 and 3

Question 6

Type 1= IL-__ overproduction

Answer 6

4

Question 7

IL-4 overproduction = ________ Th2 activation and B cell stimulation

Answer 7

Increased

Question 8

FcER = ________ affinity and irreversible binding

Answer 8

Increases

Question 9

FCE__ = present in mast cells, basophils, neutrophils, eosinophils, macrophages, and DCs

Answer 9

I

Question 10

FCE ____ = present in B cells, NK cells, macrophages, DCs, eosinophils, and platelets

Answer 10

II

Question 11

Type 1:
1) Mast cell with IgE and antigen
2) Degranulation
3) Acute __________ and systemic effects

Answer 11

Inflammation

Question 12

Bio active molecules are released by mast cells and basophil when antigen cross-links 2 Ig__ molecules on mast cell surface

Answer 12

E

Question 13

IL- 4 produced by Th2 —> released —> promotes development of more Th2 = major sources of this cytokine promotes Ig __ responses

Answer 13

E

Question 14

What cells may serve as an initial source of IL-4?

Answer 14

NK cells

Question 15

What is inhibited by IFN-y and IL-12?

Answer 15

IL-4

Question 16

What cells express trimeric FcERI?

Answer 16

DCs

Question 17

Allergy Loop:
DCs express trimeric FcERI —> binds antigen Ig-E complexes = simulated Th__ response = secrete cytokines = promote IgE response

Answer 17

2

Question 18

What complement receptors is located in B, T, and DC cells?

Answer 18

2

Question 19

What cells have the following characteristics:
-CR2
-Located in intestine, skin, airways, around nerves,
-Close to blood vessels,
-Release pro-inflammatory mediators

Answer 19

Mast cells